Administrative Core

行政核心

• 批准号: 10724220
• 负责人: Dan H. Barouch
• 金额: $ 15.5万
• 依托单位: BETH ISRAEL DEACONESS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-11 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10724220
• 关键词: Communication; Ensure; Financial Support; Goals; HIV vaccine; HIV-1; Logistics; National Institute of Allergy and Infectious Disease; Persons; Program Efficiency; Program Research Project Grants; Research Personnel; Structure; Treatment Efficacy; Vaccine Therapy; meetings; multiple omics; neutralizing antibody; operation; programs; symposium; timeline

Centralized administration is critical for efficient program management, coordination, and execution. Core A (Administrative Core) will provide all the logistic, scientific, managerial, and financial support to facilitate and to coordinate the studies described in this P01 program. Core A will ensure that all the Projects and Cores function optimally and adhere to the timelines and milestones described in this proposal. Core A will organize conference calls every two weeks and regular in-person meetings, maintain regulatory approvals, provide fiscal and logistic oversight, manage subcontracts, and coordinate meetings with the Scientific Advisory Board (SAB) and NIAID Program Officials to support this P01 program. This detailed administration and management structure will ensure that all the studies remain focused on the overall objective to define mechanisms of therapeutic efficacy of bNAbs and vaccines for HIV-1. To accomplish these goals, we propose the following four Specific Aims: Aim 1. To coordinate communications, interactions, and operations among investigators, Projects, and Cores to facilitate the overall progress and goals of this P01 program Aim 2. To ensure and to maintain regulatory compliance Aim 3. To provide detailed financial oversight and management Aim 4. To coordinate meetings with the SAB and NIAID Program Officials

集中管理对于高效的项目管理、协调和执行至关重要。核心A （行政核心）将提供所有后勤、科学、管理和财务支持，以促进 并协调本 P01 计划中描述的研究。核心 A 将确保所有项目和 核心功能最佳，并遵守本提案中描述的时间表和里程碑。核心A将 每两周组织一次电话会议并定期举行面对面会议，维护监管部门的批准， 提供财政和后勤监督，管理分包合同，并与科学咨询协调会议 董事会 (SAB) 和 NIAID 计划官员支持该 P01 计划。这个详细的管理和 管理结构将确保所有研究仍然集中于确定总体目标 bNAb 和 HIV-1 疫苗的治疗功效机制。为了实现这些目标，我们建议 以下四个具体目标： 目标 1. 协调研究者、项目和核心之间的沟通、互动和操作，以 促进P01计划的整体进展和目标 目标 2. 确保并维持合规性 目标 3. 提供详细的财务监督和管理 目标 4. 协调与 SAB 和 NIAID 项目官员的会议