Improving HIV Prevention Services among Socioeconomically Disadvantaged Cis-gender Women

改善社会经济弱势顺性别女性的艾滋病毒预防服务

基本信息

批准号：
10772735
负责人：
Jenell S Coleman
金额：
$ 21.62万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-08-05 至 2024-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10772735
关键词：
AIDS prevention Acute Address Administrative Supplement African American Belief Black race Breast Feeding Caring Child City Planning Clinic Clinical Counseling Data Decision Making Development Diagnosis Discipline of obstetrics Enrollment Ensure Epidemic Ethnic Origin Ethnic Population Family Feedback Gender Guidelines Gynecology HIV HIV Infections HIV Seropositivity HIV risk Hispanic Home Human immunodeficiency virus test Infant Interview Knowledge Latino Live Birth Methods Newly Diagnosed Outcome Parents Patients Perinatal Perinatal transmission Personal Satisfaction Persons Population Postpartum Period Pregnancy Pregnant Women Prenatal care Prevention Provider Recommendation Recording of previous events Research Risk Schedule Sexual Partners Surveys Testing Time United States Vagina Visit Woman antiretroviral therapy barrier to testing cis-female effectiveness/implementation trial evidence base health of the mother high risk implementation research improved infection rate male obstetric care perinatal HIV pre-exposure prophylaxis pregnant prevent prevention service racial disparity racial population seroconversion social culture socioeconomic disadvantage testing uptake transmission process uptake virtual

项目摘要

Eliminating perinatal HIV in the U.S. is within reach. The overall rate of perinatal HIV infections in 2020 was 1:100,000, but there were disparities by race and ethnicity. For example, the rate of infections among Black/African American infants was 3.8:100,000, which is four and nearly 13 times the rates among Hispanic/Latino and White persons, respectively. To reduce the number of babies born with HIV, we must ensure pregnant women and their partners have access to HIV testing and PrEP. Opt-out HIV testing of the pregnant person is an effective evidenced-based strategy to prevent perinatal HIV transmission; however, this approach does not identify or address those at risk of HIV seroconversion during pregnancy. Ending the HIV epidemic may not be successfully achieved inn certain populations without the intentional engagement of the male partner during the pregnancy period. Male partner engagement benefits a wide range of outcomes related to maternal, child, and family wellbeing. U.S. guidelines recommend that partners of pregnant women undergo HIV testing when their status is unknown. However, this recommendation has not been implemented due to a lack of successful implementation research. Whereas the parent hybrid effectiveness-implementation trial (R01MH132146) addresses barriers to HIV testing and PrEP uptake among a non-pregnant population, this administrative supplement focuses on socioeconomically disadvantaged pregnant persons and their male partners. We aim to conduct a pilot mixed methods study to engage male partners in HIV prevention services during prenatal care. We hypothesize that the uptake of HIV prevention services (i.e., counseling, HIV testing, and PrEP) will increase with the engagement of the male partner (in-person or virtually) and the assessment of their HIV risk. This project will assess the perceived risk of HIV infection among the pregnant person and their male sexual partner with a validated survey. Next, we will offer male partners home-based HIV testing. Last, we will identify facilitators and barriers to testing uptake using in-depth interviews.

在美国消除围产期艾滋病毒是可以实现的。围产期艾滋病毒感染率总体 2020 年是 1:100,000，但种族和民族之间存在差异。例如，比率黑人/非裔美国婴儿的感染率为 3.8:100,000，是四倍和近 13 倍分别是西班牙裔/拉丁裔和白人的比率。为了减少婴儿数量出生时就携带艾滋病毒，我们必须确保孕妇及其伴侣能够接受艾滋病毒检测并 PrEP。选择退出对孕妇进行艾滋病毒检测是预防艾滋病毒感染的一种有效的循证策略围产期艾滋病毒传播；然而，这种方法并不能识别或解决那些有感染艾滋病毒风险的人怀孕期间的血清转化。结束艾滋病毒流行可能无法成功实现某些人群在怀孕期间没有男性伴侣的故意参与时期。男性伴侣的参与有益于与孕产妇、儿童和儿童相关的广泛结果。家庭幸福。美国指南建议孕妇的伴侣接受艾滋病毒检测当他们的状态未知时。然而，由于以下原因，这一建议并未得到落实：缺乏成功的实施研究。而父级混合有效性-实施试验 (R01MH132146) 解决了非怀孕人群中 HIV 检测和 PrEP 摄取的障碍人口，该行政补充的重点是社会经济地位处于不利地位的孕妇个人及其男性伴侣。我们的目标是进行一项试点混合方法研究，以吸引男性参与产前护理期间艾滋病毒预防服务的合作伙伴。我们假设 HIV 的吸收随着人们的参与，预防服务（即咨询、艾滋病毒检测和 PrEP）将会增加男性伴侣（面对面或虚拟）及其艾滋病毒风险评估。该项目将评估孕妇及其男性性伴侣感染艾滋病毒的感知风险经验证的调查。接下来，我们将为男性伴侣提供家庭艾滋病毒检测。最后，我们将识别使用深度访谈进行测试的促进因素和障碍。