Functional Limitations and Disability Among Middle-Aged Adults

中年成人的功能限制和残疾

基本信息

批准号：
10084231
负责人：
Christopher Barrett Bowling
金额：
$ 59.41万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-01-15 至 2023-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10084231
关键词：
Activities of Daily Living Address Adult Age Age-Years Aging Ancillary Study Blood Pressure Cardiovascular Diseases Caring Chronic Cognitive Coronary Artery Risk Development in Young Adults Study Data Development Diabetes Mellitus Enrollment Equilibrium Event Gait speed Geriatrics Glucose Hand Strength Health Healthcare Individual Information Systems Injury Knowledge Leg Life Living Wills Measurement Measures Medicare Obesity Participant Pathway interactions Patient Outcomes Assessments Patient Self-Report Persons Phenotype Physical Function Physical Performance Physical activity Physiological Population Population Study Prevalence Psychosocial Factor Race Rehabilitation therapy Reporting Risk Factors Role Schedule Socioeconomic Factors Telephone Testing Time Walking Weight Gain Woman aging population body system clinical care cohort cost design disability emerging adult follow-up functional decline functional status human old age (65+)improved instrumental activity of daily living men middle age multiple chronic conditions neglect novel strategies population based population health prevent public health relevance racial difference racial disparity sedentary lifestyle

项目摘要

Project summary/Abstract The burden of functional limitations (restrictions in basic physical actions) and disability (problems with daily activities and life participation) may be more common in middle-aged US adults than previously recognized. However, studies of middle-age populations have not typically included functional assessments. The Coronary Artery Risk Development in Young Adults (CARDIA) study provides a unique opportunity to study functional status in a diverse, aging cohort. The Year 35 in-person exam is scheduled for 2020 and 2021, at which time, participants will be 53 to 65 years old. We propose a CARDIA ancillary study to obtain measures of function by self-report and physical performance to be paired with the existing data collected from early adulthood through middle age to address the following aims: 1. To quantify the burden of functional limitations and disability in middle age and assess the degree to which this can be attributed to the accumulation of chronic conditions, 2. To assess domains of functional limitations and disability captured by physical performance versus self-report, 3. To identify health-related risk factors in early adulthood for functional limitations and disability in middle-age, 4. To identify health-related, socioeconomic, and psychosocial factors that contribute to between- and within- race differences in functional limitations and disability among middle-aged adults. We will add measures of physical performance (fast and usual gait speed, single leg balance, timed chair stands, 6-minute walk test, and grip strength) to the CARDIA Year 35 exam (projected N=3,270; 1,563 black, 1,707 white). Also, self- reported functional limitations (Patient-Reported Outcomes Measurement Information System [PROMIS] Physical Function Short Form 20a) and disability measures (basic and instrumental activities of daily living) will be added to the Year 35 exam and annual telephone calls (1 call prior to and 2 after the Year 35 exam). As studies of younger populations have not often included functional assessments, the conceptualization, measurement approaches, risk factors, and implications of functional limitations and disability are poorly understood. Filling this knowledge gap by adding appropriate functional measures to an ongoing population based cohort, that represents the next wave of aging black and white adults will lead to new approaches to prevent functional decline and improve population health.

项目摘要/摘要功能限制的负担（基本身体动作的限制）和残疾（每天都有问题在美国成年人中，活动和生活参与可能比以前所认识的更为普遍。但是，对中年人群的研究通常不包括功能评估。冠状动脉年轻人的动脉风险发展（CARDIA）研究为研究功能提供了独特的机会处于多元化，衰老的队列中的状态。 35年的面对面考试定于2020年和2021年，当时参与者将年满53至65岁。我们提出了一项Cardia辅助研究，以通过自我报告和身体表现与从成年初期收集的现有数据配对解决以下目标的中年：1。量化功能限制和残疾的负担中年龄并评估这可以归因于慢性条件的积累的程度2。评估由身体绩效与自我报告捕获的功能局限性和残疾领域的领域， 3。在成年初期确定与健康相关的风险因素，以解决中年的功能限制和残疾， 4。确定与健康有关的，社会经济和社会心理因素，有助于之间和内部之间中年成年人功能局限性和残疾的种族差异。我们将添加措施身体表现（快速和通常的步态速度，单腿平衡，定时椅子架，步行6分钟，测试，和抓地力）到CADCIA 35年的考试（预计n = 3,270; 1,563黑色，1,707白色）。另外，自我报告的功能局限性（患者报告的结果测量信息系统[Promis] 身体功能简短表格20a）和残疾措施（日常生活的基本和工具活动）将添加到35年级考试和年度电话（35年后的1个电话和2个电话）中。作为对年轻人群的研究通常不包括功能评估，概念化，测量方法，风险因素以及功能限制和残疾的影响很差理解。通过在正在进行的人群中添加适当的功能措施来填补这一知识差距基于基于的同类，代表下一波衰老的黑白成年人将导致新的方法防止功能下降并改善人口健康。