A Multicomponent Intervention to Increase HIV Risk Perceptions and PrEPInitiation among Black Men Who Have Sex With Men

提高男男性行为黑人的艾滋病毒风险认知和预防准备的多成分干预措施

• 批准号: 10689428
• 负责人: Derek Tramel Dangerfield II
• 金额: $ 18.41万
• 依托单位: GEORGE WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-24 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10689428
• 关键词: AIDS prevention; Acquired Immunodeficiency Syndrome; Address; Age; Appointments and Schedules; Award; Baltimore; Behavior; Behavioral; California; Cessation of life; Cities; Clinical; Communities; Data; Data Collection; Development; Discrimination; Disease susceptibility; Doctor of Philosophy; Educational workshop; Elements; Evaluation; Exposure to; Focus Groups; Fostering; Future; Guidelines; HIV; HIV Infections; HIV Seronegativity; HIV risk; HIV/STD; Health; Health Personnel; Health Promotion; Healthcare; Incidence; Infection; Insurance; Insurance Coverage; Intervention; Judgment; Lead; Life; Life Cycle Stages; Maryland; Medical; Mentors; Mentorship; Methods; Modeling; Opioid; Patients; Perception; Phase; Population; Predisposition; Prevention education; Prevention strategy; Principal Investigator; Procedures; Provider; Public Health Schools; Recording of previous events; Reduce health disparities; Research; Research Methodology; Research Personnel; Research Training; Risk; Risk Behaviors; Role; Sampling; School Nursing; Scientist; Self Efficacy; Services; Sex Behavior; Statistical Data Interpretation; Techniques; Technology; Telemedicine; Testing; Time; TimeLine; Training; Universities; Work; acceptability and feasibility; base; behavioral/social science; black men who have sex with men; career; cohort; data standards; design; diaries; efficacy trial; experience; generation difference; health belief; high risk; implementation science; improved; innovation; interest; medical schools; men who have sex with men; motivational enhancement therapy; multi-component intervention; peer; peer support; pilot test; pre-exposure prophylaxis; preference; prevent; research and development; risk perception; sexual risk behavior; skills; smartphone Application; social stigma; theories; therapy design; training opportunity; transmission process; uptake; willingness

PROJECT SUMMARY/ABSTRACT Tragically, HIV infections among Black men who have sex with men (BMSM) in the U.S. persist. Despite the availability and interest in pre-exposure prophylaxis (PrEP), effective uptake among BMSM remains low. It is imperative to mitigate barriers to PrEP initiation among this group, which could require HIV interventions that incorporate behavioral, biomedical, and structural strategies. The proposed theory-guided, multi-component intervention is designed to enhance HIV risk perceptions and increase PrEP initiation among BMSM in Baltimore City, using an existing mobile smartphone application along with peer change agents to record and review sexual risk behaviors and encourage PrEP initiation. The proposed research and training plan in this Mentored Research Scientist Developmental Award (K01) proposal will provide the principal investigator, Derek T. Dangerfield II, PhD, with the skills needed in intervention design to develop into a productive, independent investigator. The research and training aims proposed address a critical gap in HIV prevention; it is well established that extant work has failed to substantially lower infections among BMSM throughout the U.S. To strategically advance these training aims, this K01 proposal is crafted to facilitate professional development and research capacities as a rising independent investigator. Targeted course work, didactic workshops, and in-depth mentorship from experts in the domains of clinical intervention design, life course theoretical approaches to health, and statistical analysis are incorporated to facilitate hands-on opportunities to apply newly developed skills. The combined use of technology, peers, and PrEP leverages existing relevant prevention strategies for a multi-component intervention. This research is innovative and timely as it responds to federal and academic calls for carefully considerate, interdisciplinary interventions to reduce HIV incidence among priority populations. The aims of this proposal incorporate qualitative and quantitative research methods to explore the preferences of the components of an intervention to increase PrEP initiation among the population. This research has implications for understanding whether the methods used in this intervention can be applied in clinical settings or can be applied in peer-based settings to circumvent the barriers of traditional healthcare engagement. Dr. Dangerfield will be primarily mentored by senior investigator Jason Farley, PhD, MPH, ANP-BC, FAAN at the Johns Hopkins School of Nursing, with additional mentoring from Drs. Chris Beyrer (Johns Hopkins Bloomberg School of Public Health), Ricky Bluthenthal (University of Southern California Keck School of Medicine), and Renata Arrington-Sanders (Johns Hopkins School of Medicine). Through research and didactic mentoring and training, Dr. Dangerfield will build upon his expertise in behavioral social science to develop a successful career in designing high-impact, multicomponent clinical interventions and reduce health disparities.

