Development of high affinity novel Fluor Mop adsorbent for the rapid removal of perfluorinated chemicals from groundwater

开发高亲和力新型 Fluor Mop 吸附剂，用于快速去除地下水中的全氟化学品

• 批准号: 10259234
• 负责人: Alexa May
• 金额: $ 15.35万
• 依托单位: WEAVER LABS, LLC
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-06 至 2022-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10259234
• 关键词: Adsorption; Affinity; Air; Animals; Binding; Blood; Carbon; Carbon ion; Carpet; Centers for Disease Control and Prevention (U.S.); Chemicals; Cholesterol; Communities; Congenital Abnormality; Data; Development; Disease; Effectiveness; Environment; Enzymes; Equilibrium; Excision; Film; Filtration; Food Packaging; Furniture; Future; Goals; Health; Hepatotoxicity; High temperature of physical object; Human; Human Milk; Human body; Hydrogen Bonding; Immune; Immune system; Individual; Industry; Infant; Inferior; Ion Exchange Resins; Kinetics; Laboratories; Lead; Link; Liver; Location; Malignant Neoplasms; Military Personnel; Modification; Municipalities; Names; Natural regeneration; Nature; Osmosis; Outcome; Performance; Phase; Pilot Projects; Plant Resins; Plants; Poison; Poly-fluoroalkyl substances; Population; Positioning Attribute; Predisposition; Process; Property; Public Health; Research; Risk; Sampling; Seminal; Silicon Dioxide; Soil; Solid; Solvents; Steam; Sulfonic Acids; Sunscreening Agents; Surface; System; Techniques; Technology; Testing; Thyroid Diseases; Time; Translating; United States Environmental Protection Agency; Water; Water Purification; aqueous; base; cancer type; consumer product; contaminated water; cost; cost effective; design; drinking water; experimental study; ground water; improved; insight; member; novel; organic contaminant; perfluorooctane sulfonate; perfluorooctanoic acid; phase 2 study; pollutant; public drinking; remediation; response; screening; time use; water treatment

Perfluorinated alkyl substances (PFAS), nicknamed “Forever Chemicals”, are extensively used in industries and firefighting applications as a component of aqueous film forming foams (AFFFs). Because members of this class of chemicals are persistent, they are prevalent in nature and are detected across the globe in water, air, soil, plants, animals, and even in human milk and blood. They are toxic to human health, and even at lower levels are linked to developmental effects in infants, liver toxicity, increased risk of certain types of cancer, immune system impacts, thyroid disease, and many other health issues. Therefore the U.S. Environmental Protection Agency (USEPA) has recently set health advisories level for two PFAS, perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) at 70 ng/L individually or combined. In response to the need for remediation of PFAS contaminated water many technologies have been scrutinized, including adsorption-based remediation technology. Most notably, the use of granular activated carbon (GAC) and ion exchange resins sorbents. Among these, GAC is the most widely accepted and commonly used treatment technology for PFAS contaminated groundwater and drinking water. However, GAC has many drawbacks for example its susceptibility to fouling by natural organic matter, expensive intensive high energy regeneration process, and inferior in removal of short chain PFAS. Additionally, since GAC is not designed for PFAS adsorption it displays only low affinity towards PFAS, thus, it requires significantly large amounts of GAC to achieve the desired PFAS levels. Therefore, there is a need for adsorbents that are specifically designed for the PFOA/PFOS removal in efficient, cost-effective, and recyclable manner. In ongoing research, Weaver Labs has designed novel PFOA/PFOS specific adsorbents that leverage an advanced solid support platform. In the preliminary adsorption studies, the adsorbent demonstrated superior PFOA/PFOS affinity compared to GAC technology using PFOA/PFOS contaminated real world groundwater. Weaver labs’ long-term goal for this project is to develop commercial PFAS specific adsorbent filter that is highly efficient, effective, recyclable and economical which can be utilized to purify PFAS contaminated water. Ultimately, it would allow pure water to be delivered to the public, thus decreasing the health risk associated with these chemicals. To meet the long-term goal this proposal’s objective is to develop and screen novel adsorbents, carry out the required kinetic adsorption study experiments, and optimize its regeneration and reuse. The completion of proposed study will position us for phase II studies, including a rapid small-scale column study, and eventual pilot study.

绰号为“永远的化学物质”的全氟烷基物质（PFA）广泛用于行业 和消防应用是形成泡沫（AFFFS）的水膜的组成部分。因为成员 在这类化学物质中，它们持续存在，它们在本质上很普遍，并且在全球范围内被发现 水，空气，土壤，植物，动物，甚至在人牛奶和血液中。它们对人类健康有毒，并且 即使在较低的水平也与婴儿，肝毒性的发育影响有关，某些人的风险增加 癌症的类型，免疫系统影响，甲状腺疾病以及许多其他健康问题。 因此美国 环境保护局（USEPA）最近设定了两个PFA的健康咨询水平， 全氟辛酸（PFOA）和全氟辛烷磺酸盐（PFO）分别或合并为70 ng/l。 为了应对对PFA污染水的补救的需求，许多技术已经是 经过审查，包括基于吸附的补救技术。最值得注意的是，使用颗粒 碳（GAC）和离子交换响应分类。其中，GAC是最广泛接受的， 普通使用PFA的治疗技术，污染了地下水和饮用水。然而， GAC有许多缺点，例如它对自然有机物污染的敏感性，昂贵 密集的高能量再生过程，在去除短链PFA的情况下较低。此外，自从 GAC不是为PFA的吸附而设计的，它仅显示对PFA的低亲和力，因此，它需要 大量的GAC达到所需的PFA水平。因此，需要 专门为PFOA/PFO设计而设计的吸附剂，以高效，具有成本效益和 可回收的方式。 在正在进行的研究中，Weaver Labs设计了新型的PFOA/PFO特定的吸附剂，以利用 高级固体支持平台。在初步的吸附研究中，吸附剂表现出优质 与GAC技术相比，PFOA/PFO亲和力使用PFOA/PFO污染了现实世界 地下水。 Weaver Labs这个项目的长期目标是开发特定于商业PFA 高效，有效，可回收且经济的吸附剂过滤器可用于净化 PFA污染了水。最终，它将允许将纯净的水交给公众，从而 降低与这些化学物质相关的健康风险。为了实现这个建议的长期目标 目的是开发和筛选新颖的吸附剂，进行所需的动力学吸附研究 实验，并优化其再生和再利用。拟议研究的完成将使我们定位 对于II期研究，包括快速的小规模列研究和最终的初步研究。