Post-Graduate Research Training Aligned with the NIMH Strategic Plan

符合 NIMH 战略计划的研究生研究培训

• 批准号: 10115122
• 负责人: JOHN G CSERNANSKY
• 金额: $ 19.69万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-05-10 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10115122
• 关键词: ABCB1 gene; Address; Appointment; Aptitude; Award; Biological Markers; Brain; Cancer Education Grant Program; Career Choice; Clinical; Clinical Research; Collaborations; Data Analyses; Diagnosis; Disease; Education; Education Projects; Educational Curriculum; Ensure; Evaluation; Faculty; Fellowship; Fostering; Funding; Future; Grant; Individual; K-Series Research Career Programs; Knowledge; Link; Master of Science; Medicine; Mental disorders; Mentors; Midwestern United States; Monitor; National Institute of Mental Health; Neurosciences; Neurosciences Research; Patients; Physicians; Preparation; Program Development; Psychiatric therapeutic procedure; Psychiatrist; Psychiatry; Research; Research Design; Research Methodology; Research Support; Research Training; Residencies; Resource Development; Resources; SECTM1 gene; Schools; Scientist; Selection for Treatments; Series; Strategic Planning; Structure; Time; Training; Training Programs; Training Support; Training and Education; Translational Research; United States National Institutes of Health; Universities; Wages; Writing; career; career development; clinical investigation; clinical practice; cohort; education research; effective therapy; expectation; experience; hands on research; improved; interest; medical schools; medical specialties; programs; recruit; skill acquisition; skills; success; translational neuroscience; treatment effect; treatment planning

Project Summary There is a strong need in psychiatry to invigorate the career development of physician-scientists who can apply advances in neuroscience to applications that improve the diagnosis and treatment of psychiatric patients. The need for physician-scientists in psychiatry may be greater than in other fields of medicine, since at present, we still rely almost entirely on the clinical interaction between clinician and patients to obtain the information needed to establish a diagnosis, to select the most appropriate treatment, and to evaluate the effects of that treatment. One day we may be able to apply biomarkers derived from a knowledge of disease mechanisms to assist in establishment of a diagnosis and to select treatment, but even these biomarkers will need to be validated using clinical information collected by physician-scientists, and then integrated with the patient's clinical narrative to arrive at a precise diagnosis and develop an effective treatment plan. The proposed R25 program at Northwestern University Feinberg School of Medicine (NUFSM) aims to enrich research training for general psychiatry residents and clinical fellows during their usual period of training, so that these individuals maintain and further consolidate their commitment to a career in research that is aligned with the strategic plan of NIMH. We aim to support their training so that they strengthen their commitment to an academic career pathway, where they will acquire critical skills in study design, research methodologies, data analysis, grant writing and career development. Applicants to our post-graduate training programs in psychiatry already demonstrate strong interests and aptitudes for academic careers. Thus, our Northwestern trainees are excellent candidates for an enriched research experience. Also, educational assets currently in place at Northwestern through our CTSA, Physician Scientist Training Programs, Masters of Clinical Investigation program, and various interdepartmental graduate programs can be leveraged to increase the impact of the proposed R25 program. If successful, this application would create the only R25 physician-scientist training program for psychiatry residents in the central Midwest.

项目摘要 精神病学有很大的需求激发可以申请的医师科学家的职业发展 神经科学对改善精神病患者诊断和治疗的应用的进展。这 在精神病学领域的医师科学家的需求可能比其他医学领域都要大，因为目前，我们 仍然几乎完全依靠临床医生和患者之间的临床相互作用来获取信息 需要建立诊断，选择最合适的治疗方法并评估其影响 治疗。有一天，我们可能能够将源自疾病机制知识的生物标志物应用于 协助建立诊断并选择治疗，但即使是这些生物标志物也需要 使用医师科学家收集的临床信息进行验证，然后与患者的临床信息进行了验证 临床叙述以进行精确的诊断并制定有效的治疗计划。 西北大学Feinberg医学院（NUFSM）拟议的R25计划旨在丰富 在通常的培训期间，对普通精神病学居民和临床研究员进行研究培训，因此 这些人维持并进一步巩固了他们对研究职业的承诺 与NIMH的战略计划。我们旨在支持他们的培训，以便他们加强他们对 学术职业途径，他们将获得研究设计，研究方法，数据的关键技能 分析，赠款写作和职业发展。我们的精神病学研究生培训计划的申请人 已经表现出对学术职业的强烈利益和能力。因此，我们的西北学员是 获得丰富研究经验的优秀候选人。此外，目前有教育资产 西北航空通过我们的CTSA，医师科学家培训计划，临床调查硕士 可以利用计划和各种部门间的研究生课程来增加 拟议的R25程序。如果成功，此应用程序将创建唯一的R25医师科学家培训 中西部中部精神病学居民计划。