Clinical Research Pilot Project Program

临床研究试点项目计划

• 批准号: 10019408
• 负责人: NICOLA LONGO
• 金额: $ 9.51万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-16 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10019408
• 关键词: Biological Assay; Biological Markers; Biopterin; Clinical; Clinical Research; Clinical Trials; Cognitive; Data; Defect; Development; Diagnosis; Disease; Emotional; Evaluation; Funding; Grant; Hyperphenylalaninaemias; Laboratories; Lead; Longitudinal Studies; Morbidity - disease rate; Natural History; Outcome; Performance; Pilot Projects; Prevention; Protocols documentation; Rare Diseases; Registries; Testing; Therapeutic Intervention; data mining; innovation; instrument; novel; novel marker; programs; skills

6. PROJECT SUMMARY – PILOT CORE The Pilot Core will provide funding to studies of innovative ideas or hypotheses that, if successful, will lead to improvements in the understanding, prevention, diagnosis, or treatment of hyperphenylalaninemia, biopterin defects, and related disorders. The core will fund the development of novel laboratory assays or instruments, assessment of novel biomarkers, execution of pilot clinical trials, or performance of pilot data mining studies on data accumulated from the longitudinal natural history study.

6。项目摘要 - 飞行员核心 飞行员核心将为研究创新思想或假设提供资金，如果成功， 改善过度苯丙氨酸血症的理解，预防，诊断或治疗 缺陷和相关疾病。核心将资助新型实验室测定或工具的发展， 评估新型生物标志物，试验临床试验的执行或试点数据挖掘的性能 从纵向自然史研究中积累的数据。