Massachusetts AI and Technology Center for Connected Care in Aging and Alzheimer's Disease (MAITC): Pilot (AD ADRD Focus)

马萨诸塞州老龄化和阿尔茨海默病互联护理人工智能和技术中心 (MAITC)：试点（AD ADRD 焦点）

• 批准号: 10675688
• 负责人: Deepak Ganesan
• 金额: $ 187.15万
• 依托单位: UNIVERSITY OF MASSACHUSETTS AMHERST
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-30 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10675688
• 关键词: Acceleration; Acute; Address; Affect; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; American; Applications Grants; Area; Artificial Intelligence; Assisted Living Facilities; Behavior; Behavior Therapy; Businesses; Caregiver Burden; Caregivers; Caring; Clinical; Cognitive deficits; Collaborations; Development; Discipline; Disease Progression; Elderly; Enhancement Technology; Ensure; Ethnic Origin; Evaluation; Family; Fostering; Geriatrics; Goals; Grant; Health; Healthcare Systems; Home; Home environment; Impaired cognition; Industry; Industry Collaboration; Institution; Institutional Review Boards; Letters; Massachusetts; Medical; Medication Errors; Medicine; Memory; Mentors; Mentorship; Methods; Movement; Neurology; Occupational activity of managing finances; Outcome; Patients; Persons; Pilot Projects; Play; Process; Psychiatry; Quality of life; Race; Recording of previous events; Reproducibility; Research; Research Personnel; Resources; Risk; Role; Safety; Schools; Shapes; Small Business Innovation Research Grant; Support System; Syndrome; Technical Expertise; Technology; Technology Transfer; Testing; Training Programs; Translating; United States; Universities; Work; career; caregiving; clinical care; clinical decision-making; clinically relevant; commercialization; comorbidity; computer science; connected care; ethnic diversity; experience; flexibility; follow-up; human subject; improved; individual patient; innovation; insight; motor deficit; new technology; novel; participant safety; protective behavior; racial diversity; recruit; response; tool; translational goal

PROJECT SUMMARY: AD/ADRD Pilot Core The Alzheimer's Disease and Related Dementias (AD/ADRD) Core plays a central role in achieving the goals of the Massachusetts AI and Technology Center for Connected Care in Aging and Alzheimer's Disease (MAITC) by identifying, selecting, advising, and helping to translate innovative pilot projects that use emerging AI-enhanced technologies to address clinically and societally unmet needs in AD/ADRD. The AD/ADRD Pilot Core will draw on the collective clinical, scientific, and technical expertise within MAITC and the valuable input of our Stakeholder Core and Industry Advisory Board to complete the following specific aims: 1) Solicit and select the most meritorious pilot studies that will develop and test novel AI-enhanced technologies that address clinically important questions in AD/ADRD; 2) Provide mentorship, oversight, and resource supports for pilot project investigators; 3) Assist pilot project investigators in refining their methods and translating their technologies for clinical, industry, and research use. The AD/ADRD Pilot Core Leaders (Drs. Jasmeer Chhatwal and Deborah Blacker) will work MAITC’s other core leaders to coordinate and oversee the pilot project process. The AD/ADRD Pilot Core will solicit pilot projects from the training programs, departments, and centers at universities and research institutions across the nation, drawing on an extensive pool of existing investigators who have expertise in areas such as neurology, psychiatry, geriatrics, technology, computer science, and artificial intelligence. Example topic areas for AD/ADRD pilot projects include: (1) Assessing cognitive impairment-related safety concerns in the patient's home environment; (2) Assessing responses to medical and behavioral interventions and promotion of healthy, potentially-protective behaviors in patients with cognitive impairment; and (3) Informing critical but difficult decisions regarding level-of-care transitions and the need for caregiving assistance inside or outside the home. Once selected, each pilot project leader will be assigned two mentors (at least one of whom will have AD/ADRD clinical expertise) who will provide research guidance and facilitate access to needed resources. The AD/ADRD Pilot Core will work with the other MIATC cores and the AITC Coordinating Center to ensure scientific integrity, rigor and reproducibility, and to facilitate IRB approvals, human subject safety, financial management, and regulatory approvals. The AD/ADRD Pilot Core will help pilot investigators identify critical next steps to move their innovations closer to clinical and research use. To this end, we will provide resources to pilot investigators to refine their technologies, make industry contacts, and develop new grant proposals to accelerate the movement of novel technologies towards the ultimate goal of the AD/ADRD Pilot Core—to improve the care and quality of life for patients and caregivers affected by AD/ADRD.

项目摘要：AD/ADRD 试点核心 阿尔茨海默氏病和相关痴呆症 (AD/ADRD) 核心在实现目标中发挥着核心作用 马萨诸塞州人工智能和技术中心的老龄化和阿尔茨海默病互联护理 (MAITC) 通过识别、选择、建议和帮助转化使用新兴技术的创新试点项目 人工智能增强技术可解决 AD/ADRD 试点中临床和社会未满足的需求。 Core 将利用 MAITC 内集体的临床、科学和技术专业知识以及宝贵的投入 我们的利益相关者核心和行业顾问委员会的成员，以完成以下具体目标：1) 征求和 选择最有价值的试点研究，这些研究将开发和测试新颖的人工智能增强技术，以解决 AD/ADRD 中的临床重要问题 2) 为飞行员提供指导、监督和资源支持 3) 协助试点项目研究人员完善其方法并转化其成果 AD/ADRD 试点核心领导者（Jasmeer 博士） Chhatwal 和 Deborah Blacker）将与 MAITC 的其他核心领导一起协调和监督试点项目 AD/ADRD 试点核心将从培训项目、部门和部门征求试点项目。 全国各地大学和研究机构的中心，利用现有的广泛资源 具有神经病学、精神病学、老年病学、技术、计算机等领域专业知识的研究人员 AD/ADRD 试点项目的示例主题领域包括： (1) 评估 患者家庭环境中与认知障碍相关的安全问题；(2) 评估对患者家庭环境的反应； 医疗和行为干预以及促进患者的健康、潜在保护行为 认知障碍；(3) 为有关护理水平转变和治疗水平的关键但困难的决策提供信息 一旦选定，每个试点项目负责人都将被指定为需要家庭内部或外部的护理援助。 指派两名导师（其中至少一名拥有 AD/ADRD 临床专业知识）来提供研究 AD/ADRD 试点核心将与其他 MIATC 合作。 核心和 AITC 协调中心，以确保科学完整性、严谨性和可重复性，并促进 IRB 批准、人体受试者安全、财务管理和监管批准。 Core 将帮助试点研究人员确定关键的后续步骤，使他们的创新更接近临床和 为此，我们将为试点研究人员提供资源，以完善他们的技术，使之成为可能。 行业联系，并制定新的拨款提案，以加速新技术的发展 AD/ADRD 试点核心的最终目标是改善患者和护理人员的护理和生活质量 受 AD/ADRD 影响。