Increasing the Social Science Impact of Biomedical Research

增加生物医学研究的社会科学影响

• 批准号: 10089675
• 负责人: Luc Teyton
• 金额: $ 3.41万
• 依托单位: SCRIPPS RESEARCH INSTITUTE, THE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10089675
• 关键词: Acute; Address; Basic Science; Biological Sciences; Biomedical Research; California; Clinical; Communities; Competence; Complex; Development; Disease; Doctor of Philosophy; Education; Environmental Impact; Evolution; Health; Healthcare; Human; Institutes; Medical; Mentorship; Methodology; Outcome; Paper; Pathway interactions; Perception; Physicians; Population; Positioning Attribute; Postdoctoral Fellow; Pre-Clinical Model; Process; Publishing; Research; Research Institute; Research Methodology; Research Personnel; Schools; Science; Series; Social Sciences; Students; TNFSF15 gene; Time; Training; Training Programs; Translating; Translational Research; Underrepresented Students; base; college; design; drug development; drug discovery; experience; innovation; insight; medical schools; meetings; multidisciplinary; pre-doctoral; precision medicine; programs; recruit; research study; skills; social; social culture; social health determinants; success; translational medicine

Training Core (TL1) - Abstract The objective of the Scripps Translational Science Institute (STSI) TL1 training program is to give pre- and postdoctoral fellows a unique experience in cutting-edge methodological and analytical approaches aimed at making them efficient in the complex arena of translational and precision medicine. This program’s affiliation to a basic research institute instead of a medical school gives it a unique position and strength by offering education in basic research, drug discovery and development, preclinical models, and mechanistic insights into diseases. With a strong emphasis on team science and the integration of attending physicians from Scripps Health in all projects, this program will produce leaders with the skills required to conduct transformative translational science. To date, this young program has trained only predoctoral fellows. All 8 who have graduated, publishing 31 papers in the process, have remained in science, and 6 students remain supported by the program. Based on this success, and after thorough analysis of what bottlenecks remain in the delivery of efficient translational research, we will implement a series of changes to enhance our program by carrying out 3 specific aims: Specific Aim 1. Expand the current coursework to deliver cutting-edge clinical-translational research competencies and enhance mentorship. This objective will be achieved by adding new courses aimed at addressing the most current scientific and medical issues. Mentorship will be reinforced by coordinating each project around monthly meetings with presentation of progress. Specific Aim 2. Expand the current TL1 program to provide the full representation of trainees necessary for successful clinical-translational projects. In addition to our successful predoctoral program, we will include a 3-year postdoctoral pathway to add translational competencies beyond PhD completion. Specific Aim 3. Increase diversity in our training program. Precision medicine cannot be achieved without an acute perception of diversity. Our efforts will be targeted at increasing the number of underrepresented students in our program by adding recruitment relationships with colleges and graduate schools serving these populations. These changes and evolution of the program come at a remarkable time with two exciting developments at TSRI: the integration of the California Institute for Biomedical Research (Calibr) a drug-discovery and development institute that will allow training of TL1 students in that field, and the creation of a Scripps Research Biosciences College in 2018.

训练核心（TL1） - 摘要 Scripps转化科学研究所（STSI）TL1培训计划的目的是给予前和 博士后研究员在旨在 使它们在转化和精确医学的复杂领域有效。该计划的会员 基础研究所而不是医学院，通过提供的来使其具有独特的位置和优势 基础研究，药物发现和开发，临床前模型以及机械见解的教育 疾病。强烈着重于团队科学以及从斯克里普斯（Scripps）主治医师的一体化 在所有项目中的健康状况中，该计划将以进行变革性的技能培养领导者 翻译科学。迄今为止，这个年轻的计划仅培训了前专家。所有8个 毕业，在此过程中发表31篇论文，一直存在于科学中，有6名学生仍然受到支持 通过程序。基于这一成功，并在彻底分析了瓶颈在交货中保留的瓶颈 在有效的翻译研究中，我们将通过携带一系列更改来增强我们的计划 超出3个特定目的： 特定目的1。扩展当前的课程以提供尖端的临床翻译研究 能力和增强心态。该目标将通过添加针对的新课程来实现 解决最新的科学和医学问题。指导将通过协调来加强 围绕每月会议进行计划，并展示进度。 特定目标2。扩展当前的TL1计划以提供培训的完整代表 成功的临床翻译项目所必需的。除了我们成功的专业计划之外， 我们将包括一项为期3年的博士后途径，以添加超出博士学位的翻译能力。 特定目标3。增加我们的培训计划的多样性。没有精密药物就无法实现 对多样性的敏锐感知。我们的努力将以增加代表性不足的数量的目标 我们计划中的学生通过与大学和研究生院添加招聘关系，为这些 人群。 这些程序的这些变化和演变在一个了不起的时刻，有两个令人兴奋的发展 TSRI：加利福尼亚生物医学研究所（校准）的整合药物发现和 开发研究所将允许该领域的TL1学生培训，并创建Scripps 研究生物科学院于2018年。