Bioinformatics and Genomics Core

生物信息学和基因组学核心

• 批准号: 7678842
• 负责人: Bruno Sobral
• 金额: $ 15.61万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-03-01 至 2009-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7678842
• 关键词: Bioinformatics; Biological; Biology; Class; Computer software; DNA; Environment; Funding; Genomics; Information Management; Information Systems; Institutes; Laboratories; Measurement; Molecular; Organism; Performance; Research; Research Infrastructure; Research Project Grants; Resource Sharing; Sampling; Training; Virginia; data acquisition; laboratory facility; member; pathogen; programs; protein metabolite; research facility

The Virginia Bioinformatics Institute (VBI) at Virginia Tech proposes to serve as the Bioinformatics/Genomics Core Research Facility for the mid-Atlantic RCE. VBI was created by the Commonwealth of Virginia as a world-class bioinformatics research center and a shared resource and its research programs center on the ¿disease triangle¿, or host-pathogen-environment interactions. Thus, VBI is scientifically focused on pathosystems biology, through comprehensive quantitative measurements of molecular components of living systems. Specifically, to serve the genomics core component, VBI will provide high-performance laboratory infrastructure for analysis of biological samples with respect to DNA, RNA, proteins and metabolites via VBl¿s Core Laboratory Facility. To serve as the bioinformatics core, VBI will provide high-Performance computational and information management needs via VBl¿s Core Computational Facility and it will evolve, deploy and support VBl¿s software information system for PathoSystems Biology-called PafhPorf, a DOD-funded project-to enable data acquisition, storage, analysis, curation, and integration for the RCE members and beyond. Finally, VBI will train and educate RCE research project constituencies on computing and information systems use for their RCE research objectives.

弗吉尼亚理工大学的弗吉尼亚生物信息学研究所 (VBI) 建议充当 大西洋中部 RCE 生物信息学/基因组学核心研究设施由 VBI 创建。 弗吉尼亚联邦作为世界一流的生物信息学研究中心和共享资源及其 研究项目以 ¿疾病三角?? ，或宿主-病原体-环境相互作用。 VBI 通过全面的定量测量，科学地专注于病理系统生物学 具体来说，VBI 将服务于基因组学核心组件。 提供高性能实验室基础设施，用于分析生物样本的 DNA， RNA、蛋白质和代谢物通过 VBl¿核心实验室设施作为生物信息学核心， VBI将通过VBI提供高性能计算和信息管理需求分数 计算设施及其将发展、部署和支持 VBl¿的软件信息系统 PathoSystems Biology 称为 PafhPorf，是国防部资助的一个项目，旨在实现数据采集、存储、 最后，VBI 将为 RCE 成员及其他成员提供培训和教育。 RCE 研究项目选区用于 RCE 研究的计算和​​信息系统 目标。