Administration and Biostatistics Core

行政和生物统计学核心

• 批准号: 10089336
• 负责人: MACRAE F LINTON
• 金额: $ 19.03万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-06-01 至 2025-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10089336
• 关键词: Animals; Award; Bioinformatics; Biometry; Biostatistics Core; Budgets; Code; Communication; Data Analyses; Documentation; Ensure; Equipment; Expenditure; Experimental Designs; Grant; High Density Lipoproteins; Institutional Policy; Methods; Policies; Procedures; Reagent; Reporting; Reproducibility; Research Personnel; Seeds; Services; Supervision; Travel; Untranslated RNA; Validation; Work; human disease; human subject; meetings; model development; simulation

The purpose of the Administrative and Biostatistics Core (Core A) is to coordinate the administrative and fiscal activities of the PPG, to provide biostatistics support for all of the Projects, and to ensure rigorous experimental design and data analysis for all the Projects. Dr. Linton will provide oversight for all functions of Core A. Mr. Nicholas Jenkins, Grants Manager, will work closely with Dr. Linton to provide fiscal oversight and management of the budgetary aspects of the PPG’s Projects and Cores, including compliance with institutional policy and implementation of grant policy for post award management. Mr. Jenkins will assist with budgets related to grant submissions, including competing and noncompeting renewals. Ms. Lawrence will oversee the financial aspects of the administration of the budget. She will supervise and coordinate communication with the Grants Manager and the Administrative Officer. Maria Peng, Administrative Officer, will prepare monthly budget statements for the Projects and Cores for the Investigators. She will be responsible for PPG reports and administration of finances for the service Cores and the Projects. Ms. Lawrence and Ms. Bartkus, the administrative assistant, will be jointly responsible for generating purchase orders for equipment and reagents for all of the PPG Projects and Cores, and for expenditure reconciliation. Ms. Bartkus will also help with arranging the monthly meetings of PPG Project Leaders, investigators and Core Leaders, organize seminars, meetings with advisors and handle PPG related travel. She will ensure that all human subject and animal use documentation is current. The Biostatistics portion of Core A will provide statistical expertise for all projects and investigators to ensure rigor and reproducibility for all PPG projects. Drs. Ye and Du will continue to work closely with project leaders and will be available to all PPG investigators to provide state-of-the-art statistical support. To ensure statistical reproducibility, for each PPG-associated analysis performed, a statistical report in HTML or PDF format will be generated, which will document the R programming codes and any simulation seeds used in the analysis. Additionally, all model development procedures will be internally validated using cross-validation or bootstrap methods. The Biostatistics Core supports all 4 Projects. Bioinformatics support will be provided in Core D: The Non-Coding RNA and Bioinformatics Core.

行政和生物统计学核心（核心A）的目的是协调行政和财政 PPG的活动，为所有项目提供生物统计学支持，并确保严格的实验 所有项目的设计和数据分析。 Linton博士将为Core A的所有功能提供监督。 赠款经理尼古拉斯·詹金斯（Nicholas Jenkins）将与林顿博士紧密合作，提供财政监督和管理 PPG项目和核心的预算方面，包括遵守机构政策和 实施授予奖励管理的赠款政策。詹金斯先生将协助与赠款有关的预算 提交，包括竞争和非竞争续订。劳伦斯女士将监督财务方面 预算管理。她将监督和协调赠款经理的沟通 和行政官。行政官员玛丽亚·彭（Maria Peng）将为每月预算声明准备 调查人员的项目和核心。她将负责PPG报告和管理 服务核心和项目的财务。劳伦斯女士和行政助理巴特库斯女士将 负责为所有PPG项目的设备和试剂生成采购订单 核心和支出和解。 Bartkus女士还将帮助安排PPG的每月会议 项目负责人，调查人员和核心领导者，组织半手，与顾问会议并处理PPG 相关旅行。她将确保所有人类主体和动物使用文档都是最新的。生物统计学 核心A的一部分将为所有项目和调查人员提供统计专业知识，以确保严格和 所有PPG项目的可重复性。博士。 Ye和Du将继续与项目负责人紧密合作，并将 所有PPG调查人员都可以提供最先进的统计支持。确保统计 重现性，对于进行的每种PPG相关分析，HTML或PDF格式的统计报告将为 生成的，它将记录R编程代码和分析中使用的任何模拟种子。 此外，所有模型开发程序将在内部使用交叉验证或自举验证 方法。生物统计学核心支持所有4个项目。核心D将提供生物信息学支持： 非编码RNA和生物信息学核心。