Biomedical Informatics, Bioinformatics and Cyberinfrastructure Enhancement Core

生物医学信息学、生物信息学和网络基础设施增强核心

• 批准号: 10252030
• 负责人: Mary Helen Mays
• 金额: $ 19.37万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-02 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10252030
• 关键词: Acute; Bioinformatics; Cardiometabolic Disease; Caribbean region; Caring; Clinical; Clinical Data; Clinical Research; Clinical Trials; Communicable Diseases; Communities; Conduct Clinical Trials; Continuing Education; Data; Data Collection; Development; Disasters; Disease; Education; Effectiveness; Electronic Health Record; Emerging Communicable Diseases; Environment; Face; Goals; Health; Health Insurance Portability and Accountability Act; Health Personnel; Health Status; Healthcare; Hispanics; Hospitals; Individual; Informatics; Infrastructure; Institution; Knowledge; Language; Lead; Malignant Neoplasms; Maps; Medical; Medicine; Online Systems; Outcome; Participant; Pathway interactions; Population; Positioning Attribute; Public Health Informatics; Puerto Rican; Puerto Rico; Research; Research Personnel; Research Project Grants; Research Support; Resources; Rural Community; Secure; Services; Source; System; Technology; Training; Training Programs; Training and Education; Translational Research; Urban Community; Work; base; bilingualism; biomedical informatics; clinical care; clinical data warehouse; cyber infrastructure; data infrastructure; data mining; data warehouse; design; drug efficacy; electronic data; experimental study; field study; health care delivery; health data; improved; informatics tool; innovation; interdisciplinary approach; medically underserved; monitoring device; population health; programs; recruit; research study; routine care; support tools; tool; translational scientist; volunteer; web portal; web site

Abstract/Summary Our understanding of individual and population health status, including the development of innovative approaches to disease identification and treatment, is increasingly based on the availability and analyses of real- world data (RWD) collected from environments where routine care is provided (e.g., electronic health records (EHRs), claims and billing activities). When consolidated into clinical research data warehouses (CRDWs), RWD become a critical source for medical data mining supporting clinical research/trials, as well as informing healthcare in all facets of medicine. The goal of the Biomedical Informatics, Bioinformatics, and Cyberinfrastructure Enhancement Core (BiBEC) is to strengthen and expand the tools and resources that supply real world data specific to Hispanic populations, and develop programs that prepare skilled informaticians. In addition, BiBEC is committed to increasing knowledge in biomedical informatics, bioinformatics, and health informatics so that clinicians as well as clinical and translational researchers are informed consumer of said services, understanding their applications in both clinical care and research environments. The central hypothesis of the aims presented here is that informatics tools, and the necessary resources to fully utilize these tools, can advance health and healthcare at all nodes along the clinical and translational research pathway. The specific aims of BiBEC are to: 1) strengthen and expand existing health data infrastructure to improve clinical care and best practices (electronic health records/clinical research data warehouse), 2) enhance the availability and recruitment opportunities of Puerto Rican and other Hispanic populations into clinical and translational research studies using technology-based innovations, and 3) develop training for clinicians and clinical and translational researchers which will enable their use and application of available biomedical, bioinformatic, and health informatics-related data and technologies. The innovation of BiBEC includes: 1) an operational, secure clinical research data warehouse; 2) bilingual website that proactively supports the promotion of clinical trial opportunities, with a community-facing web portal, where individuals may register as a volunteer in clinical trials; 3) FISMA and HIPAA-compliant web-based data collection tools; and 4) training and continuing education in biomedical informatics, health informatics, and bioinformatics that helps clinicians and clinical researchers be informed consumers of biomedical and bioinformatics information and tools.

摘要/摘要 我们对个人和人口健康状况的理解，包括创新的发展 疾病鉴定和治疗的方法越来越基于实际的可用性和分析 从提供常规护理的环境中收集的世界数据（RWD）（例如，电子健康记录 （EHR），索赔和计费活动）。当合并到临床研究数据仓库（CRDWS）中时，RWD 成为支持临床研究/试验的医疗数据挖掘的关键来源，并告知 医学各个方面的医疗保健。生物医学信息学，生物信息学和 网络基础设施增强核心（BIBEC）是增强和扩展提供的工具和资源 针对西班牙裔人群的现实世界数据，并开发了准备熟练信息家的计划。在 此外，比贝克致力于增加有关生物医学信息学，生物信息学和健康的知识 信息学，以便向临床医生以及临床和翻译研究人员告知消费者。 服务，了解他们在临床护理和研究环境中的应用。中央 这里提出的目标的假设是信息学工具以及充分利用这些的必要资源 工具可以在临床和转化研究途径沿所有节点的所有节点中促进健康和医疗保健。这 比贝克的具体目标是：1）加强和扩大现有的健康数据基础设施以改善临床 护理和最佳实践（电子健康记录/临床研究数据仓库），2）增强可用性 波多黎各人和其他西班牙裔人口招募机会 使用基于技术创新的研究，以及3）为临床医生和临床医生开发培训 翻译研究人员将使他们能够使用和应用可用的生物医学，生物信息学， 以及与健康信息相关的数据和技术。比贝克的创新包括：1）运营， 安全临床研究数据仓库； 2）主动支持促进临床的双语网站 审判机会和面向社区的Web门户网站，个人可以在临床上注册为志愿者 试验； 3）FISMA和符合HIPAA的基于Web的数据收集工具； 4）培训和继续教育 在生物医学信息学，健康信息学和生物信息学方面，可以帮助临床医生和临床研究人员 为消费者提供了生物医学和生物信息学信息和工具。