Fostering Ethical Neurotechnology Academia-Industry Partnerships: A Stakeholder Engagement and Toolkit Development Project

促进道德神经技术学术界与工业界的伙伴关系：利益相关者参与和工具包开发项目

• 批准号: 10655632
• 负责人: Tristan McIntosh
• 金额: $ 34.99万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10655632
• 关键词: Academia; Address; Adopted; Adoption; Area; BRAIN initiative; Behavior; Brain; Brain Diseases; Case Study; Clinical; Collaborations; Conflict of Interest; Consensus; Data; Development; Devices; Education; Effectiveness; Entrepreneurship; Ethical Issues; Ethicists; Ethics; Evaluation; Fostering; Funding; Goals; Health; Implant; Individual; Industry; Interview; Marketing; Mediation; Mission; Monitor; Online Systems; Patients; Perception; Play; Policies; Privatization; Process; Recommendation; Reporting; Research; Research Contracts; Research Personnel; Resources; Risk Factors; Role; Series; Shapes; Surveys; Technology Transfer; Translation Process; Universities; clinical practice; cognitive interview; commercialization; data sharing; design; financial incentive; health data; industry partner; innovation; innovative neurotechnologies; member; neurotechnology; open data; outreach; prevent; recruit; risk mitigation; stakeholder perspectives; transmission process; webinar

Project Summary Neurotechnologies used to treat brain disorders and diseases can drastically change brain function and behavior, monitor brain activity, and collect and transmit personal health data. Industry-academia (IA) partnerships play a critical role in bringing neurotechnologies to market for public benefit. However, there are significant ethical issues that emerge from these partnerships, especially given the unique capacities of neurotechnologies. If these ethical challenges are not handled appropriately, scientific integrity can be undermined and the objectivity in the design, development, and commercialization of neurotechnologies can be jeopardized. This project addresses a gap in our current understanding of ethical complexities in industry-academia (IA) partnerships within the neurotechnology enterprise by engaging relevant neurotechnology stakeholders (e.g., industry, researchers, ethicists, university officials, patients) to identify promising and practical solutions for addressing these ethical complexities. This project builds logically across three aims that culminate in the development, dissemination, and evaluation of a toolkit that includes stakeholder-informed guidance for ethically and responsibly navigating IA neurotechnology partnerships. Aim 1 will use in-depth interviews with neurotechnology stakeholders to identify risk factors and ethical challenges for IA partnerships, including in the design, conduct, reporting, and application of neurotechnology research. Aim 2 will involve a Delphi consensus panel of neurotechnology stakeholders to establish best practices and solutions for mitigating risk and addressing ethical issues that emerge from IA partnerships. Aim 3 will include developing, disseminating, and evaluating a toolkit that provides guidance and resources for neurotechnology stakeholders to help them ethically and responsibly navigate neurotechnology IA partnerships. We will recommend adoption of specific solutions for each stakeholder group. This is the first project to systematically and simultaneously engage diverse neurotechnology stakeholders to develop practical and actionable guidance for ethical and responsible IA neurotechnology partnerships. We will develop the first publicly accessible stakeholder-informed toolkit that can be adapted to current and forthcoming neurotechnologies resulting from IA partnerships. Taken together, this project will have considerable impact on the conduct of neurotechnology research by identifying practical solutions for balancing scientific values with fiduciary goals.

项目概要 用于治疗大脑紊乱和疾病的神经技术可以极大地改变大脑功能和行为， 监测大脑活动，收集和传输个人健康数据。产学界 (IA) 合作伙伴关系发挥着重要作用 在将神经技术推向市场以造福公众方面发挥着关键作用。然而，存在重大伦理问题 这些伙伴关系中出现的问题，特别是考虑到神经技术的独特能力。如果这些 伦理挑战得不到适当处理，科学诚信可能会受到损害，研究的客观性也可能受到损害。 神经技术的设计、开发和商业化可能会受到损害。 该项目解决了我们目前对工业学术界 (IA) 道德复杂性理解的差距 通过让相关的神经技术利益相关者（例如， 行业、研究人员、伦理学家、大学官员、患者），以确定有前途且实用的解决方案 解决这些道德复杂性。该项目逻辑上跨越三个目标，最终实现 开发、传播和评估工具包，其中包括利益相关者知情的道德指导 并负责任地引导 IA 神经技术合作伙伴关系。 目标 1 将与神经技术利益相关者进行深入访谈，以确定风险因素和道德 IA 合作伙伴面临的挑战，包括神经技术的设计、实施、报告和应用 研究。目标 2 将由神经技术利益相关者组成的德尔福共识小组参与，以建立最佳的 降低风险和解决 IA 合作伙伴关系中出现的道德问题的实践和解决方案。目的 3 将包括开发、传播和评估一个工具包，为 神经技术利益相关者帮助他们以道德和负责任的方式引导神经技术 IA 合作伙伴关系。 我们将建议针对每个利益相关者群体采用特定的解决方案。 这是第一个系统地、同时地让不同的神经技术利益相关者参与的项目 为道德和负责任的 IA 神经技术合作伙伴关系制定实用且可操作的指导。我们将 开发第一个可公开访问的、利益相关者知情的工具包，该工具包可以适应当前和即将到来的情况 IA 合作伙伴关系产生的神经技术。综合来看，该项目将产生相当大的影响 通过确定平衡科学价值与实用价值的实用解决方案来进行神经技术研究 信托目标。