Administrative Supplements for Equipment Purchases
设备采购行政补充
基本信息
- 批准号:10794680
- 负责人:
- 金额:$ 9.99万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-09-01 至 2025-08-31
- 项目状态:未结题
- 来源:
- 关键词:26S proteasomeAdministrative SupplementAffectAwardBiochemicalBiological ModelsBiologyBrainCRISPR/Cas technologyCaenorhabditis elegansCell CycleCell divisionCentriolesCentrosomeCompensationDefectDetectionDevelopmentDiseaseEmbryoEnsureEquipmentExhibitsFundingGeneticGenomic InstabilityGoalsHealthcareHomeostasisHumanKnowledgeMalignant NeoplasmsMeasurementMediatingMicrocephalyMicrotubule-Organizing CenterMusMutationNational Institute of General Medical SciencesParentsPredispositionProtein AnalysisProteinsProteolysisQuantitative MicroscopyRegulation of ProteolysisRequest for ProposalsResearchResolutionRoleSignal TransductionSystemTestingTherapeutic InterventionWorkanaphase-promoting complexciliopathydaughter cellequipment acquisitiongenome editinggenome integrityhuman diseaseimaging systemin vivoin vivo Modelmutantnanoparent projectrecruitsuccesstransmission processtumorigenesisubiquitin ligaseubiquitin-protein ligase
项目摘要
Project Summary
Under the current NIGMS R15 research award (1R15GM147857-01), this proposal requests
supplemental equipment funds that will be used to replace an old broken Odyssey Infrared
Imaging system. The parent project focuses on the Proteolytic Regulation of Centrosome
Proteins. The requested equipment is essential for carrying out the experimental plans for
the Quantitative and Qualitative analysis of proteins successfully. The accurate
measurement of protein levels and detection of proteins in low abundance require enhanced
sensitivity and resolution. This administrative supplement fund will allow us to purchase Odyssey
M Imaging system. This new imaging system will replace a broken Odyssey Infrared scanner
and offer technical upgrades in the sensitivity and resolution of signal detection, which will serve
a critical role in the success of the parent R15 project.
项目概要
根据当前的 NIGMS R15 研究奖 (1R15GM147857-01),该提案要求
补充设备资金将用于更换旧的损坏的奥德赛红外
成像系统。父项目重点关注中心体的蛋白水解调节
蛋白质。所需的设备对于执行实验计划至关重要
成功地进行了蛋白质的定量和定性分析。准确的
蛋白质水平的测量和低丰度蛋白质的检测需要增强
灵敏度和分辨率。这笔行政补充基金将允许我们购买奥德赛
M 成像系统。这种新的成像系统将取代损坏的奥德赛红外扫描仪
并对信号检测的灵敏度和分辨率进行技术升级,这将服务于
在母公司 R15 项目的成功中发挥着关键作用。
项目成果
期刊论文数量(2)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Site-specific phosphorylation of ZYG-1 regulates ZYG-1 stability and centrosome number.
- DOI:10.1016/j.isci.2023.108410
- 发表时间:2023-12-15
- 期刊:
- 影响因子:5.8
- 作者:Medley, Jeffrey C.;Yim, Rachel N.;DiPanni, Joseph;Sebou, Brandon;Shaffou, Blake;Cramer, Evan;Wu, Colin;Kabara, Megan;Song, Mi Hye
- 通讯作者:Song, Mi Hye
kin-3 genetically suppresses sur-6 in centrosome assembly during Caenorhabditis elegans embryogenesis.
- DOI:10.17912/micropub.biology.000791
- 发表时间:2023
- 期刊:
- 影响因子:0
- 作者:Medley, Jeffrey C;Song, Mi Hye
- 通讯作者:Song, Mi Hye
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Mi Hye Song其他文献
Mi Hye Song的其他文献
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{{ truncateString('Mi Hye Song', 18)}}的其他基金
Regulation of Centrosome Assembly by Phosphorylation
磷酸化调节中心体组装
- 批准号:
8290705 - 财政年份:2012
- 资助金额:
$ 9.99万 - 项目类别:
Regulation of Centrosome Assembly by Phosphorylation
磷酸化调节中心体组装
- 批准号:
8811609 - 财政年份:2012
- 资助金额:
$ 9.99万 - 项目类别:
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