2022 Bacterial Cell Surfaces GRC/GRS

2022 细菌细胞表面GRC/GRS

基本信息

批准号：
10374358
负责人：
Michael Stephen Trent
金额：
$ 0.5万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-06-14 至 2023-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10374358
关键词：
Animals Anti-Bacterial Agents Area Atmosphere Award Bacteria Bacterial Drug Resistance Bacterial Physiology Basic Science Benign Biochemistry Biological Models Biological Process Biology Biophysics Career Choice Cell division Cell surface Cells Cellular biology Climate Columbidae Communities Development Disease Ensure Experimental Models Feedback Fertilization Fostering Generations Genetic Health Hour Human Image Knowledge Medical Mental Health Microbe Mission Modeling Molecular Molecular Genetics Morphogenesis Multi-Drug Resistance Participant Pathogenesis Pharmacotherapy Plants Postdoctoral Fellow Process Research Research Personnel Resort Science Scientist Seeds Stress Response Signaling Surface Travel United States National Institutes of Health Vaccine Therapy Work antimicrobial bacterial community biophysical techniques career cell envelope design diversity and inclusion educational atmosphere gender diversity graduate student host-microbe interactions improved innovation insight interest meetings microbial community microbiome microbiota microorganism minority trainee multi-drug resistant pathogen new technology novel diagnostics novel therapeutics novel vaccines pathogen pathogenic bacteria peer posters programs resistant strain skills structural biology success symposium vaccine development

项目摘要

ABSTRACT This proposal seeks support for the 24th Gordon Research Conference (GRC) on Bacterial Cell Surfaces, the only meeting that connects cutting-edge research on cell envelope biology to the medically important downstream consequences of the bacterial cell surface. The 2022 meeting will be held June 26-July 1, 2022 at Mount Snow Resort, West Dover, VT and will have an associated Gordon Research Seminar (GRS). The meeting will cover topics that are of great interest to the biomedical community, especially in the current climate of the increased threat of multi-drug resistant pathogens, the need for novel vaccines, and the influence of the microbiome on human health. This GRC presents a diverse program in topics, model systems, and approaches combining biochemistry, molecular genetics, structural biology, cell biology, biophysics, imaging and modeling. There will be 9 sessions encompassing: (1) Exploring the Bacterial Cell Envelope; (2) Modifying the Bacterial Surface; (3) Cell Division and Morphogenesis; (4) Stress Responses and Signaling Across the Cell Envelope; (5) Mechanisms of Surface Recognition; (6) Transport through the Envelope; (7) Type VI and Type VII Secretion; (8) How the Surface Influences Bacterial Communities; and (9) Biophysical Methods to Improve Antimicrobial Therapies. The conference will focus on the latest, largely unpublished, and most exciting research on the assembly and function of the bacterial cell surface. We have selected a group of leading scientists, including a number of rising stars, and have closely considered seniority, gender, and diversity. To enhance the 2022 meeting, we have included roundtable discussions for junior scientists to engage with leaders of the field, the GRC Power Hour to examine issues of inclusion and diversity, and additional travel awards to support minority trainees. Additionally, we have further integrated the highly successful GRS for postdocs and graduate students with the GRC. Participants of the GRS will select 2 talks from the GRS for presentation at the GRC and the GRS co-chairs will present a summary of their meeting at the GRC opening. The traditional format of GRC meetings, with programmed discussion sessions and opportunities for informal gatherings in the afternoons and evenings, conveys a collegial atmosphere where interactions between attendees of all career stages are easily attained. The topics of this multifaceted conference are of practical interest to the biomedical community, and the mission of the NIH as it provides a platform for nucleating approaches to antibacterial strategies, vaccine development, and study of host-microbe interactions.

抽象的该建议寻求支持第24届戈登研究会议（GRC）关于细菌细胞表面的支持，只有将有关细胞信封生物学的尖端研究与医学上重要的研究联系起来细菌细胞表面的下游后果。 2022会议将于2022年7月1日至7月1日在 VT西多佛（West Dover）的雪山胜地山度假村（Mount Snow Resort），将举行相关的戈登研究研讨会（GRS）。这会议将涵盖生物医学界引起极大兴趣的主题，尤其是在当前的气候下多药耐药病原体的威胁增加，新型疫苗的需求以及人类健康的微生物组。该GRC介绍了主题，模型系统和方法的多元化计划结合生物化学，分子遗传学，结构生物学，细胞生物学，生物物理学，成像和建模。将有9个会话包含：（1）探索细菌细胞包膜；（2）修改细菌表面; （3）细胞分裂和形态发生；（4）整个细胞包膜上的应力反应和信号传导；（5）表面识别的机制；（6）通过信封运输；（7）VI型和VII型分泌；（8）表面如何影响细菌群落；（9）改善抗菌剂的生物物理方法疗法。该会议将重点介绍最新的，在很大程度上未发表的，也是关于该的最激动人心的研究细菌细胞表面的组装和功能。我们选择了一群领先的科学家，包括冉冉升起的恒星数量，并密切考虑了资历，性别和多样性。增强2022 会议，我们包括了为初级科学家与该领域领导人互动的圆桌讨论 GRC Power Hour检查包容和多样性问题，以及支持少数派的其他旅行奖学员。此外，我们还进一步整合了博士后和研究生的非常成功的GRS 与GRC。 GRS的参与者将在GRC和GRS中选择2次演讲以进行演示联合主席将在GRC开幕式上介绍他们的会议。 GRC会议的传统格式，在下午和晚上进行编程的讨论会议和非正式聚会的机会，传达了一个大学氛围，其中所有职业阶段的与会者之间的互动很容易获得。这个多方面会议的主题对生物医学界和使命具有实际意义 NIH为抗菌策略，疫苗开发，疫苗开发提供了一个平台，并研究宿主 - 微叶相互作用。