NICHD maternal fetal medicine units network

NICHD母胎医学单位网

基本信息

批准号：
10254471
负责人：
Maged Costantine
金额：
$ 26.98万
依托单位：
OHIO STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1992
资助国家：
美国
起止时间：
1992-04-08 至 2025-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10254471
关键词：
Accounting Address Adherence Alloimmunization Ambulatory Care Facilities American Beds Bioinformatics Birth COVID-19 pandemic Caring Cesarean section Child Cities Clinic Clinic Visits Clinical Clinical Research Clinical Trials Collaborations Computerized Medical Record Data Data Analyses Data Coordinating Center Department chair Diabetes Mellitus Discipline of obstetrics Enrollment Ensure Environment Epidemiologist Faculty Funding Funding Opportunities Goals Grant Hepatitis C Transmission Hepatitis C virus Hospital Administrators Hospitalization Hospitals Human Hypertension Image Infant Mortality Information Systems Infrastructure Institution Investments Laboratories Leadership Letters Link Maternal-Fetal Medicine Units Network Maternal-fetal medicine Medical center Mission Mothers National Heart, Lung, and Blood Institute National Institute of Child Health and Human Development Neonatal Neonatal Intensive Care Units Neonatology Network-based Notification Nulliparity Nurse Administrator Nurses Ohio Outpatients Participant Pathology Patients Pediatric Hospitals Performance Perinatal Perinatal Epidemiology Perinatal mortality demographics Pharmacology Physicians Policies Population Population Heterogeneity Positioning Attribute Postpartum Period Pravastatin Pre-Eclampsia Pregnancy Outcome Pregnancy in Diabetics Premature Birth Prenatal care Prevention Principal Investigator Productivity Protocols documentation Provider Publications Research Research Design Research Infrastructure Research Personnel Resources Risk Services Site Structure System Translational Research Trial of Labor Trust U-Series Cooperative Agreements Universities Vertical Disease Transmission Woman antenatal base clinical care clinical center clinical investigation community involvement data quality ethnic diversity experience faculty research fetal follow-up high risk improved infant morbidity innovation intrapartum member opioid use disorder premature prenatal prevent programs protocol development racial diversity recruit response screening statistics

项目摘要

ABSTRACT This proposal describes the application of The Ohio State University (OSU) Center for continued participation in the Eunice Kennedy Shriver NICHD Maternal Fetal Medicine Units (MFMU) Network. The current application describes our team, environment and resources to meet the objectives of the Network. Since 1992, the OSU Center has demonstrated a strong performance and experience in conducting clinical and translational research based on excellent infrastructure and institutional support. We developed a strong research team led by Maged Costantine, MD who was recruited to the OSU Wexner Medical Center in 2019, as a Division Director for Maternal Fetal Medicine and Principal Investigator for the MFMU Network Center, and Mark Landon, MD who serves as Chair for the Department of OG/GYN and Alternate PI. In addition to productivity in the MFMU Network, both the PI and alternate PI, bring extensive experience in study design, recruitment, data analysis, and publications. The OSU Network will recruit study participants from diverse populations at 3 medical centers with a combined total of more than 15,000 annual births, many of them are high-risk, and the majority receiving prenatal care at the three systems. Our Center Nurse Coordinator, Anna Bartholomew, MPH, RN, BSN, CCRP, leads a large group of faculty & research staff capable of recruiting and retaining patients in the setting of an excellent research organization enhanced by 29 years of experience in the MFMU Network, participation in the NICHD Nulliparous Network, and memberships in the North American Fetal Treatment Network, and Ohio Perinatal Research Network (OPRN). We benefit from a robust bioinformatics structure and versatile Electronic Medical Record System (EMR) that captures antepartum, intrapartum, and postpartum data online and is readily available to authorized research personnel for query as well as automatic notification, an extraordinary group of obstetrical sonographers, perinatal epidemiologists, and a mature research infrastructure supported by a CTSA grant shared with Nationwide Children’s Hospital. Our satellite sites, Miami Valley Hospital in Dayton and Good Samaritan Hospital in Cincinnati, have an outstanding record of recruitment in the most recent Network cycle, well-established research culture, and ambitious goals for MFMU Network participation. Our partnership and strong collaboration with Neonatology at Nationwide Children’s Hospital in clinical care and research, Pathology and Clinical Laboratory add strengths to our application. We look forward to continuing our tradition of service, strong performance, and innovation in the next cycle of the NICHD MFMU Network. We accept the RFA’s capitation and participatory stipulations and stand ready to achieve the goals of the Network in completion of the ongoing studies in a collaborative way across all research centers.

抽象的该提案描述了俄亥俄州立大学（OSU）中心继续参与的应用在Eunice Kennedy Shriver Nichd母体胎儿医学单位（MFMU）网络中。当前的应用程序描述我们的团队，环境和资源以满足网络的目标。自1992年以来，OSU 中心在进行临床和翻译方面表现出了良好的表现和经验基于出色的基础设施和机构支持的研究。我们建立了一个强大的研究团队领导由医学博士Maged Costantine撰写，他于2019年被招募到OSU Wexner医疗中心孕产妇胎儿医学主任和MFMU网络中心的首席研究员和马克马里兰州兰登（Landon）担任OG/Gyn和替代PI部门的主席。除了生产力 PI和替代PI的MFMU网络带来了研究设计，招聘，数据的丰富经验分析和出版物。 OSU网络将在3岁时招募来自潜水员人群的研究参与者总共有15,000多名年龄的医疗中心，其中许多是高风险的，多数在三个系统中接受产前护理。我们的中心护士协调员Anna Bartholomew， MPH，RN，BSN，CCRP领导了一大批能够招募和保留的教职员工和研究人员在MFMU的29年经验中，在优秀研究组织的情况下，患者增强了网络，参与NICHD无效网络以及北美胎儿的会员资格治疗网络和俄亥俄州围产期研究网络（OPRN）。我们从强大的生物信息学中受益结构和多功能电子记录系统（EMR），可捕获Antapartum，Interapartum和产后数据在线数据，可用于授权的研究人员进行查询以及自动通知，一群非凡的产科超声参与者，围产期流行病学家和一个成熟的 CTSA赠款与全国儿童医院共享的研究基础设施。我们的卫星网站，代顿的迈阿密谷医院和辛辛那提的好撒玛利亚医院，有着出色的记录在最近的网络周期中招募的招聘，公认的研究文化以及雄心勃勃的目标 MFMU网络参与。我们在全国范围内与新生儿学的伙伴关系和强有力的合作临床护理和研究，病理和临床实验室的儿童医院为我们的应用。我们期待继续我们的服务传统，强大的绩效和创新 NICHD MFMU网络的下一个周期。我们接受RFA的资本化和参与规定以及准备以协作的方式完成正在进行的研究完成网络的目标在所有研究中心。