Genetics of Monocyte Killing by Bacteria

细菌杀死单核细胞的遗传学

• 批准号: 8206789
• 负责人: HOWARD A SHUMAN
• 金额: $ 54.33万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-06-15 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8206789
• 关键词: Actins; Acute Pneumonia; Alleles; Alveolar Macrophages; Bacteria; Binding; Biochemical; Bioinformatics; Biological; Breathing; Cell Line; Cells; Coiled-Coil Domain; Complex; Defect; Disease; Dominant-Negative Mutation; Ectopic Expression; Endoplasmic Reticulum; Ensure; Environment; Event; Exhibits; Funding; Genes; Genetic; Golgi Apparatus; Growth; Human; Individual; Infection; Legionella; Legionella pneumophila; Legionnaires' Disease; Leukocytes; Lung; Lysosomes; Mammalian Cell; Measures; Membrane; Microbial Biofilms; Modeling; Molecular; Organelles; PTPRC gene; Pathway interactions; Phagosomes; Phenotype; Phosphoric Monoester Hydrolases; Phosphotransferases; Plumbing; Property; Protein Family; Protein Tyrosine Kinase; Protein Tyrosine Phosphatase; Protein translocation; Proteins; Research; Role; SNAP receptor; Saccharomyces cerevisiae; Small Interfering RNA; Sorting - Cell Movement; Source; System; Testing; Vacuolar Protein Sorting; Vacuole; Vesicle; Water; Work; Yeasts; aerosolized; antimicrobial; bacterial genetics; base; inhibitor/antagonist; killings; macrophage; monocyte; mutant; novel; null mutation; pathogen; polymerization; tool; trafficking