Africa Center for Biostatistical Excellence: Expanding biostatistical leadership for HIV/AIDS and TB Research

非洲生物统计卓越中心：扩大生物统计对艾滋病毒/艾滋病和结核病研究的领导作用

• 批准号: 10472777
• 负责人: Rhoderick Machekano
• 金额: $ 29.39万
• 依托单位: STELLENBOSCH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-19 至 2027-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10472777
• 关键词: 2019-nCoV; AIDS/HIV problem; Address; Africa; Africa South of the Sahara; Area; Biometry; COVID-19; COVID-19 impact; Caring; Data; Development; Disease; E-learning; Educational Status; Educational process of instructing; Evaluation; Faculty; Future; Grant; HIV; Health; Health Sciences; Healthcare Systems; Infection; Infrastructure; Institution; International; Lead; Leadership; Medicine; Persons; Research; Research Activity; Research Design; Research Methodology; Research Project Grants; Research Training; South Africa; Students; Supervision; Targeted Research; Training; Training Programs; Universities; Virus; academic program; burden of illness; care delivery; data management; low and middle-income countries; novel; programs; response; treatment program

PROJECT SUMMARY LMIC: South Africa Institution: Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town Scientific Area: Biostatistics for HIV/AIDS and TB research design and methodology Africa Center for Biostatistical Excellence: expanding biostatistical leadership for HIV/AIDS and TB research This application is in response to the FOA “Fogarty HIV Research Training Program for Low- and Middle- Income Country Institutions” under the D43 grant mechanism (FOA PAR-19-283) and requests 5 years of support to expand biostatistics leadership for HIV research design and methodology at Stellenbosch University in South Africa. HIV/AIDS and TB remain the highest contributors to the burden of disease in sub-Saharan Africa (SSA). The COVID-19 disease resulting from infection with the novel SARS-CoV-2 virus poses a threat to the fragile healthcare system and infrastructure in SSA. In particular, COVID-19 effects on the delivery of care to people living with HIV/AIDS is likely to reverse gains in care and treatment programs achieved over decades. Data driven solutions and targeted research and evaluations demand complimentary teams of leaders, including biostatisticians. There is a huge deficit of doctoral level biostatisticians in the region. In 2017, we successfully implemented a masters’ level training program in biostatistics for HIV/AIDS research. Despite shortage in local biostatisticians with advanced training, we mobilized international collaborators to assist with teaching and student supervision. For sustainability of our training program, the natural progression is to train local future leaders in biostatistics who will continue the training initiatives and also provide research leadership to address the myriad of health problems in SSA. We propose to continue our efforts to bridge the gap in biostatistics capacity in SSA and develop research leadership at Stellenbosch University and the region at large. The specific objectives of this renewal of the training grant are to: (1) develop biostatistics leadership through a doctoral training program at Stellenbosch University; (2) continue building biostatistics capacity through a Masters’ level academic program and expand our reach using e-learning platforms; (3) consolidate the ACBE as a leader in providing professional development in biostatistics and data management to support HIV/AIDS research projects and programs within the SSA region and lead HIV/AIDS and TB research activities.

项目摘要 LMIC：南非 机构：开普敦Stellenbosch大学医学与健康科学学院 科学领域：艾滋病毒/艾滋病和结核病研究设计与方法论的生物统计学 非洲生物统计学卓越中心：扩大艾滋病毒/艾滋病的生物统计领导 结核病研究 该应用是响应FOA“低和中间的Fogarty HIV研究培训计划 D43赠款机制（FOA PAR-19-283）下的收入国家机构”，要求5年 支持Stellenbosch University的HIV研究设计和方法的生物统计学领导 在南非。 在撒哈拉以南非洲（SSA）中，艾滋病毒/艾滋病和结核病仍然是疾病燃烧的最高贡献者。这 新型SARS-COV-2病毒感染引起的Covid-19疾病对脆弱的威胁构成威胁 SSA中的医疗保健系统和基础设施。特别是，covid-19对向人们提供护理的影响 与艾滋病毒/艾滋病有关的生活可能会扭转数十年来实现的护理和治疗计划。数据 驱动的解决方案和针对性的研究和评估要求领导人的免费团队，包括 生物统计学家。该地区的博士生物统计学家存在很大的缺陷。 在2017年，我们成功地实施了艾滋病毒/艾滋病研究生物统计学的硕士水平培训计划。 尽管当地的生物统计学家缺乏高级培训，但我们动员了国际合作者 协助教学和学生监督。为了使我们的培训计划的可持续性，自然 进步是培训当地未来的领导者的生物统计学，他们将继续培训计划，也是 提供研究领导，以解决SSA的无数健康问题。 我们建议继续努力弥合SSA生物统计学能力的差距，并开发研究 Stellenbosch大学和整个地区的领导。此更新的具体目标 培训补助金是：（1）通过Stellenbosch的博士培训计划发展生物统计学领导 大学; （2）通过大师级的学术计划继续建立生物统计学能力并扩展 我们使用电子学习平台的范围； （3）将ACBE巩固为提供专业的领导者 生物统计学和数据管理中的发展，以支持艾滋病毒/艾滋病研究项目和计划 在SSA地区，铅HIV/AIDS和结核病研究活动。