Improving Care of Persons with Cognitive Impairment and their Caregivers

改善对认知障碍患者及其护理人员的护理

基本信息

批准号：
7627330
负责人：
Yueh-Feng Yvonne Lu
金额：
$ 8.83万
依托单位：
INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-06-01 至 2011-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7627330
关键词：
Activities of Daily Living Affect Aging Alzheimer&apos s Disease Behavior Behavior Therapy Behavioral Biometry Caregivers Caring Clinical Clinical Research Clinical Trials Conflict (Psychology)Data Dementia Development Discipline of Nursing Doctor of Philosophy Early treatment Elderly Emotional Emotions Ensure Environment Equilibrium Future Goals Impaired cognition Impairment Indiana Institutes Intervention Lead Learning Mentors Mentorship Methods Motivation Nursing Research Outcome Outcome Measure Patients Perception Persons Physical activity Pilot Projects Population Qualitative Research Quality of life Randomized Clinical Trials Randomized Controlled Clinical Trials Research Research Activity Research Methodology Research Project Grants School Nursing Scientist Self Management Staging Structure Telephone Testing Time Training Universities aging population care giving burden career career development caregiving cognitive function cohort depression design disability episodic memory impairment high risk improved interest meetings mild neurocognitive impairment neuropsychological patient oriented research peer premature prevent productivity loss programs skills

项目摘要

DESCRIPTION (provided by applicant): The candidate is a PhD nursing research scientist focusing on behavioral interventions to improve the care of older adults with mild cognitive impairment. The candidate seeks to obtain additional training in neuropsychological assessment, mixed methods biostatistics, multi-component clinical interventions, and collaborative clinical research in order to become an independent nursing scientist. She has assembled a multi-disciplinary mentorship team to assist her in her training and research activities. Mild cognitive impairment (MCI) affects as many as 20% of older adults, nearly three times the number affected by dementia. Previous studies have shown that persons with MCI are at high risk for developing Alzheimer disease (AD). MCI is associated with loss of productivity and difficulty in engaging in meaningful activities even before the development of dementia. These losses are associated with both premature disability and depression. There is a need for interventions targeted at the stage of MCI because at this early stage of cognitive decline, patients and their caregivers may have a critical window to develop important self-management skills that will prevent premature disability and disengagement. In the proposed study, the candidate will lead the development of a pilot study of the "daily enhancement of meaningful activities" (DEMA) intervention. It is hypothesized that identification of daily meaningful activities and engaging in these activities can improve physical and emotional function as well as quality of life. It is also hypothesized that the DEMA intervention will reduce care giving burden. Specific aims of this pilot study are: (1) to design and field-test the DEMA intervention among MCI patient caregiver dyads to assess desirability, feasibility, and acceptability; and (2) to obtain preliminary data on participation rates, effect size, and outcome measures for the DEMA intervention to plan for a future randomized controlled clinical trial.

描述（由申请人提供）：候选人是一名护理研究科学家博士，专注于行为干预，以改善患有轻度认知障碍的老年人的护理。候选人寻求获得神经心理学评估、混合方法生物统计学、多成分临床干预和协作临床研究方面的额外培训，以便成为一名独立的护理科学家。她组建了一个多学科的指导团队来协助她的培训和研究活动。多达 20% 的老年人患有轻度认知障碍 (MCI)，几乎是痴呆症患者人数的三倍。先前的研究表明，患有 MCI 的人患阿尔茨海默病 (AD) 的风险很高。即使在痴呆症发生之前，MCI 就与生产力下降和难以从事有意义的活动有关。这些损失与过早残疾和抑郁症有关。需要针对 MCI 阶段进行干预，因为在认知能力下降的早期阶段，患者及其护理人员可能有一个关键的窗口来发展重要的自我管理技能，以防止过早残疾和脱离。在拟议的研究中，候选人将领导“每日增强有意义的活动”（DEMA）干预的试点研究的开发。据推测，识别日常有意义的活动并参与这些活动可以改善身体和情感功能以及生活质量。还假设 DEMA 干预将减轻护理负担。本试点研究的具体目标是：(1) 设计并现场测试 MCI 患者护理人员双人组中的 DEMA 干预，以评估其可取性、可行性和可接受性； (2) 获得 DEMA 干预的参与率、效应大小和结果测量的初步数据，以规划未来的随机对照临床试验。