Augmented Reality as an Adjunct to Quitline Counseling for Smoking Cessation

增强现实作为戒烟热线咨询的辅助手段

• 批准号: 10655290
• 负责人: Christine Vinci
• 金额: $ 74.39万
• 依托单位: H. LEE MOFFITT CANCER CTR & RES INST
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10655290
• 关键词: Abstinence; Accounting; Adjuvant; Adoption; Animals; Augmented Reality; Behavioral; Biochemical; Cellular Phone; Cessation of life; Cigarette; Clinic; Clinical; Computer software; Cost Analysis; Cost Effectiveness Analysis; Counseling; Cues; Dependence; Dissemination and Implementation; Elements; Emerging Technologies; Enrollment; Environment; Evaluation; Exposure to; Extinction; Florida; Funding; Future; Goals; Grant; Hour; Human; Hybrids; Individual; Intervention; Interview; Laboratories; Mental Health; Monitor; Morbidity - disease rate; Nicotine Dependence; Outcome; Participant; Patient Recruitments; Patient Self-Report; Pharmacotherapy; Prediction of Response to Therapy; Procedures; Randomized; Research; Risk Reduction; Services; Smoke; Smoker; Smoking; Smoking Cessation Intervention; Smoking Status; Stimulus; Substance Use Disorder; Tablets; Technology; Testing; Tobacco; Tobacco Dependence; United States; Update; Work; arm; cigarette smoking; conditioning; cost; craving; cue reactivity; design; diaries; digital; efficacy evaluation; efficacy testing; experimental study; future implementation; implementation questions; improved; in vivo; incremental cost-effectiveness; indexing; innovation; interest; mHealth; mobile computing; mortality; nicotine replacement; novel; primary outcome; programs; public health priorities; quitline; real world application; recruit; remote administration; response; satisfaction; sex; smartphone application; smoking abstinence; smoking cessation; smoking relapse; standard of care; text messaging intervention; therapy development; tobacco abstinence; tobacco-free; tool; trait; treatment arm; treatment effect; treatment services; treatment strategy; user-friendly; virtual

PROJECT SUMMARY/ABSTRACT Cigarette smoking remains the leading preventable cause of morbidity and mortality in the United States. Developing effective cessation interventions remains a public health priority, and mHealth offers the opportunity to reduce barriers to dissemination and implementation of cessation treatment. This project will test the emerging technology of augmented reality (AR) to enhance smoking cessation among individuals who contact the Tobacco Free Florida quitline for treatment services. AR inserts virtual objects into the real-world environment as viewed on a screen (e.g., smartphone). Cue-exposure treatments have demonstrated efficacy for decreasing tobacco craving in the laboratory, but these effects do not appear to generalize well beyond the extinction setting. This post-extinction “renewal effect” has been demonstrated in both animal and human studies. With the emergence of AR technology, it is now possible to conduct extinction trials across multiple environments throughout smokers’ own real-world smoking settings. The potential to extend the effects of cue- exposure to naturalistic settings offers the opportunity for an innovative and scalable cessation treatment that can be administered remotely. With funding from an R34 treatment development grant, the research team has already developed an app with the basic AR platform. Importantly, we have tested the app in controlled experiments and found that the AR stimuli satisfied the key criterion for extinction cues in that they: (a) elicited substantial cue-reactivity, comparable to in vivo cues and that (b) repeated exposure to the cues reduced craving (i.e., extinction). The primary goal of the proposed project is to extend this initial work by adapting the app for clinical use, with the objective of testing the efficacy of AR when combined with quitline treatment, while also considering key questions relevant to future implementation. Aim 1 will expand the app to be an engaging and user-friendly treatment tool for smokers, and to coordinate all referral procedures between the study team and the Tobacco Free Florida quitline. Aim 2 will recruit participants from the Tobacco Free Florida quitline and randomize individuals either to receive quitline services only or receive quitline services plus the AR app. The primary outcome is biochemically-confirmed tobacco abstinence at 6 months post-enrollment. Aim 3 will evaluate treatment implementation questions to guide future quitline adoption. If the AR app proves to be efficacious, it will be ready for dissemination and implementation through quitlines as well as other smoking cessation programs (e.g., traditional cessation counseling, text messaging interventions, other mobile cessation apps). This work has the potential to inform a range of existing treatments not only for tobacco dependence, but also for other substance use disorders and mental health conditions that are maintained by principles of conditioning.

项目摘要/摘要 吸烟仍然是美国病态和死亡率的主要预防原因。 发展有效的戒烟仍然是公共卫生的先验 减少障碍物的机会和实施情况。 增强现实（AR）的新兴技术是为了增强戒烟的个人 联系烟草免费的佛罗里达戒烟线以获取治疗服务。 在屏幕上查看的象征（例如，智能手机）表现出疗效 为了减少实验室中的烟草渴望，但这种影响似乎并没有概括 灭绝设置。 随着AR技术的出现，可以进行研究。 吸烟者自己的现实吸烟环境中的环境有可能扩大提示的影响。 接触自然主义环境提供了对戒烟治疗的开放性， 可以通过R34治疗开发资助的资金来远程管理 已经开发了一个具有基本AR平台的应用程序。我们已经通过受控测试了该应用程序 经过经验并找到了灭绝线索的关键标准的AR刺激性，这是：（a）引起 实质性提示反应性，可与体内提示相当，并且（b）反复接触提示已减少 渴望（即灭绝）项目的主要目标是通过适应您 临床使用的应用程序，目的是测试与Quitline治疗结合使用AR的功效，而 还考虑与未来实施有关的关键问题。 和用户友好的吸烟工具，并协调研究团队之间的所有推荐程序 烟草免费的烟草2。 随机使个人仅接收Quitline服务，或者接收Quitline服务以及ARPP 主要结果是在注册后6个月的生化确认的烟草禁欲 评估治疗实施问题，以指导未来的Quitline采用。 有效，它将准备好通过戒烟线以及其他吸烟来传播和实施 戒烟计划（例如，传统戒烟咨询，文本消息干预，其他手机 停止应用程序）。 依赖性，也适用于其他药物使用障碍健康状况 条件原则。