Core I: Biostatistics Core

核心一：生物统计学核心

• 批准号: 10084118
• 负责人: LYNNE R WILKENS
• 金额: $ 17.62万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-28 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10084118
• 关键词: Advisory Committees; Biometry; Biostatistics Core; Biostatistics Shared Resource; Cancer Center; Collaborations; Consultations; Data; Data Analyses; Exposure to; Guam; Incidence; Information Technology; Malignant Neoplasms; Mentors; Methods; Monitor; Pacific Islands; Pilot Projects; Population; Prevalence; Research; Research Design; Research Infrastructure; Research Project Grants; Resource Sharing; Respondent; Risk Factors; Role; Sampling; Scheme; Students; Universities; anticancer research; cancer health disparity; cancer risk; data curation; data management; data resource; experience; faculty mentor; health disparity; health equity; member; novel strategies; outreach; protective factors; sound

PROJECT SUMMARY/ABSTRACT The Biostatistics Shared Resource Core (BSRC) serves a critical role in enhancing the U54 research infrastructure. The BSRC is led by biostatisticians who have the expertise and experience to contribute substantially to successful cancer research in Pacific Island populations. The BSRC adds to the scientific rigor of U54 research through sound statistical advice and inclusion of novel approaches, such as Respondent Driven Sampling and an interim analysis scheme in current projects. The BSRC provides support for all quantitative aspects of research endeavors, including study design, data management, statistical programming, data analysis, and interpretation and presentation of results. A primary biostatistician is assigned to each U54 research project in order to provide consultation throughout the study. The BSRC Leaders serve as non-voting members of the U54 Internal Advisory Committee and provide statistical review of, and input to, new research concepts. The Shared Resource builds capacity for health disparities research at University of Guam and the University of Hawai`i Cancer Center through mentoring of faculty and students on quantitative methods, thus building research capacity, and through formal seminars. Additionally, the BSRC will facilitate research through curation of information on cancer risks and prevalence of cancer risk and protective factors in Guam and Hawai`i to be used to inform research projects and through creation, with the Information Technology Shared Resource, of a platform for storage and sharing of current and past U54 project data and documents.

项目概要/摘要 生物统计学共享资源核心 (BSRC) 在加强 U54 研究方面发挥着关键作用 基础设施。 BSRC 由生物统计学家领导，他们拥有专业知识和经验，可以做出贡献 极大地促进了太平洋岛屿人群癌症研究的成功。 BSRC 增强了科学严谨性 通过合理的统计建议和新方法（例如受访者）的纳入，U54 研究的 当前项目中的驱动采样和中期分析方案。 BSRC 为所有人提供支持 研究工作的定量方面，包括研究设计、数据管理、统计 编程、数据分析以及结果的解释和呈现。指定一名主要生物统计学家 每个 U54 研究项目，以便在整个研究过程中提供咨询。 BSRC领导服务 作为 U54 内部咨询委员会的无投票权成员，并提供统计审查和意见， 新的研究理念。共享资源增强了大学健康差异研究的能力 关岛和夏威夷大学癌症中心通过对教师和学生进行定量指导 方法，从而建设研究能力，并通过正式研讨会。此外，BSRC 将促进 通过整理有关癌症风险以及癌症风险流行率和保护因素的信息来进行研究 关岛和夏威夷将用于为研究项目提供信息，并通过创建信息 技术共享资源，用于存储和共享当前和过去的 U54 项目数据和 文件。