Multidisciplinary Training Program in Basic Diabetes Research

基础糖尿病研究多学科培训计划

• 批准号: 9339668
• 负责人: Ormond A MacDougald
• 金额: $ 23.87万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-01 至 2019-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9339668
• 关键词: Diabetes Mellitus; Research; Training Programs; multidisciplinary

DESCRIPTION (provided by applicant): The burden of diabetes and its complications stresses the need for academic research institutions and diabetes researchers to train well-qualified research scientists to develop new avenues for the treatment, prevention and cure of diabetes. The primary goal of this training grant is to train PhD basic scientists for careers in diabetes research using a multidisciplinary and comprehensive learning experience, scientific interactions and mentorship to develop a deep understanding of the molecular aspects of diabetes. This training program is embedded within the rich research environment of the University of Michigan, which includes a highly collegial, and interdisciplinary diabetes research community and excellent core resources for biomedical research. The training program builds on the unique expertise of the group of preceptors in different components of the pathogenesis diabetes and its complications. Training grant preceptors fall into six major interest groups - islt biology, autoimmune diabetes, adipocyte biology, hypothalamic regulation of metabolism, mechanisms of Insulin resistance and metabolic control (liver, adipocyte and muscle groups) and diabetes complications. The program includes training in the individual laboratory but is supplemented by a core curriculum in molecular pathogenesis of diabetes as well as an interdisciplinary and collaborative series of educational project meetings, seminars, activities in grant writing, career advance and research methodologies. This training will provide the necessary tools for transition to independence. This program includes 18 mentors in a highly collaborative environment with stable extramural funding who have appointments in nine separate departments in the School of Medicine and two Divisions within the Department of Internal Medicine. This program will provide a significant complement for the training mission of the Michigan Diabetes Research Center and the Nutrition and Obesity Research Center. The training program will be administered through the Division of Metabolism Endocrinology and Diabetes, and will be overseen by an executive committee comprising the Principal Investigator, one co-director and four members of whom are senior investigators with strong mentoring track records.

描述（由申请人提供）：糖尿病及其并发症的负担强调了学术研究机构和糖尿病研究人员的需求，以培训合格的研究科学家，以开发新的途径，以治疗，预防和治愈糖尿病。这项培训补助金的主要目的是使用多学科和全面的学习经验，科学互动和指导来培训糖尿病研究职业的基础科学家，以深入了解糖尿病的分子方面。该培训计划嵌入了密歇根大学丰富的研究环境中，该大学包括高度合作，跨学科的糖尿病研究界以及生物医学研究的优质核心资源。该培训计划以发病机理糖尿病及其并发症的不同成分中的受体组的独特专业知识为基础。培训赠款培训者分为六个主要利益群体 - ISLT生物学，自身免疫性糖尿病，脂肪细胞生物学，下丘脑代谢的下丘脑调节，胰岛素抵抗和代谢对照机制（肝脏，脂肪细胞和肌肉组）以及糖尿病的并发症。该计划包括在单个实验室进行培训，但补充了糖尿病分子发病机理的核心课程，以及一系列跨学科和协作系列的教育项目会议，研讨会，活动，活动 授予写作，职业进步和研究方法。该培训将为过渡到独立性提供必要的工具。该计划包括在高度协作环境中的18位导师，并具有稳定的校外资金，他们在医学院的九个独立部门和内科部门的两个部门中任命。该计划将为密歇根州糖尿病研究中心和营养与肥胖研究中心的培训任务提供重要补充。该培训计划将通过代谢内分泌学和糖尿病的划分来管理，并将由一个执行委员会监督，该委员会由首席调查员，一名联合导演和四名成员组成，其中四名成员是具有强大指导记录的高级研究人员。