Program for AIDS Clinical Research Training (PACRT)

艾滋病临床研究培训计划 (PACRT)

• 批准号: 7636799
• 负责人: Kenneth Alan Freedberg
• 金额: $ 32.9万
• 依托单位: HARVARD SCHOOL OF PUBLIC HEALTH
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-09-30 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7636799
• 关键词: Acquired Immunodeficiency Syndrome; Clinical Research; Research Training; Training Programs; programs

DESCRIPTION (provided by applicant): In the past decade, dramatic advances in the understanding of HIV and its therapy have transformed HIV into a chronic, treatable disease. These advances, however, raise critical and complex questions linking basic research, clinical epidemiology, clinical trials, and outcomes research. The goal of the Harvard Program for AIDS Clinical Research Training (PACRT), which has successfully trained clinical investigators for 14 years, is to provide br6ad training in quantitative research methodologies and a closely supervised "'research experience to infectious disease and other physicians at an early stage in their careers, as well as to pre-doctoral PhD students whose focus is on HIV clinical research. This training will prepare both groups to conduct clinical research of the highest quality and of direct relevance to the prevention and treatment of HIV infection, and it will prepare them for the next phase of development as independent investigators. The post-doctoral candidates will receive two years of research training under the close supervision of one or more of the 15 program faculty members. Program faculty include internationally recognized investigators in the fields of clinical virology, epidemiology, clinical trials, decision-analysis, cost-effectiveness analysis, outcomes research, and medical anthropology. Both pre-doctoral and post-doctoral trainees will receive didactic training through coursework at Harvard School of Public Health or other Harvard University sites. Primary performance sites for the post-doctoral fellows will be the Massachusetts General Hospital, Beth Israel Deaconess Medical Center, Brigham and Women's Hospital, and Harvard Medical School. In its first 14 years, this program has helped develop and launch a new cadre of independent investigators studying a broad array of clinical research issues in HIV. It's trainees have published over 100 peer reviewed manuscripts, and the success of its fellows in obtaining continued NIH support places it among the top programs in the country. The proposed continuation will allow the PACRT to help train the next generation of highly successful investigators to address the complex and evolving issues arising today in HIV clinical research.

描述（由申请人提供）：在过去的十年中，对艾滋病毒及其治疗的认识取得了巨大进展，已将艾滋病毒转变为一种慢性、可治疗的疾病。然而，这些进展提出了连接基础研究、临床流行病学、临床试验和结果研究的关键而复杂的问题。哈佛艾滋病临床研究培训计划 (PACRT) 已成功培训临床研究人员 14 年，其目标是提供定量研究方法方面的 br6ad 培训，并在严格监督下向传染病和其他医生提供“研究经验”。职业生涯的早期阶段，以及专注于艾滋病毒临床研究的博士前博士生，本次培训将使两个小组做好准备，开展与艾滋病毒感染的预防和治疗直接相关的最高质量的临床研究，它会准备博士后候选人将在 15 名项目教员（包括临床病毒学领域国际公认的研究人员）的密切监督下接受两年的研究培训。 、流行病学、临床试验、决策分析、成本效益分析、结果研究和医学人类学。博士前和博士后学员都将通过哈佛大学公共卫生学院或哈佛大学其他分校的课程接受教学培训。博士后研究员的主要工作地点将是马萨诸塞州总医院、贝斯以色列女执事医疗中心、布莱根妇女医院和哈佛医学院。在最初的 14 年里，该项目帮助培养和启动了一支新的独立研究人员队伍，研究艾滋病毒的广泛临床研究问题。它的学员发表了 100 多篇同行评审的手稿，其研究员成功获得 NIH 的持续支持，使其跻身于美国顶级项目之列。拟议的延续将使 PACRT 能够帮助培训下一代非常成功的研究人员，以解决当今艾滋病毒临床研究中出现的复杂且不断变化的问题。