METEOR Administrative Core

METEOR 管理核心

• 批准号: 10715020
• 负责人: Clifford Grant Robinson
• 金额: $ 14.34万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10715020
• 关键词: Adoption; Awareness; Basic Science; Biological; Clinical Sciences; Collaborations; Communication; Communication Tools; Data; Development; Ensure; Environment; Improve Access; Malignant neoplasm of cervix uteri; Malignant neoplasm of pancreas; Modeling; Molecular; Monitor; Pathway interactions; Pilot Projects; Process; Radiation therapy; Research Project Grants; Resource Sharing; Resources; Science; Specimen; Structure; Technology; Training; Translations; Universities; University resources; Washington; data management; digital; early phase clinical trial; improved; industry partner; meetings; multidisciplinary; response; success; synergism; tool; tumor; tumor microenvironment

ADMINISTRATIVE CORE SUMMARY Critical to the success of the Washington University (WU) ROBIN “MicroEnvironment Tumor Effects Of Radiotherapy” (METEOR) Center is a structured approach to overall integration and coordination of Center components and strategies while simultaneously ensuring synergy within the overall NCI ROBIN network. The Administrative Core (Admin Core) will tie together the (1) Molecular Characterization Trial (“Comprehensive Radiotherapy Assessment TRial” (METEOR-CRATR)), (2) Research Projects (Project 1 – Cervical cancer (P1- Cervix), Project 2 – Pancreas cancer (P2-Panc)), (3) Shared Resource Cores (SRCs) for omics and data management (“BioLogical Specimen Translation” (METEOR-BLST), “Data Synthesis and Transfer” (METEOR- DST)), and (4) Cross-Training Core (“Integrated Training Environment” (METEORITE)). The Admin Core will also be responsible for management of key initiatives critical to enable short- and long-term success of the METEOR Center and the core tenants of the ROBIN Network. The Admin Core will integrate METEOR Center components through the Admin Core to optimize communication and synergy through a modified hub-and- spoke model with regimented meetings and centrally managed digital collaboration tools and enable a structured approach to iteration and refinement of METEOR Center activities through routine engagement with leaders during meetings. The Admin Core will also operationalize the trans-ROBIN pilot project process and create ongoing opportunities to expand the impact of discovery within the Center through development of trials and technology, and expansion of an evolving multi-disciplinary workforce through regular engagement with WU resources committed to technology and discovery, close integration with METEORITE, and improving awareness within and outside the Network.

行政核心概要 华盛顿大学 (WU) ROBIN“微环境肿瘤效应”的成功至关重要 放射治疗”（METEOR）中心是一个结构化的方法，对中心进行整体整合和协调 组件和策略，同时确保整个 NCI ROBIN 网络内的协同作用。 管理核心（Admin Core）将把（1）分子表征试验（“综合 放射治疗评估试验”（METEOR-CRATR）），（2）研究项目（项目 1 – 宫颈癌（P1- Cervix)，项目 2 – 胰腺癌 (P2-Panc))，(3) 用于组学和数据的共享资源核心 (SRC) 管理（“生物样本翻译”（METEOR-BLST）、“数据合成和传输”（METEOR- (DST))，以及 (4) 交叉培训核心（“集成培训环境”(METEORITE)）。 还负责管理对实现短期和长期成功至关重要的关键举措 METEOR 中心和 ROBIN 网络的核心租户将整合 METEOR 中心。 通过管理核心组件，通过修改后的集线器和-来优化通信和协同作用 具有严格会议和集中管理的数字协作工具的轮辐模型，并支持 通过日常参与来迭代和完善 METEOR 中心活动的结构化方法 管理核心还将在会议期间实施跨 ROBIN 试点项目流程和 通过开展试验创造持续的机会，扩大中心内发现的影响 和技术，并通过定期参与来扩大不断发展的多学科劳动力队伍 WU资源致力于技术和发现，与METEORITE紧密结合，不断完善 网络内外的意识。