Next-generation sequencing of candidate ovarian tumour suppressor genes

候选卵巢肿瘤抑制基因的下一代测序

• 批准号: nhmrc : 628733
• 负责人: Dr Kylie Gorringe
• 金额: $ 6.79万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/next-generation-sequencing-suppressor-genes/97108
• 关键词: Next; generation; sequencing; candidate; ovarian

In Australia in 2001 there were approximately 1300 new cases of ovarian cancer. Survival of ovarian cancer is very poor and current treatments inadequate. To develop more effective treatments we need to understand the molecular events that cause ovarian cancer. Some genes are inactivated by loss of a copy or mutation. We aim to find these genes using new DNA sequencing techniques.

2001 年澳大利亚大约有 1300 例新发卵巢癌病例。卵巢癌的生存率非常低，并且目前的治疗方法不足。为了开发更有效的治疗方法，我们需要了解导致卵巢癌的分子事件。有些基因因拷贝丢失或突变而失活。我们的目标是使用新的 DNA 测序技术找到这些基因。