Research Services Core

研究服务核心

基本信息

批准号：
10472667
负责人：
ALAN E JONES
金额：
$ 54.5万
依托单位：
UNIVERSITY OF MISSISSIPPI MED CTR
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-08-18 至 2026-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10472667
关键词：
Address Adult African American population Alabama Area Atherosclerosis Risk in Communities Award Beds Behavior Therapy Bioethics Biometry Budgets Cardiometabolic Disease Clinic Clinical Clinical Investigator Clinical Research Clinical Sciences Clinical Services Clinical Trials Clinical Trials Data Monitoring Committees Clinical Trials Unit Cohort Studies Collaborations Communities Community Outreach Consult Data Development Economically Deprived Population Emergency Medicine Enrollment Epidemiology Extramural Activities Funding Goals Growth Health Health Sciences Hospitals Industry Informed Consent Infrastructure Institutes Institution Institutional Review Boards Investigation Jackson Heart Study Link Longitudinal Studies Louisiana Low Income Population Mississippi NCI Scholars Program Obesity Outcome Participant Pathogenesis Patient Recruitments Patients Phase Pilot Projects Population Positioning Attribute Procedures Process Protocols documentation Research Research Design Research Ethics Research Personnel Research Project Grants Research Project Summaries Research Training Resources Risk Rural Rural Health Services Standardization Stream Tissues Training Translational Research United States Health Resources and Services Administration Universities Work biobank career clinical center cohort community based participatory research community engagement data warehouse design electronic consent epidemiology study ethnic health disparity experience health data health disparity implementation facilitation implementation research implementation science improved participant retention population health professor programs racial and ethnic recruit research and development research study responsible research conduct rural area sample collection sound success telehealth

项目摘要

PROJECT SUMMARY-RESEARCH SERVICES CORE. The goal of the Mississippi Center for Clinical and Translational Research (MCCTR) Research Services Core (RSC) is to train and assist investigators in research development and implementation including regulatory management, responsible conduct of research, effective recruitment and retention, and research compliance. The RSC will provide a broad range of clinical, epidemiologic, and population health expertise to investigators from the MCCTR Clinical and Translational Research Scholars (CTRS) Program and Pilot Projects Program (PPP) to facilitate growth in clinical and translational (C/T) and population health research with an emphasis on: racial/ethnic health disparities, rural health, and telehealth. To facilitate implementation of C/T research to improve the lives of Mississippians, the RSC will develop a new Telehealth subcore to reach rural areas of the state, which have high rates of cardiometabolic diseases and worse health outcomes. In collaboration with the Community Engagement and Outreach (CEO) Core, the RSC will also leverage new state networks including the Mississippi State Department of Health and Mississippi State Extension Services to expand the reach of these important clinical programs. During MCCTR Phase II, the RSC will expand use of electronic health data by partner institutions through greater use of the UMMC Research Data Warehouse and Patient Cohort Explorer, which will allow investigators to use “real world” data to explore a variety of health indicators and outcomes. The RSC will also facilitate broader early career investigator involvement in large epidemiologic studies including the Jackson Heart Study, the Atherosclerosis Risk in Communities (ARIC) Study, and the Risk Underlying Rural Areas Longitudinal (RURAL) Study through creation of a new Cohort Study Navigator position. The RSC will work closely with all of the cores but early interactions with the Biostatistics, Epidemiology, and Research Design (BERD) Core with each MCCTR investigator will optimize chances of successful project design and completion. UMMC will serve as the “hub” for clinical trials, and the RSC will expand use of the UMMC Clinical Research and Trials Unit through the RSC Clinical Research Coordinators. The RSC will streamline the clinical trial process for MCCTR investigators and assist with participant recruitment and retention of a diverse participant population by the partner institutions. The RSC will also help expand collaborations between the MCCTR partner institutions as well as other CTRs/CTSAs including the Mayo Clinic Center for Clinical and Translational Science (CCaTS), the University of Alabama Birmingham Center for Clinical and Translational Science (UAB CCTS), the Louisiana Clinical and Translational Science (LACaTS), and the Northwestern University Clinical and Translational Sciences Institute (NUCATS). These collaborative networks will provide unique opportunities for larger scale investigations of health disparities, rural health, and telehealth.

项目摘要-研究服务核心。密西西比临床和研究中心的目标。转化研究 (MCCTR) 研究服务核心 (RSC) 旨在培训和协助研究人员进行研究制定和实施，包括监管管理、负责任的研究行为、有效的 RSC 将提供广泛的临床、招募和保留以及研究合规性。流行病学和人口健康专家以及 MCCTR 临床和转化研究人员研究学者 (CTRS) 计划和试点项目计划 (PPP)，以促进临床和转化（C/T）和人口健康研究，重点是：种族/民族健康差异、农村为了促进 C/T 研究的实施，以改善密西西比人的生活， RSC 将开发一个新的远程医疗子核心，以覆盖该州农村地区，这些地区的远程医疗比率很高与社区参与合作，预防心脏代谢疾病和更糟糕的健康结果。外展（首席执行官）核心，RSC 还将利用新的州网络，包括密西西比州国务院卫生局和密西西比州推广服务部扩大这些重要临床计划的覆盖范围。在 MCCTR 第二阶段期间，RSC 将通过更广泛的方式扩大合作机构对电子健康数据的使用使用 UMMC 研究数据仓库和患者队列浏览器，这将允许研究人员使用 RSC 还将利用“真实世界”数据来探索各种健康指标和结果，从而促进更广泛的早期研究。职业研究者参与大型流行病学研究，包括杰克逊心脏研究、社区动脉粥样硬化风险 (ARIC) 研究和农村地区潜在风险纵向 (RURAL) 通过创建新的队列研究导航员职位进行研究 RSC 将与所有核心人员密切合作。但与每个 MCCTR 的生物统计学、流行病学和研究设计 (BERD) 核心的早期互动研究者将优化项目设计和完成的成功机会，UMMC 将作为“中心”。临床试验，RSC 将通过 RSC 扩大 UMMC 临床研究和试验单位的使用临床研究协调员将简化 MCCTR 研究者和临床试验流程。协助合作伙伴机构招募参与者并保留多样化的参与者群体。 RSC 还将帮助扩大 MCCTR 合作机构以及其他机构之间的合作 CTR/CTSA 包括梅奥诊所临床和转化科学中心 (CCaTS)、阿拉巴马州伯明翰临床和转化科学中心 (UAB CCTS)、路易斯安那州临床和转化科学中心转化科学 (LACaTS) 和西北大学临床与转化科学研究所（NUCATS）。这些协作网络将为更大规模的研究提供独特的机会。健康差距、农村卫生和远程医疗。