Use of Novel Mobile Technology to Screen Sexual Partners for HIV and STIs

使用新型移动技术筛查性伴侣的艾滋病毒和性传播感染

基本信息

批准号：
9475241
负责人：
Ivan C Balan
金额：
$ 57.69万
依托单位：
NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-05-05 至 2020-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9475241
关键词：
Acquired Immunodeficiency Syndrome Antibodies Anus Balan Behavior Behavioral Biomedical Engineering Blood Blood Tests Caring Cellular Phone Computers Conscious Detection Development Devices Drops Early treatment Electronics Empathy Engineering Epidemic Feedback Frequencies Funding HIV HIV Infections HIV Seropositivity HIV/STD Hand Harm Reduction Health High Risk Woman Home environment Human immunodeficiency virus test Incidence Individual Infection Instruction Intervention Interview Interviewer LIF gene Lead Link Methods Monitor Motivation Newly Diagnosed Participant Phase Prevention Prevention strategy Recommendation Research Research Personnel Risk Risk Assessment Schools Screening procedure Sex Behavior Sexual Partners Shapes Symptoms Syphilis Technology Telephone Test Result Testing Time Universities Use Effectiveness Visit Work base condoms experience high risk high risk population high risk sexual behavior innovation men men who have sex with men mobile computing monitoring device novel novel strategies pre-exposure prophylaxis prevent public health relevance seroconversion sex risk sexual encounter skills smartphone Application social norm transgender women transmission process usability

项目摘要

DESCRIPTION (provided by applicant): Increasing incidence of HIV and STIs among men who have sex with men (MSM) and transgender women (TGW) highlight the need for novel approaches to reducing infections-especially among individuals who do not use condoms consistently. Our prior studies on the use of rapid HIV self-testing (ST) by MSM who regularly engage in high-risk sexual behavior, show that these men are willing to use ST with partners, avoid intercourse in situations where partners test HIV-positive, and, over time tend to reduce their high-risk sexual behavior. This proposed study expands this line of research by exploring the use of a new device, the mChip dongle. Developed at the Columbia University School of Engineering, this device uses smartphone technology to analyze a drop of blood and test it for HIV and syphilis antibodies. The mChip dongle brings more precision to ST, tests for HIV and syphilis and potentially other STIs, and can capitalize on smartphone technology to provide clearer user instructions, on-hand information about HIV/STI, remote monitoring of the its use, and linkage of newly diagnosed individuals to care. For this proposed quantitative and qualitative study, we will again focus on HIV-uninfected MSM and TGW with multiple sexual partners who know how to prevent HIV infection, yet engage in high-risk sexual behavior. The Specific Aims are to: 1) Assess acceptability among MSM and TGW of using the mChip dongle to test sexual partners; 2) Optimize the smartphone app and mChip dongle for home use; and 3) Assess the feasibility of using the mChip dongle to test sexual partners, including: a) frequency of use of the mChip dongle with sexual partners over 3 months; b) factors associated with mChip dongle use or non-use; c) condom use with partners who were not screened vs. partners screened HIV or STI- negative with the mChip dongle; and d) factors associated with changes in sexual risk behavior over 3 months. The study consists of two phases. In Phase 1A, 60 participants will undergo a quantitative, qualitative, and skill-demonstration assessment (using the mChip dongle in front of the interviewer) in a single study visit. Phase 1A findings wil inform Phase 1B, which focuses on revising the smartphone app and mChip dongle for home users, as well as revisions to the Phase 2 assessment. In Phase 2A, 80 new participants will undergo a baseline quantitative and skill-demonstration assessment in order to screen for 50 participants who will be invited into the Phase 2B 3-month study. These 50 participants will be provided with an mChip dongle and given the choice to use it to screen sexual partners. After 3 months participants will undergo a quantitative and qualitative interview about experiences using (or not using) the mChip dongle with partners. This study will capitalize on a critical juncture in the development of the mChip dongle by systematically engaging its intended users in offering feedback to the engineering team on how to optimize its usability and acceptability among high-risk populations. This study will also allow us to assess the feasibility of conducting a larger and longer trial to develop and test an mChip-based harm-reduction intervention.

描述（通过应用程序证明）：艾滋病毒敏人的发病率与男性（MSM）和变性妇女（TGW）发生性关系，以减少我们先前使用避孕套的人的感染。艾滋病毒的自我测试（ST）是MSM的，他们经常在伴侣测试HIV阳性的地方进行性交，并且随着时间的流逝，倾向于减少其高风险的性行为。该设备的工程学院使用智能手机技术来分析血液的滴滴，并为梅毒带来的艾滋病毒和梅毒所带来的IS。新诊断的人的联系再次关注HIV-Uninf与知道可以预防艾滋病毒感染的多次性伴侣，但特定的目标是对艺术的智能手机应用程序和MCHIP加密狗用于家庭使用； 3）使用MCHIP加密狗评估盛宴，以测试性伴侣：a）与MCHIP加密狗使用的性伴侣因素的频率伴侣没有被筛选的伴侣筛选艾滋病毒或与MCHIP加密狗的几个月。在家庭用户的智能手机应用程序和MCHIP加密狗上，以及第2阶段评估的修订。三个月的研究。系统地吸引其预期的用户向工程团队提供有关如何优化高风险普及的TY和可接受性的反馈。损害回合的间隔。