Career Enhancement Core

职业提升核心

• 批准号: 10001435
• 负责人: MICHAEL J MUGAVERO
• 金额: $ 6.41万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10001435
• 关键词: Academy; Active Learning; Center for Translational Science Activities; Clinical Competence; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Communicable Diseases; Communication; Communities; Competence; Complement; Congenital herpes simplex; Contracts; Critiques; Development; Disease; Educational Activities; Eligibility Determination; Ensure; Enterovirus; Ethics; Faculty; Fostering; Foundations; Funding; Goals; Grant; Growth; Individual; Industry; Information Dissemination; Institution; Investigation; Journals; Knowledge; Leadership; Medicine; Mentors; Methodology; Neonatal; Parechovirus; Patients; Pediatric cohort; Peer Review; Perinatal Infection; Publications; Publishing; Rare Diseases; Research; Research Activity; Research Design; Research Methodology; Research Personnel; Research Project Grants; Research Training; Science; Sepsis; Simplexvirus; Training; Training Programs; Translational Research; Virus Diseases; Writing; base; career; career development; clinical center; cohort; congenital cytomegalovirus; congenital infection; experience; externship; innovation; meetings; next generation; pharmacometrics; professor; programs; recruit; research and development; sabbatical; skills; success; training opportunity; translational scientist

The Congenital and Perinatal Infections Consortium (CPIC) Career Enhancement Core will impact the research career development of the next generation of rare diseases researchers focusing on congenital cytomegalovirus (CMV) disease, neonatal herpes simplex virus (HSV) infection, and neonatal enterovirus (EV) and parechovirus (HPeV) sepsis. The Career Enhancement Core will promote the development of research skills and knowledge for those at all career stages in support of a diverse, innovative, and ethically rigorous research base. The overall goal of the Core is to provide didactic and experiential training in clinical and translational research in order to enhance scientific knowledge and an understanding of stakeholder perspectives unique to the rare diseases patient cohort. To develop CPIC Research Scholars, the Career Enhancement Core will: 1) identify and recruit a promising and diverse cohort of pediatric investigators for career enhancement and mentored research in rare diseases caused by congenital and perinatal infections; 2) expand the formal training of nascent investigators in research methodology, rigorous study design and scientific writing, all skills that are crucial to successful investigation and dissemination of findings in collaboration with UAB's NCATS-funded Center for Clinical and Translational Science (CCTS); and 3) stimulate experiential learning via the development of externships or “mini-sabbaticals” within the CPIC, including industry and community stakeholder partners. Externships across the CPIC will expand and foster increased collaborations and interactions between consortium institutions in a way that contributes to outstanding science and further growth of our research base. Led by Michael J. Mugavero, MD, MHSc, the Career Enhancement Oversight Committee will select fellows and early stage investigators as Research Scholars. These Scholars will receive training in a variety of skills including: 1) the regulatory and ethical requirements of research; special topics specific to rare diseases and CPIC-specific research such as pharmacometrics, 2) an understanding of stakeholder perspective and the communication of scientific results in appropriate formats for different audiences, and methodological issues related to study design and implementation; 3) core competencies of clinical and translational science, including clinical trials considerations as well as grant writing and dissemination of results; and 4) skills needed to review and critique published rare diseases research. In addition to this foundational training, Research Scholars will also receive experiential, mentored research training by Program Faculty.

先天和围产期感染财团（CPIC）职业增强核心将影响 下一代稀有疾病的研究职业发展研究人员专注于先天性 巨细胞病毒（CMV）疾病，新生儿疱疹病毒（HSV）感染和新生儿肠病毒（EV） 和降落伞（HPEV）败血症。职业增强核心将促进研究的发展 各个职业阶段的人的技能和知识，以支持潜水员，创新和道德上的严格 研究基础。核心的总体目标是提供临床和专家培训 转化研究以增强科学知识和对利益相关者的理解 罕见疾病患者队列独有的观点。 为了发展CPIC研究学者，职业增强核心将：1）确定并招募诺言 和潜水员的小儿研究人员的职业增强和改善稀有疾病研究的研究 由先天性和围产期感染引起； 2）扩大对新生调查人员的正式培训 研究方法，严格的研究设计和科学写作，所有对成功至关重要的技能 与UAB NCATS资助的临床中心合作调查和传播调查结果 翻译科学（CCT）； 3）通过开发实质性或 CPIC中的“迷你邮编”，包括行业和社区利益相关者合作伙伴。跨境 CPIC将扩大并促进联盟机构之间的合作和互动 有助于杰出的科学和我们的研究基础的进一步发展的方式。 由MHSC医学博士Michael J. Mugavero领导，职业增强监督委员会将选择研究员 和早期研究人员作为研究学者。这些学者将接受各种技能的培训 包括：1）研究的监管和道德要求；特定于稀有疾病的特殊主题和 CPIC特异性研究，例如药物计量学，2）对利益相关者的观点的理解和 以适当格式的不同受众和方法论问题进行科学结果的交流 与研究设计和实施有关； 3）临床和转化科学的核心能力， 包括临床试验的注意事项以及赠款写作和结果传播； 4）需要的技能 审查和Bealterque发表了稀有疾病研究。除了这种基础培训，研究 学者还将接受课程教职员工的专家研究培训。