2022 Bacterial Cell Surfaces GRC/GRS

2022 细菌细胞表面GRC/GRS

基本信息

批准号：
10374358
负责人：
Michael Stephen Trent
金额：
$ 0.5万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-06-14 至 2023-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10374358
关键词：
Animals Anti-Bacterial Agents Area Atmosphere Award Bacteria Bacterial Drug Resistance Bacterial Physiology Basic Science Benign Biochemistry Biological Models Biological Process Biology Biophysics Career Choice Cell division Cell surface Cells Cellular biology Climate Columbidae Communities Development Disease Ensure Experimental Models Feedback Fertilization Fostering Generations Genetic Health Hour Human Image Knowledge Medical Mental Health Microbe Mission Modeling Molecular Molecular Genetics Morphogenesis Multi-Drug Resistance Participant Pathogenesis Pharmacotherapy Plants Postdoctoral Fellow Process Research Research Personnel Resort Science Scientist Seeds Stress Response Signaling Surface Travel United States National Institutes of Health Vaccine Therapy Work antimicrobial bacterial community biophysical techniques career cell envelope design diversity and inclusion educational atmosphere gender diversity graduate student host-microbe interactions improved innovation insight interest meetings microbial community microbiome microbiota microorganism minority trainee multi-drug resistant pathogen new technology novel diagnostics novel therapeutics novel vaccines pathogen pathogenic bacteria peer posters programs resistant strain skills structural biology success symposium vaccine development

项目摘要

ABSTRACT This proposal seeks support for the 24th Gordon Research Conference (GRC) on Bacterial Cell Surfaces, the only meeting that connects cutting-edge research on cell envelope biology to the medically important downstream consequences of the bacterial cell surface. The 2022 meeting will be held June 26-July 1, 2022 at Mount Snow Resort, West Dover, VT and will have an associated Gordon Research Seminar (GRS). The meeting will cover topics that are of great interest to the biomedical community, especially in the current climate of the increased threat of multi-drug resistant pathogens, the need for novel vaccines, and the influence of the microbiome on human health. This GRC presents a diverse program in topics, model systems, and approaches combining biochemistry, molecular genetics, structural biology, cell biology, biophysics, imaging and modeling. There will be 9 sessions encompassing: (1) Exploring the Bacterial Cell Envelope; (2) Modifying the Bacterial Surface; (3) Cell Division and Morphogenesis; (4) Stress Responses and Signaling Across the Cell Envelope; (5) Mechanisms of Surface Recognition; (6) Transport through the Envelope; (7) Type VI and Type VII Secretion; (8) How the Surface Influences Bacterial Communities; and (9) Biophysical Methods to Improve Antimicrobial Therapies. The conference will focus on the latest, largely unpublished, and most exciting research on the assembly and function of the bacterial cell surface. We have selected a group of leading scientists, including a number of rising stars, and have closely considered seniority, gender, and diversity. To enhance the 2022 meeting, we have included roundtable discussions for junior scientists to engage with leaders of the field, the GRC Power Hour to examine issues of inclusion and diversity, and additional travel awards to support minority trainees. Additionally, we have further integrated the highly successful GRS for postdocs and graduate students with the GRC. Participants of the GRS will select 2 talks from the GRS for presentation at the GRC and the GRS co-chairs will present a summary of their meeting at the GRC opening. The traditional format of GRC meetings, with programmed discussion sessions and opportunities for informal gatherings in the afternoons and evenings, conveys a collegial atmosphere where interactions between attendees of all career stages are easily attained. The topics of this multifaceted conference are of practical interest to the biomedical community, and the mission of the NIH as it provides a platform for nucleating approaches to antibacterial strategies, vaccine development, and study of host-microbe interactions.

抽象的该提案寻求第 24 届戈登细菌细胞表面研究会议 (GRC) 的支持，唯一将细胞包膜生物学的前沿研究与医学上的重要研究联系起来的会议细菌细胞表面的下游后果。 2022年会议将于2022年6月26日至7月1日在佛蒙特州西多佛山雪山度假村将举办相关的戈登研究研讨会 (GRS)。这会议将涵盖生物医学界非常感兴趣的主题，特别是在当前气候下多重耐药病原体的威胁日益增加、对新型疫苗的需求以及微生物组对人类健康的影响。该 GRC 在主题、模型系统和方法方面提出了多样化的计划结合生物化学、分子遗传学、结构生物学、细胞生物学、生物物理学、成像和建模。共有 9 场会议，内容包括： (1) 探索细菌细胞包膜； (2) 改造细菌表面; (3)细胞分裂和形态发生； (4) 细胞膜上的应激反应和信号传导； (5) 表面识别机制； (6) 通过信封运输； (7) VI型和VII型分泌； (8) 表面如何影响细菌群落； (9) 提高抗菌性的生物物理方法疗法。会议将重点关注有关该领域最新的、大部分未发表的、最令人兴奋的研究细菌细胞表面的组装和功能。我们挑选了一批顶尖科学家，其中包括的新星数量，并仔细考虑了资历、性别和多样性。为增强2022年会议上，我们为初级科学家安排了圆桌讨论，以便与该领域的领导者、 GRC Power Hour 探讨包容性和多样性问题，并提供额外旅行奖励以支持少数族裔实习生。此外，我们还进一步整合了针对博士后和研究生的非常成功的 GRS 与GRC。 GRS的参与者将从GRS中选择2个演讲在GRC和GRS上进行演讲联合主席将在 GRC 开幕式上介绍会议摘要。 GRC会议的传统形式，下午和晚上有计划的讨论会和非正式聚会的机会，营造了一种学院氛围，各个职业阶段的参与者之间都可以轻松进行互动。这次多方面会议的主题符合生物医学界的实际利益，其使命 NIH 的重要地位，因为它为抗菌策略、疫苗开发、以及宿主-微生物相互作用的研究。