Augmented Reality as an Adjunct to Quitline Counseling for Smoking Cessation

增强现实作为戒烟热线咨询的辅助手段

• 批准号: 10655290
• 负责人: Christine Vinci
• 金额: $ 74.39万
• 依托单位: H. LEE MOFFITT CANCER CTR & RES INST
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10655290
• 关键词: Abstinence; Accounting; Adjuvant; Adoption; Animals; Augmented Reality; Behavioral; Biochemical; Cellular Phone; Cessation of life; Cigarette; Clinic; Clinical; Computer software; Cost Analysis; Cost Effectiveness Analysis; Counseling; Cues; Dependence; Dissemination and Implementation; Elements; Emerging Technologies; Enrollment; Environment; Evaluation; Exposure to; Extinction; Florida; Funding; Future; Goals; Grant; Hour; Human; Hybrids; Individual; Intervention; Interview; Laboratories; Mental Health; Monitor; Morbidity - disease rate; Nicotine Dependence; Outcome; Participant; Patient Recruitments; Patient Self-Report; Pharmacotherapy; Prediction of Response to Therapy; Procedures; Randomized; Research; Risk Reduction; Services; Smoke; Smoker; Smoking; Smoking Cessation Intervention; Smoking Status; Stimulus; Substance Use Disorder; Tablets; Technology; Testing; Tobacco; Tobacco Dependence; United States; Update; Work; arm; cigarette smoking; conditioning; cost; craving; cue reactivity; design; diaries; digital; efficacy evaluation; efficacy testing; experimental study; future implementation; implementation questions; improved; in vivo; incremental cost-effectiveness; indexing; innovation; interest; mHealth; mobile computing; mortality; nicotine replacement; novel; primary outcome; programs; public health priorities; quitline; real world application; recruit; remote administration; response; satisfaction; sex; smartphone application; smoking abstinence; smoking cessation; smoking relapse; standard of care; text messaging intervention; therapy development; tobacco abstinence; tobacco-free; tool; trait; treatment arm; treatment effect; treatment services; treatment strategy; user-friendly; virtual

PROJECT SUMMARY/ABSTRACT Cigarette smoking remains the leading preventable cause of morbidity and mortality in the United States. Developing effective cessation interventions remains a public health priority, and mHealth offers the opportunity to reduce barriers to dissemination and implementation of cessation treatment. This project will test the emerging technology of augmented reality (AR) to enhance smoking cessation among individuals who contact the Tobacco Free Florida quitline for treatment services. AR inserts virtual objects into the real-world environment as viewed on a screen (e.g., smartphone). Cue-exposure treatments have demonstrated efficacy for decreasing tobacco craving in the laboratory, but these effects do not appear to generalize well beyond the extinction setting. This post-extinction “renewal effect” has been demonstrated in both animal and human studies. With the emergence of AR technology, it is now possible to conduct extinction trials across multiple environments throughout smokers’ own real-world smoking settings. The potential to extend the effects of cue- exposure to naturalistic settings offers the opportunity for an innovative and scalable cessation treatment that can be administered remotely. With funding from an R34 treatment development grant, the research team has already developed an app with the basic AR platform. Importantly, we have tested the app in controlled experiments and found that the AR stimuli satisfied the key criterion for extinction cues in that they: (a) elicited substantial cue-reactivity, comparable to in vivo cues and that (b) repeated exposure to the cues reduced craving (i.e., extinction). The primary goal of the proposed project is to extend this initial work by adapting the app for clinical use, with the objective of testing the efficacy of AR when combined with quitline treatment, while also considering key questions relevant to future implementation. Aim 1 will expand the app to be an engaging and user-friendly treatment tool for smokers, and to coordinate all referral procedures between the study team and the Tobacco Free Florida quitline. Aim 2 will recruit participants from the Tobacco Free Florida quitline and randomize individuals either to receive quitline services only or receive quitline services plus the AR app. The primary outcome is biochemically-confirmed tobacco abstinence at 6 months post-enrollment. Aim 3 will evaluate treatment implementation questions to guide future quitline adoption. If the AR app proves to be efficacious, it will be ready for dissemination and implementation through quitlines as well as other smoking cessation programs (e.g., traditional cessation counseling, text messaging interventions, other mobile cessation apps). This work has the potential to inform a range of existing treatments not only for tobacco dependence, but also for other substance use disorders and mental health conditions that are maintained by principles of conditioning.

项目摘要/摘要 吸烟仍然是美国发病率和死亡率的主要预防原因。 制定有效的停止干预措施仍然是公共卫生的重点，MHealth提供了 减少传播和实施戒烟治疗的机会。这个项目将测试 增强现实（AR）的新兴技术是为了增强戒烟的个人 请联系烟草免费的佛罗里达州戒烟线以进行治疗服务。 AR将虚拟对象插入现实世界中 如在屏幕上查看的环境（例如智能手机）。提示暴露治疗表明效率 为了减少实验室中的烟草渴望，但这些影响似乎并没有概括 扩展设置。在动物和人类中都证明了这种爆发后的“更新效应” 研究。随着AR技术的出现，现在可以进行跨多个的扩展试验 吸烟者自己的现实吸烟环境中的环境。扩展提示的影响的潜力 暴露于自然主义环境为创新且可扩展的戒烟处理提供了机会 可以远程管理。在R34治疗开发资助的资金中，研究小组拥有 已经开发了一个具有基本AR平台的应用程序。重要的是，我们已经通过受控测试了该应用 实验并发现AR刺激满足了扩展线索的关键标准：（a）引起 实质性提示反应性，可与体内提示相当，并且（b）反复接触提示已减少 渴望（即扩展）。拟议项目的主要目标是通过适应 临床使用的应用程序，目的是测试与Quitline治疗结合使用AR的效率，而 还考虑与未来实施有关的关键问题。 AIM 1将扩展应用程序成为一种引人入胜的 和吸烟者的用户友好治疗工具，并协调研究团队之间的所有推荐程序 和烟草免费的佛罗里达戒烟线。 AIM 2将从烟草免费招募参与者， 随机对个人进行随机，要么仅接收Quitline服务，要么接收Quitline服务以及AR应用程序。这 主要结果是在注册后6个月的生化确认的烟草禁欲。目标3意志 评估治疗实施问题，以指导未来的Quitline采用。如果AR应用被证明是 它将准备通过戒烟和其他吸烟进行传播和实施 戒烟计划（例如，传统戒烟咨询，文本消息干预，其他手机 停止应用程序）。这项工作有可能告知一系列现有治疗方法 依赖性，以及其他物质使用障碍和心理健康状况的依赖 条件原则。