Prevention of Substance Use in At-risk Students: A Family-centered Web Program

预防高危学生的药物使用：以家庭为中心的网络计划

• 批准号: 10258908
• 负责人: ELIZABETH A STORMSHAK
• 金额: $ 121.32万
• 依托单位: UNIVERSITY OF OREGON
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-12-01 至 2022-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10258908
• 关键词: 2019-nCoV; AIDS/HIV problem; Address; Adopted; Adoption; American; CLIA certified; COVID-19; COVID-19 testing; COVID-19 vaccine; Centers for Disease Control and Prevention (U.S.); Cessation of life; Client; Communities; Contracts; County; Data; Data Collection; Diagnostic tests; Discrimination; Disease; Equipment and Supplies; Exposure to; Family; General Population; Goals; HIV; HIV Infections; HIV/HCV; Health; Healthcare Systems; Hospitals; Hygiene; Immunocompromised Host; Individual; Infrastructure; Injecting drug user; Internet; Interruption; Intervention; Laboratories; Laboratory Personnel; Leadership; Link; Medical; Misinformation; Molecular; Motivation; Needle-Exchange Programs; Oregon; Outcome; Pilot Projects; Population; Prevalence; Preventive; Procedures; Process; Program Acceptability; Protocols documentation; Public Health; Quarantine; RADx Underserved Populations; Recording of previous events; Reporting; Research; Resources; Risk; Risk Factors; SARS-CoV-2 exposure; SARS-CoV-2 transmission; Series; Services; Social Network; Source; Specimen; Stigmatization; Students; Symptoms; System; Testing; Time; Trust; Tuberculosis; Underserved Population; Universities; Vaccination; Vaccines; Viral hepatitis; Virus; Vulnerable Populations; base; checkup examination; design; experience; follow-up; health care availability; health care service; housing instability; implementation barriers; implementation facilitators; implementation framework; implementation outcomes; intervention effect; laboratory experience; motivational enhancement therapy; pandemic disease; point of care; prevent; programs; sample collection; scale up; service delivery; service utilization; severe COVID-19; social health determinants; social vulnerability; substance use prevention; testing access; testing services; testing uptake; transmission process; volunteer

PROJECT SUMMARY People who inject drugs (PWIDs) are a socially vulnerable population and are exposed to risk factors including unstable housing and underlying medical conditions such as human immunodeficiency virus (HIV), tuberculosis (TB), and viral hepatitis that put them at increased risk for severe COVID-19 symptoms, including death. PWIDs also experience barriers such as a history of stigmatization and discrimination by health care systems and exposure to misinformation about testing that reduces access to health care services and testing. Because timely receipt of services relative to symptoms onset is critical for positive health outcomes and to reduce SARS-CoV-2 transmission, lack of testing has significant implications for PWID, highlighting an urgent need to increase testing uptake among this population. Despite this, PWIDs have been an underserved population in the context of the current pandemic; thus, little is known about the prevalence of COVID-19 and the acceptability and possible reach of testing for COVID-19 among PWIDs. To address this gap, this study leverages a current partnership with HIV Alliance (HIVA) in Oregon and our Community and Scientific Advisory Board to support implementation and sustainability of a COVID-19 testing program. Specifically, we will use community-based participatory approaches to develop, implement, and evaluate a COVID-19 testing program offered through HIVA’s Syringe Services Programs (SSP), a natural point of care for PWIDs. Moreover, SSPs may offer a natural venue for dissemination and delivery of a vaccine, once available. The COVID-19 testing program will include procedures for sample collection, transmission of specimens to the University of Oregon CLIA-certified laboratory, and results reporting. For aim 1, we will assess the testing program utilization. For aim 2, we will develop and test a brief motivational enhancement intervention to optimize testing utilization among PWIDs. Using an interrupted time series design, we will evaluate intervention effects on utilization of COVID-19 testing resources. For aim 3, we will collect data from syringe exchange staff and key volunteers on program acceptability, feasibility, appropriateness, adoption, and implementation barriers and facilitators related to the testing program and intervention. The current project has the potential to enhance COVID-19 testing access and reach among a significantly underserved population who experience multiple risks that make it difficult to prevent SARS-CoV-2 exposure and transmission and who are at increased risk for severe COVID-19 symptoms, if they were to contract the disease.

项目摘要 注射毒品（PWID）的人是一个社会脆弱的人口，面临着风险因素 不稳定的住房和潜在的医疗状况，例如人类免疫缺陷病毒（HIV）， 结核病（TB）和病毒性肝炎，使它们患有严重的Covid-19症状的风险增加，包括 死亡。 PWIDS还经历了诸如医疗保健污名和歧视史之类的障碍 系统和关于测试的未经信息的暴露，以减少获得医疗服务和测试的访问。 因为及时接收相对于症状发作的服务对于积极的健康结果至关重要 减少SARS-COV-2传输，缺乏测试对PWID具有重大影响，突显了紧急的 需要增加该人群的测试吸收。尽管如此，pwids一直是服务不足的 在当前大流行的背景下的人口；因此，关于COVID-19的患病率和 PWID中COVID-19的可接受性和可能范围。为了解决这一差距，这项研究 利用与俄勒冈州艾滋病毒联盟（HIVA）以及我们的社区和科学咨询的当前合作伙伴关系 董事会支持COVID-19测试计划的实施和可持续性。具体来说，我们将使用 基于社区的参与方法来开发，实施和评估COVID-19测试计划 通过Hiva的注射器服务计划（SSP）提供，这是PWID的自然护理点。此外，SSP 一旦可用，可能会提供自然的场所，用于传播和输送疫苗。 COVID-19测试 计划将包括采样的程序，将标本传输到俄勒冈大学 获得CLIA认证的实验室和结果报告。对于AIM 1，我们将评估测试计划的利用率。为了 AIM 2，我们将开发和测试简短的动机增强干预措施，以优化测试利用率 在pwids中。使用中断的时间序列设计，我们将评估干预对利用的影响 COVID-19测试资源。对于AIM 3，我们将从注射器交换人员和主要志愿者那里收集数据 计划可接受性，可行性，适当性，采用和实施障碍和促进者 与测试计划和干预有关。当前的项目有可能增强Covid-19 测试访问和到达的人群中，遇到多种风险的人口不足 难以防止SARS-COV-2暴露和传播，并且患有严重的风险增加 Covid-19症状，如果他们染上了这种疾病。