FASEB's "The Translational Neuroimmunology Conference: From Mechanisms to Therapeutics."

FASEB 的“转化神经免疫学会议：从机制到治疗学”。

• 批准号: 10065269
• 负责人: Thomas E Lane
• 金额: $ 0.3万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10065269
• 关键词: Alzheimer' s Disease; Area; Basic Science; Behavior; CNS autoimmune disease; Central Nervous System Diseases; Central Nervous System Infections; Clinical; Collaborations; Communication; Communities; Complex; Development; Disease; Disease Progression; Educational workshop; Ensure; Environment; Equilibrium; Ethnic Origin; Evaluation; Fostering; Funding; Genetic; Glioblastoma; Goals; Grant; Health; Health system; Homeostasis; Human; Immune response; Immune system; Immunologist; Immunology; Individual; Innate Immune Response; Knowledge; Life; Maintenance; Meninges; Microbiology; Molecular; Multiple Sclerosis; Nerve Degeneration; Nervous System Physiology; Nervous system structure; Neuraxis; Neurodegenerative Disorders; Neurodevelopmental Disorder; Neuroimmune; Neuroimmunomodulation; Neurology; Neurosciences; Oral; Participant; Pathogenicity; Pathology; Pathway interactions; Postdoctoral Fellow; Preparation; Publications; Regulation; Research; Research Personnel; Role; STEM field; Science; Scientist; Sex Chromosomes; Spinal cord injury; Students; Surveys; Talents; Therapeutic; Time; Tissues; Translating; Translational Research; Work; adaptive immune response; base; career; combat; defined contribution; improved; meetings; member; microbial; multidisciplinary; nervous system disorder; neuroimmunology; neuroinflammation; neurological pathology; next generation; pathogen; pathogenic microbe; posters; prevent; programs; recruit; repaired; response; success; supportive environment; symposium; targeted treatment; therapy development; toxicant

Abstract (30 lines max): The purpose of this R13 submission is to request funds for trainees and for a limited number of junior investigator speakers and those from groups traditionally underrepresented in the STEM fields to participate in the 2020 FASEB Science Research Conference: The Translational Neuroimmunology Conference: from mechanisms to therapeutics. This will be the 15th FASEB Neuroimmunology conference and will be held at the Babson Executive Conference Center from July 19-23, 2020. The last FASEB meeting was held in Snowmass, CO in 2018, where Dr. Benjamin Segal was elected as co-chair to work with Dr. Thomas Lane who was the 2018 co-chair and is the 2020 chair. The 2020 conference builds upon the excellence of previous meetings and brings together a diverse group of neuroscientists, immunologists, clinicians, microbiologists, translational and basic research scientists at a venue and with a program fostering interaction between individuals with different expertise and at different career stages. Previous evaluations have ranked this conference highly for outstanding presentations and discussion time, for high impact speakers who remain for the duration of the conference, selection of abstracts from junior scientists and graduate trainees for short platform presentations, well-attended poster sessions, time for free and open discussions between speakers and attendees aimed at fostering new and ongoing collaborations. The 2020 program is aimed at defining the contributions of neuroimmune interactions in CNS as it relates to emerging topics including understanding the role of sex chromosomes and neuroinflammation and assessing the role of the innate immune response in neurodegeneration. We also seek to explore the opportunities and challenges for harnessing neuroimmune interactions as therapies for classic neurologic and neurodegenerative diseases including multiple sclerosis, Alzheimer’s disease, spinal cord injury, glioblastoma and CNS autoimmune diseases. In response to evaluation requests from trainees and junior investigators attending the 2018 conference, new this year are addition of two workshops discussing pragmatic issues and careers aimed at bridging pathways from discovery to human therapies and the role of scientific rigor in grant preparation and publication. In aggregate, the specific goals of this conference are to: 1) provide a forum for the presentation of unpublished, cutting-edge research by investigators from diverse fields applicable to neuroimmune regulation of CNS health and disease; 2) provide forums for both formal and informal discussions on how results from complementary fields advance our understanding of how neuroimmune interactions support CNS function and health lifelong and can be modified by genetics, pathogens, toxicants and behavior to drive disease pathology, and 3) ensure development and integration of young investigators from diverse backgrounds and those traditionally under- represented in these fields into the broader research community in a meaningful and interactive way. Altogether, attendees will enjoy a multidisciplinary group of researchers not found together at other specialized conferences and will benefit from the focus on the opportunities & challenges in translating research discoveries to therapies.

摘要（最大30行）： 此R13提交的目的是要求培训和有限数量的初级资金 调查员的发言人和来自STEM领域中人数不足的团体的演讲者参加 2020年Faseb科学研究会议：转化神经免疫学会议：摘自 理论的机制。这将是第15届FASEB神经免疫学会议，将在 Babson执行会议中心于2020年7月19日至23日。上一次FASEB会议在Snowmass举行 CO在2018年，本杰明·塞加尔（Benjamin Segal）博士当选为联合主席，与托马斯·莱恩（Thomas Lane）博士合作。 2018年联席主席，是2020年的主席。 2020年会议以先前会议的卓越为基础 并汇集了一群神经科学家，免疫学家，临床医生，微生物学家，翻译 以及一个场地的基础研究科学家，并通过计划促进了 不同的专业知识和不同的职业阶段。以前的评估对这次会议的排名很高 出色的演讲和讨论时间，适用于在此期间保持的高影响力的演讲者 会议，从初级科学家和研究生培训人员中选择简短平台演示文稿的摘要， 受人尊敬的海报会议，演讲者和与会者之间的免费和公开讨论的时间 促进新的和正在进行的合作。 2020年计划旨在定义 中枢神经系统中的神经免疫性相互作用与新兴主题有关，包括了解性别的作用 染色体和神经炎症和评估先天免疫反应在 神经变性。我们还寻求探索利用神经免疫的机会和挑战 相互作用作为经典神经和神经退行性疾病的疗法，包括多发性硬化症， 阿尔茨海默氏病，脊髓损伤，胶质母细胞瘤和CNS自身免疫性疾病。响应 受训人员和初级调查员的评估请求参加了2018年会议，今年的新要求是 增加了两个研讨会，讨论了旨在从发现中桥接途径的务实问题和职业 人类疗法以及科学严谨在赠款准备和出版中的作用。总体上， 本次会议的具体目标是：1）提供一个论坛，以展示未出版的尖端 来自CNS健康和疾病神经免疫调节的潜水领域的研究人员的研究； 2）提供有关正式和非正式讨论的论坛，就完成领域的结果如何发展提供 我们对神经免疫相互作用如何支持CNS功能和健康终生的理解，可以是 通过遗传学，病原体，有毒物质和行为来修饰疾病病理学，3）确保 来自潜水员背景的年轻研究者以及传统上不足的研究者的发展和整合 在这些领域以有意义和互动的方式代表了更广泛的研究社区。 总而言之，与会者将享受一个在其他专业的跨学科研究人员群体 会议，将受益于翻译研究的机遇和挑战的关注 疗法的发现。