Pharmacokinetics (PK)

药代动力学（PK）

基本信息

批准号：
10438621
负责人：
DUXIN SUN
金额：
$ 13.88万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-06-01 至 2023-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10438621
关键词：
Adopted Antineoplastic Agents Applications Grants Cancer Center Cancer Center Support Grant Chemicals Clinical Collaborations Consultations Data Development Developmental Therapeutics Program Doctor of Philosophy Drug Kinetics Electrospray Ionization Funding Future Goals Grant Individual Interdisciplinary Study Joints Lead Legal patent Maps Mass Spectrum Analysis Methods Pathway interactions Peer Review Grants Pharmaceutical Preparations Pharmacology Phase Population Productivity Publications Research Research Personnel Resolution Resource Sharing Resources Sampling Science Secure Services Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization System Techniques Technology The Sun Time Tissue Sample Tissue imaging Tissues Training Translations University of Michigan Comprehensive Cancer Center anti-cancer therapeutic anticancer activity anticancer research base cost dosage drug development drug discovery drug market drug metabolism experience imaging biomarker innovation instrument instrumentation liquid chromatography mass spectrometry mass spectrometric imaging member novel operation pharmacokinetics and pharmacodynamics phase II trial phase IV trial pre-clinical programs

项目摘要

PROJECT SUMMARY/ABSTRACT (PHARMACOKINETICS) The Pharmacokinetics (PK) Shared Resource (SR) was founded in 2009 and has been funded by the CCSG since 2012. The goal of the PK SR is to provide high quality, cost- and time-efficient services that propel cancer research forward. It uses one-on-one consultations with University of Michigan Comprehensive Cancer Center (UMCCC) members at the start of projects to stimulate innovative research and to support multidisciplinary collaborations. The SR has successfully grown in capability, services, and staffing in order to keep pace with an expanding user base. Since its inception, the PK SR has been led by Duxin Sun, PhD, a skilled investigator with extensive experience in preclinical and clinical PK and drug development. By working closely with UMCCC leaders and members, Dr. Sun and his team have anticipated the changing needs of UMCCC researchers by adopting state-of-the-art technologies and approaches that accelerate the development of novel anticancer therapeutics arising from member research.

项目摘要/摘要（药代动力学）药代动力学 (PK) 共享资源 (SR) 成立于 2009 年，由 CCSG 资助自 2012 年以来。PK SR 的目标是提供高质量、具有成本效益和时间效率的服务，推动癌症研究向前发展。它与密歇根大学综合癌症中心进行一对一咨询中心 (UMCCC) 成员在项目启动时刺激创新研究并支持多学科合作。 SR 在能力、服务和人员配置方面已成功发展，以便跟上不断扩大的用户群的步伐。自成立以来，PK SR 一直由孙笃新博士领导。熟练的研究者，在临床前和临床 PK 以及药物开发方面拥有丰富的经验。通过工作孙博士和他的团队与UMCCC领导和成员密切合作，预见到了不断变化的需求 UMCCC 研究人员采用最先进的技术和方法来加速成员研究产生的新型抗癌疗法的开发。