项目摘要/摘要 可悲的是，美国与男性发生性关系的黑人感染（BMSM）仍然存在。 尽管对暴露前预防具有可用性和兴趣（PREP），但在BMSM中有效吸收 保持低。必须减轻该组的准备障碍，这可能需要艾滋病毒 结合行为，生物医学和结构策略的干预措施。提出的理论引导， 多组分干预旨在增强艾滋病毒风险感知并增加准备 巴尔的摩市的BMSM，使用现有的移动智能手机应用程序以及同行更改代理 记录和审查性风险行为并鼓励准备启动。拟议的研究和培训 这项指导的研究科学家发展奖（K01）提案中的计划将为校长提供 调查员Derek T. Dangerfield II博士，其干预设计所需的技能将 生产性，独立研究者。研究和培训的目的旨在解决艾滋病毒中的关键差距 预防;众所周知，现有的工作未能大大降低BMSM的感染 在整个美国，为了促进这些培训目标，该K01提案是为了促进的 专业发展和研究能力是一名崛起的独立研究者。有针对性的课程工作， 临床干预设计领域专家的教学研讨会和深入的指导 课程理论上的健康方法和统计分析均已纳入以促进动手 运用新发展技能的机会。技术，同行和预备利用的联合使用 现有的相关预防策略用于多组分干预。这项研究是创新的， 及时响应联邦和学术要求，要求精心体贴，跨学科的干预措施 减少优先人群中的艾滋病毒发病率。该提案的目的包括定性和 定量研究方法探索干预措施的组成部分的偏好以增加 人口的准备启动。这项研究对理解方法是否有影响 在此干预措施中使用的 规避传统医疗保健参与的障碍。 Dangerfield博士将主要由 高级调查员Jason Farley博士，MPH，ANP-BC，Johns Hopkins护理学院的FAAN，与 DRS的额外指导。克里斯·贝勒（Chris Beyrer）（约翰·霍普金斯彭博公共卫生学院），里奇 Bluthenthal（南加州大学凯克医学院）和Renata Arrington-Sanders（Johns 霍普金斯医学院）。通过研究和教学指导和培训，Dangerfield博士将建造 凭借他在行为社会科学方面的专业知识，以发展设计高影响力的事业， 多组分临床干预措施并减少健康差异。

项目成果

Conducting Virtual, Synchronous Focus Groups Among Black Sexual Minority Men: Qualitative Study.

• DOI: 10.2196/22980
• 发表时间: 2021-02-08
• 期刊: JMIR public health and surveillance
• 影响因子: 8.5
• 作者: Dangerfield Ii DT;Wylie C;Anderson JN
• 通讯作者: Anderson JN

Community engagement and linkage to care efforts by peer community-health workers to increase PrEP uptake among sexual minority men.

• DOI: 10.1111/phn.12887
• 发表时间: 2021-09
• 期刊: Public health nursing (Boston, Mass.)
• 作者: Farley JE;Dangerfield DT 2nd;LaRicci J;Sacamano P;Heidari O;Lowensen K;Jennings JM;Tobin KE
• 通讯作者: Tobin KE