Development of a Telehealth Screener and Assessment for Infants at-risk for ASD in Diverse Communities.

为不同社区中有自闭症谱系障碍风险的婴儿开发远程医疗筛查和评估。

• 批准号: 10024067
• 负责人: Meagan Ruth Talbott
• 金额: $ 19.63万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-30 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10024067
• 关键词: Address; Age; Age-Months; Behavioral; Benchmarking; Biological Markers; Caregivers; Collection; Communication; Communities; Country; Data; Development; Diagnostic; Discipline; Early identification; Eligibility Determination; Ensure; Evaluation; Family; Feasibility Studies; Feedback; Funding; Future; Geography; Goals; Growth; Health Services Accessibility; Home environment; Infant; Infant Behavior; Infant Development; Intervention; Intervention Trial; Life; Measures; Mediating; Methods; Modeling; Monitor; Neurobiology; Outcome; Parents; Phase; Protocols documentation; Publications; Randomized; Reporting; Research Personnel; Resources; Risk; Rural; Sampling; Scientist; Screening procedure; Services; Siblings; Symptoms; System; Testing; Training; Travel; Universities; Validity and Reliability; Visit; Vulnerable Populations; Wait Time; Waiting Lists; aged; autism spectrum disorder; autistic children; base; community based participatory research; community setting; control trial; cost; cost effective; disorder risk; field study; high risk infant; high risk population; improved; longitudinal analysis; meetings; prospective; recruit; routine screening; satisfaction; screening; social communication; standardize measure; telehealth

Project Summary The overall goal of this proposal is to develop a telehealth procedure for screening infants 6-12 months of age for early autism spectrum disorder (ASD) symptoms. While some promising biomarkers have been identified for infants in this age range, neurobiological methods are not feasible for widespread implementation, especially in rural and low-resource service systems. Families with early concerns are faced with long waitlists for an evaluation and often must travel long distances for evaluations at centers with appropriate expertise. Telehealth has been used as a cost-effective approach for increasing access to services across many disciplines, and there is some initial use of telehealth treatment approaches in ASD, but there are currently no established telehealth screening procedures to screen infants for ASD. Developing a telehealth screening protocol would provide families an opportunity to access highly trained clinicians and researchers with specialized expertise for initial screening before undertaking the cost and effort required to travel to a center. The first six months of funding will be used to develop, refine, and pilot test this parent-administered protocol in a sample of diverse infants 6-12 months (Aim 1). Feedback from parents and experts will inform final adaptations. The resulting protocol will subsequently be tested via telehealth in a pilot feasibility phase (Aim 2). 30 infants 6-12 months with early ASD symptoms and their caregivers will be recruited nationally, and will complete the telehealth screener quarterly for one year. We will examine the reliability of telehealth-derived measures of infant behavior across consecutive administrations, and compare these measures to existing parent-report measures to assess their validity. Acceptability to parents and feasibility of this telehealth approach to screening will also be evaluated. The overall goal of this project is to develop a protocol for systematically screening, assessing, and monitoring symptomatic infants from a distance. Doing so will increase families' access to specialized evaluations and decrease the significant waiting time between parents' first concerns and infants' first evaluation. It will also lay the groundwork for future efforts to conduct screening and intervention trials and will ultimately help to increase access to high-quality interventions and improve the developmental outcomes of many more underserved children with ASD.

项目摘要 该提案的总体目标是制定远程医疗程序以筛查婴儿6-12 早期自闭症谱系障碍（ASD）症状的月大月。虽然有些有前途 已经确定了该年龄范围内婴儿的生物标志物，神经生物学方法不是 对于广泛的实施，特别是在农村和低资源服务系统中可行的。 早期关注的家庭面临着长期的候补名单进行评估，通常必须旅行 在具有适当专业知识的中心进行评估的长距离。远程医疗已被使用 作为提高许多学科的服务访问访问的一种经济有效的方法， ASD中有一些初步使用远程医疗治疗方法，但目前没有 为ASD筛查婴儿的远程医疗筛查程序。开发远程医疗 筛查协议将为家庭提供机会，以便访问受过训练的临床医生和 具有专业知识的研究人员进行初步筛查，然后进行成本和精力 需要前往中心。前六个月的资金将用于开发，完善，并且 试点在6-12个月的不同婴儿样本中测试该父母管理方案（AIM 1）。 父母和专家的反馈将为最终改编提供信息。结果协议将 随后，在试点可行性阶段通过远程医疗进行测试（AIM 2）。 30个婴儿6-12个月 随着早期的ASD症状及其护理人员将在全国范围内招募，并将完成 远程医疗筛选器季刊一年。我们将研究远程医疗的可靠性 连续行政管理的婴儿行为措施，并比较这些措施 对现有的父母报告措施评估其有效性。对父母的可接受性和可行性 还将评估这种远程医疗筛查方法。这个项目的总体目标是 制定用于系统筛查，评估和监测有症状的协议 远处的婴儿。这样做将增加家庭获得专业评估的访问权限和 减少父母第一次关注与婴儿之间的大量等待时间 评估。它还将为将来的努力奠定基础，以进行筛查和干预 试验，最终将有助于增加获得高质量干预措施并改善 ASD患有更多服务不足的儿童的发展结果。