Validation and Expansion of Established Norms for Measures of Tinnitus Perception

耳鸣感知测量既定规范的验证和扩展

• 批准号: 10112759
• 负责人: JAMES A HENRY
• 金额: --
• 依托单位: PORTLAND VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10112759
• 关键词: Acoustics; Address; Age; Audiology; Categories; Characteristics; Chronic; Clinic; Clinical; Clinical Research; Code; Computers; Custom; Data; Data Analyses; Data Collection; Data Set; Databases; Development; Devices; Ear; Effectiveness; Enrollment; Equipment; Evaluation; Financial compensation; Foundations; Frequencies; Funding; Guidelines; Hearing; Individual; Intervention; Knowledge; Literature; Loudness; Masks; Measurement; Measures; Medical; Methodology; Methods; Participant; Patients; Perception; Performance; Persons; Pitch Perception; Prevalence; Property; Protocols documentation; Psychoacoustics; Psychophysics; Publishing; Questionnaires; Reaction; Reference Standards; Reference Values; Reporting; Reproducibility; Research; Research Personnel; Resources; Services; Sleep disturbances; Stimulus; System; Tablets; Techniques; Testing; Time; Tinnitus; Training; Training Programs; Treatment Protocols; Update; Validation; Veterans; Work; age group; base; clinical application; cohort; design; disability; effective therapy; emotional distress; improved; inclusion criteria; indexing; programs; sound; treatment effect

Our previous work has collected normative data for measures of both tinnitus perception and tinnitus functional effects (reactions). Participants with chronic tinnitus, who were not receiving tinnitus-specific intervention, completed tinnitus psychoacoustic measures and tinnitus questionnaires at 0, 1, 3, and 6 months. Participants were included in each of six age ranges (18-30; 31-40; 41-50; 51-60; 61-70; 70+). These data will contribute to age-specific reference values for the different measures once all data analyses are complete (final participant testing occurred on October 30, 2018). The proposed study will extend and expand this effort by: (1) building on the normative standards database by testing a cohort of new participants; (2) assessing long-term repeatability of tinnitus psychoacoustic measures by obtaining additional longitudinal data from participants recalled from the previous study; (3) developing methodology to evaluate individual pitch-perception ability and providing training as needed; (4) evaluating the effect of pitch training on ability to match tinnitus pitch with greater precision; and (5) continuing development of the tablet-based tinnitus evaluation system (TES) for clinical utility by improving the interface and other performance features, and by creating a rapid assessment program to obtain reliable loudness matches and pitch matches in under 10 minutes. To accomplish these objectives, new participants will be enrolled into two separate cohorts of 150 and 100 individuals (total new enrollment n=250). Both cohorts of new participants will meet the same inclusion criteria as used in the previous study. The 150 new participants will undergo repeated testing at baseline and at 1, 3, and 6 months to replicate testing as done during the previous study. The separate cohort of 100 new participants will be enrolled to evaluate a training program for pitch matching. Of these, half will complete a program of pitch- perception testing and training that will be administered prior to the start of baseline testing (comparison of pitch matching data between groups with vs. without training will determine if the program improves within- session reliability of the pitch matching test). Finally, a third cohort of 100 of the previous study's participants will return to repeat testing ~3 years following their baseline testing to obtain long-term reliability data. In addition to data collection, efforts will be ongoing to complete development and validation of the tablet-based TES with the intent to ready this system for clinical application. A test protocol requiring 5-10 minutes is needed for the TES to have the potential to achieve more widespread use among VA audiologists. A rapid TES protocol will be developed, tested, and validated with a subset of participants to achieve this objective. Completing the work described in this application will accomplish many objectives, including making tinnitus psychoacoustic measures more useful and practical for clinical and research utilization.

我们以前的工作已经收集了用于衡量耳鸣和耳鸣功能的标准数据 效果（反应）。没有接受耳鸣的慢性耳鸣的参与者， 在0、1、3和6个月完成了耳鸣的心理声音措施和耳鸣调查表。参与者 包括在六个年龄范围（18-30; 31-40; 41-50; 51-60; 61-70; 70+）中的每个年龄范围中。这些数据将有助于 一旦完成所有数据分析，不同度量的年龄特异性参考值（最终参与者 测试发生在2018年10月30日）。拟议的研究将通过以下方式扩展和扩展这项工作：（1）建造 在规范标准数据库中测试新参与者的队列； （2）长期评估 通过从参与者那里获得额外的纵向数据，耳鸣的心理声音措施的可重复性 从先前的研究中召回； （3）开发方法来评估个体的音高感知能力和 根据需要提供培训； （4）评估音高训练对与耳鸣音调匹配能力的影响 更高的精度； （5）持续开发基于平板电脑的耳鸣评估系统（TES） 通过改善界面和其他性能功能，并创建快速评估，通过临床实用程序 计划在不到10分钟内获得可靠的响度匹配和音高匹配。完成这些 目标，新参与者将被招募成两个单独的人群，分别为150和100个人（总计 注册n = 250）。两个新参与者的队列都将符合与 先前的研究。 150名新参与者将在基线和1、3和6个月进行重复测试 在上一项研究中进行的复制测试。由100名新参与者组成的单独队列将 注册以评估用于音高匹配的培训计划。其中，一半将完成一个音调程序 - 在基线测试开始之前将进行的感知测试和培训（比较 与未经培训的组之间的俯仰匹配数据将确定该计划是否在内部改善 音高匹配测试的会话可靠性）。最后，先前研究的100个参与者中的第三个队列 将在基线测试后3年返回重复测试，以获取长期可靠性数据。在 除了数据收集外，还将努力完成基于平板电脑的开发和验证 意图准备该系统进行临床应用。需要5-10分钟的测试协议是 TES有可能在VA听力学家中获得更广泛的使用。快速 协议将通过一部分参与者制定，测试和验证，以实现这一目标。 完成本应用程序中描述的工作将实现许多目标，包括制作耳鸣 心理声学措施对临床和研究利用更有用，更实用。