Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS)

乔治城-霍华德大学临床与转化科学中心 (GHUCCTS)

• 批准号: 10086545
• 负责人: THOMAS A MELLMAN
• 金额: $ 371.68万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-28 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10086545
• 关键词: Academia; Achievement; Address; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Collaborations; Communities; Computing Methodologies; Cultural Backgrounds; Degree program; Disabled Persons; Discipline; District of Columbia; Elderly; Enrollment; Faculty; Funding; Future; Goals; Grant; Health; Health Professional; Home environment; Informatics; Infrastructure; Institution; Interdisciplinary Study; Investigation; Laboratories; Leadership; Location; Longevity; Master of Science; Medical center; Mentorship; Minority-Serving Institution; Mission; Modeling; Multi-Institutional Clinical Trial; Patient Care; Population; Process; Public Health; Research; Research Institute; Research Personnel; Research Training; Risk; Role; Science; Scientist; Speed; Students; System; TNFSF15 gene; Training; Training Programs; Training Support; Training and Education; Translational Research; Translations; Underrepresented Groups; Underserved Population; United States Department of Veterans Affairs; Universities; Veterans; Washington; analytical method; base; career; career development; catalyst; clinical center; design; health disparity; improved; innovation; inter-institutional; interdisciplinary collaboration; member; new technology; programs; racial and ethnic; racial diversity; research study; translational scientist

The Georgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS) is a primary partnership of Georgetown University (GU) and Howard University (HU), with 3 affiliated institutions: MedStar Health Research Institute (MHRI), Oak Ridge National Laboratory (ORNL), and the Washington DC Veterans Affairs Medical Center (DCVAMC). This application is for our second competitive renewal. The specific aims of GHUCCTS are presently: 1) To continue to improve the infrastructure that supports high quality, interdisciplinary clinical and translational research, both via inter-institutional collaborations among GHUCCTS institutions as well as multicenter clinical trials across the national CTSA consortium, with increasing efficiency; 2) To further establish GHUCCTS as a model of inter-institutional collaboration that leverages the strengths and attributes of its diverse participating institutions in order to maintain GHUCCTS as a regional CTSA hub with unique and synergistic strengths; 3) To leverage our location, expertise and the co-leadership of a minority-serving institution to design, implement and disseminate clinical and translational research that will have a high impact on populations with health disparities, particularly underserved groups in our communities who have been historically under- represented in clinical research studies, including people from diverse racial, ethnic, and cultural backgrounds, people with disabilities, older adults and Veterans; 4) To continue to provide new vibrant and innovative educational programs for multiple levels of trainees, faculty and staff that promote principles of team science, and to provide the high quality career development training and support for the clinical and translational investigators of the future; and 5) To continue to apply and develop innovative analytical and computational methods to speed and enhance translation. In achieving these specific aims and their corresponding strategic goals we will draw from and contribute to the collective efforts and mission of the National Center for Advancing Translational Science (NCATS), and the national CTSA consortium. In the first 8 years as a funded CTSA program, GHUCCTS evolved into a fully functional multi-institutional center that has transformed CTR across each of the GHUCCTS member institutions with growing inter-institutional and inter-disciplinary collaboration and mentorship. Enrollment of under-represented groups is high in our research studies, and have increased to levels that more than double the national CTSA hub mean in our training programs. We have designed a new core in collaboration with ORNL that leverages their novel technologies to address environmental determinants of health risk in the District of Columbia. We will continue designing and refining innovative GHUCCTS programs to train the clinical and translational scientists and leaders of the future, and to disseminate these educational programs across the full spectrum of students, trainees and healthcare professionals at our GHUCCTS institutions and the national CTSA network.

乔治敦 - 霍纳德大学临床和转化科学中心（GHUCCTS）是主要的 乔治敦大学（GU）和霍华德大学（HU）的合作伙伴关系，与3个附属机构：MEDSTAR 卫生研究所（MHRI），橡树岭国家实验室（ORNL）和华盛顿特区退伍军人 事务医疗中心（DCVAMC）。此应用程序是我们的第二个竞争续约。具体目的 GHUCCT目前是：1）继续改善支持高质量，跨学科的基础设施 临床和转化研究，包括GHUCCT机构之间的机构间合作 随着全国CTSA财团的多中心临床试验，效率提高； 2）进一步建立 GHUCCT是一种机构间合作的模型，利用其多样的优势和属性 参与机构为了将GHUCCT保持为具有独特和协同作用的区域CTSA枢纽 优势； 3）利用我们的位置，专业知识和少数派服务机构的共同领导权来设计， 实施和传播临床和转化研究，对人群的影响很大 健康差异，尤其是我们社区中服务不足的群体，这些群体历来不足 在临床研究中代表，包括来自不同种族，种族和文化背景的人们 残疾人，老年人和退伍军人； 4）继续提供新的充满活力和创新性 针对促进团队科学原则的多个学员，教职员工的教育计划， 为高质量的职业发展培训和支持 未来； 5）继续应用和开发创新的分析和计算方法来加快和 增强翻译。在实现这些具体目标及其相应的战略目标时，我们将从 并为国家推进转化科学中心的集体努力和使命做出贡献 （NCAT）和国家CTSA财团。 在作为资助CTSA计划的头8年中，Ghuccts演变成一个功能齐全的多机构中心 这使CTR改变了每个GHUCCTS成员机构的机构间和 跨学科的合作与指导。我们的研究中，代表性不足的群体的入学率很高 研究，并增加了水平，这是我们培训中国家CTSA中心的两倍以上 程序。我们设计了一个与ORNL合作的新核心 解决哥伦比亚特区健康风险的环境决定因素。我们将继续设计和 精炼创新的GHUCCTS计划，以培训未来的临床和转化科学家和领导者， 并在各种学生，学员和医疗保健方面传播这些教育计划 我们的GHUCCT机构和国家CTSA网络的专业人士。