Developmental Research Program

发展研究计划

• 批准号: 10016100
• 负责人: Marc Ladanyi
• 金额: $ 7.42万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10016100
• 关键词: Address; Advisory Committees; Animals; Award; Biology; Budgets; Cancer Etiology; Cause of Death; Clinical; Complement; Development; Diagnosis; Funding; Future; Generations; Goals; Growth; Human; Intervention; Investigator-Initiated Research; Knowledge; Lead; Leadership; Learning; Memorial Sloan-Kettering Cancer Center; Natural History; Pathogenesis; Patients; Philanthropic Fund; Process; Research; Research Personnel; Research Project Grants; Resources; Seeds; Soft tissue sarcoma; Talents; Testing; Translational Research; improved; innovation; outcome forecast; preference; programs; recruit; sarcoma

Developmental Research Program ABSTRACT/DESCRIPTION The purpose of the Developmental Research Program of the MSKCC SPORE in Soft Tissue Sarcoma is to support innovative translational research projects in sarcoma. The translational research projects in this program aim to use knowledge of animal and human sarcoma biology to develop and test interventions related to improving diagnosis, prognosis, and treatment of patients with soft tissue sarcoma. This program will allow us to respond quickly to new opportunities in translational research and will help us recruit new scientific talent into our SPORE and, more broadly, into sarcoma-relevant research. The specific aims of the Developmental Research Program are: 1) to provide seed funding for innovative, investigator- initiated research in the biology, pathogenesis, progression, and natural history of sarcoma, 2) to fund research with exceptional potential to advance the translational research goals of the SPORE. We are budgeting $400,000 yearly for this program including $50,000 from the SPORE award itself and $350,000 in MSKCC institutional and philanthropic funds. The priority for funding will be those initiatives considered most creative and of the highest scientific quality. Preference will be given to projects that complement the long-term research goals of the SPORE and advance our translational research objectives. The executive committee can also solicit and fund experimental or clinical initiatives that address an urgent and specific need in the MSKCC SPORE in Soft Tissue Sarcoma program or a unique research opportunity. The internal scientific advisory committee will review applications to determine priorities for use of these funds and will annually select projects for funding. Projects may apply for a second year of funding through the same competitive process, and the projects that appear most promising will be considered for incorporation into the SPORE as Research Projects, either in current or future funding cycles.

发展研究计划 摘要/描述 软组织中MSKCC孢子的发展研究计划的目的 肉瘤旨在支持肉瘤的创新转化研究项目。翻译 该计划中的研究项目旨在利用动物和人类肉瘤生物学知识 开发和测试与改善诊断，预后和治疗有关的干预措施 软组织肉瘤的患者。该程序将使我们能够快速回应新的 转化研究的机会，并将帮助我们招募新的科学人才 孢子，更广泛地进入与肉瘤相关的研究。特定目标 发展研究计划是：1）为创新，研究人员提供种子资金 - 肉瘤的生物学，发病机理，进展和自然史的研究开始，2） 资助具有非凡潜力的研究，以促进转化研究目标 孢子。我们每年为该计划预算40万美元，包括孢子的$ 50,000 奖励自己，MSKCC机构和慈善基金35万美元。优先级 资金将是那些被认为是最具创造力和最高科学质量的举措。 优先考虑补充孢子的长期研究目标的项目 并促进我们的翻译研究目标。执行委员会还可以征求 资金实验或临床计划，以满足MSKCC的紧急和特定需求 软组织肉瘤计划中的孢子或独特的研究机会。内部科学 咨询委员会将审查申请，以确定使用这些资金的优先事项 每年将选择资金项目。项目可能申请第二年的资金 通过相同的竞争过程，似乎最有前途的项目将是 在当前或将来都被认为将孢子纳入孢子作为研究项目 资金周期。