NICHD maternal fetal medicine units network

NICHD母胎医学单位网

基本信息

批准号：
10254471
负责人：
Maged Costantine
金额：
$ 26.98万
依托单位：
OHIO STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1992
资助国家：
美国
起止时间：
1992-04-08 至 2025-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10254471
关键词：
Accounting Address Adherence Alloimmunization Ambulatory Care Facilities American Beds Bioinformatics Birth COVID-19 pandemic Caring Cesarean section Child Cities Clinic Clinic Visits Clinical Clinical Research Clinical Trials Collaborations Computerized Medical Record Data Data Analyses Data Coordinating Center Department chair Diabetes Mellitus Discipline of obstetrics Enrollment Ensure Environment Epidemiologist Faculty Funding Funding Opportunities Goals Grant Hepatitis C Transmission Hepatitis C virus Hospital Administrators Hospitalization Hospitals Human Hypertension Image Infant Mortality Information Systems Infrastructure Institution Investments Laboratories Leadership Letters Link Maternal-Fetal Medicine Units Network Maternal-fetal medicine Medical center Mission Mothers National Heart, Lung, and Blood Institute National Institute of Child Health and Human Development Neonatal Neonatal Intensive Care Units Neonatology Network-based Notification Nulliparity Nurse Administrator Nurses Ohio Outpatients Participant Pathology Patients Pediatric Hospitals Performance Perinatal Perinatal Epidemiology Perinatal mortality demographics Pharmacology Physicians Policies Population Population Heterogeneity Positioning Attribute Postpartum Period Pravastatin Pre-Eclampsia Pregnancy Outcome Pregnancy in Diabetics Premature Birth Prenatal care Prevention Principal Investigator Productivity Protocols documentation Provider Publications Research Research Design Research Infrastructure Research Personnel Resources Risk Services Site Structure System Translational Research Trial of Labor Trust U-Series Cooperative Agreements Universities Vertical Disease Transmission Woman antenatal base clinical care clinical center clinical investigation community involvement data quality ethnic diversity experience faculty research fetal follow-up high risk improved infant morbidity innovation intrapartum member opioid use disorder premature prenatal prevent programs protocol development racial diversity recruit response screening statistics

项目摘要

ABSTRACT This proposal describes the application of The Ohio State University (OSU) Center for continued participation in the Eunice Kennedy Shriver NICHD Maternal Fetal Medicine Units (MFMU) Network. The current application describes our team, environment and resources to meet the objectives of the Network. Since 1992, the OSU Center has demonstrated a strong performance and experience in conducting clinical and translational research based on excellent infrastructure and institutional support. We developed a strong research team led by Maged Costantine, MD who was recruited to the OSU Wexner Medical Center in 2019, as a Division Director for Maternal Fetal Medicine and Principal Investigator for the MFMU Network Center, and Mark Landon, MD who serves as Chair for the Department of OG/GYN and Alternate PI. In addition to productivity in the MFMU Network, both the PI and alternate PI, bring extensive experience in study design, recruitment, data analysis, and publications. The OSU Network will recruit study participants from diverse populations at 3 medical centers with a combined total of more than 15,000 annual births, many of them are high-risk, and the majority receiving prenatal care at the three systems. Our Center Nurse Coordinator, Anna Bartholomew, MPH, RN, BSN, CCRP, leads a large group of faculty & research staff capable of recruiting and retaining patients in the setting of an excellent research organization enhanced by 29 years of experience in the MFMU Network, participation in the NICHD Nulliparous Network, and memberships in the North American Fetal Treatment Network, and Ohio Perinatal Research Network (OPRN). We benefit from a robust bioinformatics structure and versatile Electronic Medical Record System (EMR) that captures antepartum, intrapartum, and postpartum data online and is readily available to authorized research personnel for query as well as automatic notification, an extraordinary group of obstetrical sonographers, perinatal epidemiologists, and a mature research infrastructure supported by a CTSA grant shared with Nationwide Children’s Hospital. Our satellite sites, Miami Valley Hospital in Dayton and Good Samaritan Hospital in Cincinnati, have an outstanding record of recruitment in the most recent Network cycle, well-established research culture, and ambitious goals for MFMU Network participation. Our partnership and strong collaboration with Neonatology at Nationwide Children’s Hospital in clinical care and research, Pathology and Clinical Laboratory add strengths to our application. We look forward to continuing our tradition of service, strong performance, and innovation in the next cycle of the NICHD MFMU Network. We accept the RFA’s capitation and participatory stipulations and stand ready to achieve the goals of the Network in completion of the ongoing studies in a collaborative way across all research centers.

抽象的该提案描述了俄亥俄州立大学 (OSU) 中心持续参与的申请尤尼斯·肯尼迪·施赖弗 (Eunice Kennedy Shriver) NICHD 母胎医学中心 (MFMU) 网络中的当前应用程序。描述了我们自 1992 年以来实现网络目标的团队、环境和资源。中心在开展临床和转化方面表现出强大的表现和经验研究基于优良的基础设施和机构支持，我们培养了一支强大的研究团队。由 Maged Costantine 医学博士担任，他于 2019 年被招募到 OSU Wexner 医疗中心，作为一名部门母胎医学主任兼 MFMU 网络中心首席研究员 Mark Landon 医学博士，除了提高生产力外，还担任 OG/GYN 和候补 PI 部门的主席。 MFMU 网络（无论是 PI 还是候补 PI）在研究设计、招募、数据方面带来了丰富的经验分析和出版物。 OSU 网络将于 3 日从不同人群中招募研究参与者。每年总共有超过 15,000 名新生儿出生的医疗中心，其中许多是高风险的，而且大多数人在我们的中心护士协调员 Anna Bartholomew 接受产前护理。 MPH、RN、BSN、CCRP，领导着一大批能够招聘和保留人才的教职员工和研究人员 MFMU 29 年的经验增强了优秀研究组织的环境，为患者提供帮助网络、NICHD 未产儿网络的参与以及北美胎儿网络的会员资格治疗网络和俄亥俄州围产期研究网络 (OPRN) 我们受益于强大的生物信息学。结构和多功能电子病历系统 (EMR)，可捕获产前、产中和产后情况在线产后数据，可供授权研究人员查询并自动通知，由产科超声医师、围产期流行病学家和成熟的专家组成的非凡团队我们的卫星由 CTSA 拨款支持的研究基础设施。代顿的迈阿密谷医院和辛辛那提的好撒玛利亚医院拥有出色的记录最近网络周期中的招聘数量、完善的研究文化以及雄心勃勃的目标 MFMU 网络参与。我们与 Nationwide 新生儿科的合作伙伴关系和强有力的合作。儿童医院的临床护理和研究、病理学和临床实验室为我们增添了优势我们期待在该领域继续我们的服务传统、强大的性能和创新。我们接受 RFA 的按人头付费和参与性规定，并且准备好以协作方式完成正在进行的研究，以实现网络的目标遍及所有研究中心。