Development of a Novel Personalized Risk Assessment for College Alcohol Prevention

开发一种新颖的个性化大学酒精预防风险评估

• 批准号: 10013117
• 负责人: DANIELLE M DICK
• 金额: $ 20.34万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-10 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10013117
• 关键词: Address; Administrator; Adopted; Alcohol consumption; Alcohol or Other Drugs use; Behavioral; Control Groups; Data; Development; Drug usage; Effectiveness; Emotional; Etiology; Feedback; Focus Groups; Foundations; Frequencies; Goals; Health; Health Benefit; Human Resources; Individual; Infrastructure; Injury; Institutes; Intervention; Knowledge; Lead; Legal; Life Cycle Stages; Measures; Mental Health; Pathway interactions; Phase; Physiological; Policies; Population; Positioning Attribute; Postdoctoral Fellow; Preventive Intervention; Procedures; Recommendation; Reporting; Research; Research Personnel; Research Project Grants; Resources; Risk; Risk Assessment; Risk Factors; Science; Students; Surveys; Testing; Time; Translating; Treatment Efficacy; Universities; Work; adverse outcome; alcohol and other drug; alcohol misuse; alcohol prevention; assault; base; binge drinking; brief motivational intervention; college; college drinking; cost; evidence base; illicit drug use; innovation; intervention program; novel; personalized medicine; prevent; randomized controlled design; service providers; sexual encounter; substance use prevention; tool; university student; Address; Administrator; Adopted; Alcohol consumption; Alcohol or Other Drugs use; Behavioral; Control Groups; Data; Development; Drug usage; Effectiveness; Emotional; Etiology; Feedback; Focus Groups; Foundations; Frequencies; Goals; Health; Health Benefit; Human Resources; Individual; Infrastructure; Injury; Institutes; Intervention; Knowledge; Lead; Legal; Life Cycle Stages; Measures; Mental Health; Pathway interactions; Phase; Physiological; Policies; Population; Positioning Attribute; Postdoctoral Fellow; Preventive Intervention; Procedures; Recommendation; Reporting; Research; Research Personnel; Research Project Grants; Resources; Risk; Risk Assessment; Risk Factors; Science; Students; Surveys; Testing; Time; Translating; Treatment Efficacy; Universities; Work; adverse outcome; alcohol and other drug; alcohol misuse; alcohol prevention; assault; base; binge drinking; brief motivational intervention; college; college drinking; cost; evidence base; illicit drug use; innovation; intervention program; novel; personalized medicine; prevent; randomized controlled design; service providers; sexual encounter; substance use prevention; tool; university student

PROJECT SUMMARY The primary goal of this R34 proposal is to conduct pilot testing of a new intervention for college student substance use. Risky substance use among college students is widespread, and associated with numerous adverse consequences. Although brief motivational interventions (BMIs) have been widely adopted by colleges to address risky alcohol use, most studies find only small to moderate effects, with a review of college student drinking interventions noting that “significant enhancement of personalized feedback intervention efficacy has not been observed in over 15 years of study” (Miller et al. 2015). Current interventions focus on students’ current substance use, and largely do not address underlying risk factors and the pathways that lead students to use. There is compelling evidence that students use/misuse alcohol for different reasons, and that externalizing, internalizing, and physiological factors strongly predict college students’ substance use and problems. The fast-growing field of personalized medicine is harnessing our growing knowledge about underlying etiological factors to provide individuals with specific information about their unique risk profiles and personalized recommendations, in order to motivate and enable individuals to better self-regulate their health. With this R34 we will evaluate an on-line Personalized Risk Assessment (PRA) for college students that provides feedback about the individual’s specific core underlying risk factors for substance use, and how these factors can lead to substance problems, along with personalized recommendations and resources. The project will capitalize on foundational work from our unique, on-going university-wide research project (Spit for Science; S4S), in which >12,000 students (~70% of five years of incoming freshmen thus far) are being followed longitudinally with surveys assessing substance use and related factors across the college years. From these data we have identified risk factors most strongly related to college students’ substance use, and have developed an associated research center that brings together S4S researchers with university administrators and student affairs personnel to translate this research into enhanced university programming and policy. Making use of this extant collaborative network, we will (Aim 1) finalize the editing and programming of our on- line personalized risk assessment platform; (Aim 2) systematically refine the risk questions and feedback tools by conducting four focus groups (N= 40) and an open trial (N=40) with college students with varying risk profiles, and one focus group with college wellness staff and service providers; and (Aim 3) preliminarily evaluate the efficacy of the PRA in comparison to an assessment only control group, a standard BMI, and a PRA+BMI condition to test whether there are additive or interactive effects, using a randomized controlled design of N = 300 freshman with measures of substance use and academic functioning collected at 3 time points across the freshman year. College represents a unique opportunity to intervene and have positive life- course altering health benefits for a significant, and increasingly diverse portion of the population.

项目摘要 该R34提案的主要目标是对大学生进行新干预的试点测试 使用物质。大学生中使用风险的药物是普遍的，并且与许多 不利后果。尽管大学广泛采用了简短的动机干预措施（BMI） 为了解决风险的饮酒，大多数研究仅发现小到中度的影响，并对大学生进行了审查 饮酒干预措施指出，“个性化反馈干预效率的显着提高已有 在超过15年的研究中没有观察到”（Miller等，2015）。目前的干预措施关注学生 当前的物质使用，并且在很大程度上无法解决潜在的风险因素和导致学生的途径 使用。有令人信服的证据表明，学生出于不同的原因使用/MISSUSE酒精，并且 外在化，内在化和身体因素强烈预测大学生的物质使用和 问题。个性化医学的快速发展领域正在利用我们对 基本的病因因素为个人提供有关其独特风险概况的特定信息和 个性化建议，以激励并使个人更好地自我调节自己的健康。 使用此R34，我们将为大学生评估一项在线个性化风险评估（PRA） 提供有关个人特定核心使用物质使用风险因素的反馈，以及如何 因素可能导致主题问题，以及个性化的建议和资源。项目 将从我们独特的，正在进行的大学范围内的研究项目（Spit for Science for Science）中利用基础工作； S4S），其中> 12,000名学生（迄今为止五年新生的70％）正在遵循 在整个大学期间评估药物使用和相关因素的调查纵向。从这些 我们已经确定了与大学生使用物质最密切相关的风险因素，并且 开发了一个相关的研究中心，该中心将S4S研究人员与大学管理员汇集在一起 和学生事务人员将这项研究转化为增强的大学编程和政策。 利用这个广泛的协作网络，我们（目标1）最终确定了我们的运行的编辑和编程 线个性化的风险评估平台； （目标2）系统地完善风险问题和反馈工具 通过与具有不同风险的大学生进行四个焦点小组（n = 40）和一个公开试验（n = 40） 个人资料，以及一个与大学健康人员和服务提供者的焦点小组； （目标3）初步 与仅评估对照组，标准BMI和A相比，评估PRA的效率 使用随机控制 N = 300大一新生的设计，并在3次收集的物质使用和学术功能的测量 大一年度的积分。大学代表了干预和拥有积极生活的独特机会 - 在大量且越来越多样化的人群中改变健康益处的课程。