Development Core-003

开发核心-003

• 批准号: 10660386
• 负责人: MARIA PISU
• 金额: $ 33.89万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-15 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10660386
• 关键词: Address; Alabama; Area; Cancer Burden; Cancer Center; Cancer Control; Cancer Control Research; Cancer Survivor; Caring; Censuses; Collaborations; Communities; Data; Data Analyses; Development; Eligibility Determination; Ensure; Environment; Evaluation; Food Access; Funding; Goals; Health; Health Services Accessibility; Human Resources; Inequity; Institution; Institutional Review Boards; Intervention; Life; Literature; Malignant Neoplasms; Methodology; Mission; National Cancer Advisory Board; National Cancer Institute; Outcome; Peer Review; Phase; Pilot Projects; Postdoctoral Fellow; Poverty; Poverty Areas; Prevention; Process; Research; Research Methodology; Research Personnel; Research Project Grants; Resources; Risk Factors; Rural; Training; Transportation; Universities; University of Alabama at Birmingham Cancer Center; cancer health disparity; career; efficacious intervention; experience; falls; graduate student; improved; member; programs; social; social health determinants; survivorship; synergism; therapy development

DEVELOPMENTAL CORE ABSTRACT The Developmental Core (DC) supports the mission of the University of Alabama at Birmingham (UAB)'s Center for Cancer Control in Persistent Poverty Areas (C3P2) to reduce the burden of cancer and cancer disparities in Persistent Poverty (PP) areas by expanding research and research capacity through implementation and evaluation of multilevel interventions to improve cancer outcomes across the cancer control continuum from prevention to survivorship. The DC expands research in cancer control in (PP) areas of Alabama by developing a research program that builds on the overarching research framework and the proposed research projects. This goal will be achieved by identifying and developing pilot projects in synergy with the C3P2 Community Advisory board (CAB) and the National Cancer Institute (NCI)'s Persistent Poverty Initiative Network (PPIN). The DC will bring together C3P2 investigators, including trainees from the Career Enhancement Core (CEC) and CAB members in a process to identify, select, and prioritize the most relevant and feasible pilot projects. Participation in cross-PPIN centers' collaborative projects will also be considered in this process. With this plan, the DC ensures that pilot projects address the needs and context of PP census tracts and fall within the themes of C3P2 and within the larger goals of the PPIN. Potential pilot projects will build on the current projects that examine the impact of changes in the Living Environment and the adaptation of efficacious interventions to improve cancer outcomes in PP areas, and may investigate multi-level interventions to address needs such as low food access and lack of transportation, as well as specific needs to improve cancer survivors' health. The DC also support the C3P2 mission of expanding research capacity in PP areas by providing research experience opportunities to CEC trainees and other investigators not affiliated with the center, and requiring pilot projects have at least one early career investigator as PI or investigator. All projects will be peer-reviewed to ensure scientific rigor and integrity. The DC will have at least two active projects in each funded year. Lastly, the DC will support the development and implementation of the pilot projects by coordinating the use of resources from the Research and Methods Core (RMC) and the Administrative Core (AC), supporting investigators with IRB applications, training, identifying personnel as needed, and evaluating progress. Thus, the DC is well poised to successfully support the C3P2 and contribute to the goals of the PPIN.

发展核心摘要 发展核心（DC）支持阿拉巴马大学伯明翰（UAB）的任务 持续贫困地区（C3P2）中癌症控制中心（C3P2）减轻癌症的负担 通过扩大研究和研究能力，持续贫困（PP）地区的差异 实施和评估多层干预措施以改善癌症的癌症结果 控制从预防到生存的连续体。 DC扩大了（PP）地区癌症控制的研究 通过制定基于总体研究框架和 拟议的研究项目。该目标将通过确定和开发协同作用中的试点项目来实现 与C3P2社区顾问委员会（CAB）和国家癌症研究所（NCI）的持续贫困 倡议网络（PPIN）。 DC将汇集C3P2调查人员，包括职业生涯的受训者 增强核心（CEC）和CAB会员在一个过程中，以识别，选择和确定最相关的优先级 和可行的试点项目。参与跨彭彭中心的协作项目也将在 这个过程。通过此计划，DC确保飞行员项目满足PP人口普查的需求和背景 区域并属于C3P2的主题以及PPIN的较大目标。潜在的飞行员项目将 建立在当前研究生活环境变化和适应性影响的项目的基础上 有效的干预措施以改善PP地区的癌症结果，并可能研究多层次 解决需求的干预措施，例如食物降低和缺乏运输以及特定需求 改善癌症幸存者的健康。 DC还支持C3P2的使命，以扩大研究能力 PP领域通过为CEC受训者和其他未关联的研究人员提供研究经验机会 与该中心一起，并且需要试点项目至少有一名早期职业调查员作为PI或调查员。全部 项目将进行同行评审，以确保科学严格和完整性。 DC至少有两个活动 每个资助的年度项目。最后，DC将支持飞行员的开发和实施 通过协调从研究和方法核心（RMC）和 行政核心（AC），支持IRB应用程序的调查员，培训，将人员识别为 需要，并评估进度。因此，DC已很好地准备成功支持C3P2并做出贡献 达到PPIN的目标。