Mayo Clinic Research Education Program in Computational Autonomic Neurobiology of Diabetes and Digestive and Kidney Diseases

梅奥诊所糖尿病、消化和肾脏疾病计算自主神经生物学研究教育项目

• 批准号: 10709578
• 负责人: David R. Linden
• 金额: $ 12.96万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-30 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10709578
• 关键词: Address; Biomedical Engineering; Clinic; Clinical; Complex; Computational Science; Computer Analysis; Computers; Computing Methodologies; Data; Data Scientist; Data Set; Development; Diabetes Mellitus; Digestive System Disorders; Disease; Distant; Education; Educational Curriculum; Educational Materials; Educational Models; Ensure; Environment; Faculty; Funding; Future; Generations; Health; Human; Institution; International; Investments; Kidney Diseases; Knowledge; Laboratories; Lead; Learning; Medical; Medicine; Mentors; Methods; Minnesota; Modernization; Neurobiology; Participant; Physicians; Physiological; Physiology; Postdoctoral Fellow; Productivity; Program Evaluation; Research; Research Project Grants; Resources; Schools; Science; Scientist; Training; Training Programs; biomedical scientist; career; complex data; computational platform; computerized tools; design; direct application; education research; experience; graduate student; innovation; large datasets; next generation; open data; patient engagement; programs; recruit; skill acquisition; skills; skills training

Project Summary / Abstract Modern biomedical science and medicine, with large varied and complex datasets, requires a paradigm shift in our educational models to train the next generation of scientists and physicians capable of performing and interpreting computational analyses. Current educational models have created a critical gap of expertise between computational data scientists and disease-oriented physiologists. The Specific Aim of this proposal is to establish an innovative educational model to promote the training of computational skills for immediate and direct application to research experiences and create the next generation of biomedical scientists to lead new discoveries in diabetes, digestive and kidney disease-oriented research. The Mayo Clinic Research Education Program in Computational Autonomic Neurobiology is a unique new program designed to ensure foundational understanding of both computational science and disease-oriented physiology, prior to learning practical skills in computational methods that are directly applied to data from mentored research experiences. Participants in the program, including graduate students, post-doctoral fellows, biomedical engineers, medical residents, and clinical fellows, are recruited widely from existing educational, training and research programs via the international reputations and productivity of the highly invested participating faculty. The program leverages institutional resources for program administration and robust program evaluation to remain adaptive and responsive to the needs of participants. The short-term objectives of the program are to: 1) provide foundational knowledge in physiology and computational science; 2) provide practical skill in the use creation and dissemination of computational workflows; and 3) provide a research environment to enrich skill honing and productivity. The long-term objectives of the program are to: 4) expand the use and access of computational analyses to impact diabetes, digestive and kidney disease-oriented research; and 5) attract and retain diverse scientists that impact the fields of diabetes, digestive and kidney disease- oriented research. By completing the program, we anticipate these scientists will form a bridge between the often distant physiological and computational approaches to understand human health and form a generation of diverse scientists that impact the fields of diabetes, digestive and kidney diseases.

项目概要/摘要 现代生物医学科学和医学拥有大量多样且复杂的数据集，需要 教育模式的范式转变，以培养下一代科学家和医生 能够执行和解释计算分析。目前的教育模式有 在计算数据科学家和疾病导向科学家之间造成了严重的专业知识差距 生理学家。本提案的具体目标是建立创新的教育模式 促进计算技能的培训，以便立即直接应用于研究 经验并培养下一代生物医学科学家来引领新发现 以糖尿病、消化系统和肾脏疾病为导向的研究。梅奥诊所研究教育 计算自主神经生物学项目是一个独特的新项目，旨在确保 在之前对计算科学和疾病导向的生理学有基本的了解 学习直接应用于指导数据的计算方法的实用技能 研究经验。该计划的参与者包括研究生、博士后、 生物医学工程师、住院医师和临床研究员是从现有的人员中广泛招募的 通过国际声誉和生产力开展教育、培训和研究计划 高度投入的参与教师。该计划利用机构资源来开展计划 管理和强有力的计划评估，以保持适应和响应需求 参与者。该计划的短期目标是： 1）提供以下方面的基础知识： 生理学和计算科学； 2）提供使用创建和传播的实用技能 计算工作流程； 3）提供研究环境以丰富技能磨练和 生产率。该计划的长期目标是： 4) 扩大 影响糖尿病、消化系统和肾脏疾病研究的计算分析；和 5) 吸引并留住影响糖尿病、消化系统和肾脏疾病领域的多元化科学家—— 定向研究。通过完成该计划，我们预计这些科学家将搭建一座桥梁 理解人类健康的生理学方法和计算方法通常相距甚远 培养影响糖尿病、消化和肾脏领域的一代多元化科学家 疾病。