University of Michigan Regional Coordinating Center (RCC) StrokeNet

密歇根大学区域协调中心 (RCC) StrokeNet

基本信息

批准号：
9569076
负责人：
DEVIN L BROWN
金额：
$ 31.2万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-08-15 至 2023-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9569076
关键词：
Accident and Emergency department Adult Agreement Applied Research Area Basic Science Blood Vessels Cause of Death Childhood stroke Clinical Clinical Research Clinical Sciences Clinical Trials Clinical Trials Design Clinical Trials Network Clinical Trials Support Unit Collaborations Conduct Clinical Trials Data Quality Development Emergency Care Emergency Medicine Enrollment Faculty Fellowship Program Foundations Funding Geography Goals Health Home environment Informed Consent Institutes Lead Leadership Mentorship Michigan Mission NCI Scholars Program National Institute of Neurological Disorders and Stroke Neurological emergencies Neurology Patients Phase Phase III Clinical Trials Physician Executives Population Population Heterogeneity Prevention Public Health Schools Recording of previous events Records Recovery Rehabilitation therapy Research Research Infrastructure Research Personnel Research Training Resources Site Speed Stroke Stroke prevention StrokeNet clinical trials System Training Training Programs United States National Institutes of Health Universities Wood material care systems career career development cohesion design disability experience innovation investigator training multidisciplinary patient population pediatric emergency programs protocol development recruit stroke clinical trials stroke intervention stroke patient stroke trials success synergism treatment trial

项目摘要

The purpose of a University of Michigan Regional Coordinating Stroke Center (UM RCC) is to continue to participate fully in the NIH StrokeNet clinical trials network through clinical trial development, enrollment, and implementation, and the training of early stage investigators in stroke research. The University of Michigan has a long track record of clinical science excellence, expertise in clinical stroke management, excellence in creating stroke systems of care, expertise in stroke clinical trial design and implementation, and a proven ability to recruit subjects. The UM RCC includes affiliate spokes in a geographically focused region with which UM has a history of collaboration, and provides access to a large and diverse stroke patient population. UM has tremendous infrastructure for the conduct of clinical trials including a CTSA-funded Michigan Institute for Clinical & Health Research, and Clinical Trial Support Units, both of which directly benefit the UM RCC. Moreover, the Departments of Emergency Medicine and Neurology at UM are fully supportive of the continuation of a UM RCC. The applicants are part of a dedicated multidisciplinary team of investigators who are experienced in stroke clinical trials and enthusiastic to continue working collaboratively on Network trials and offer enrollment to all eligible patients. Also included are world-class experts in stroke basic science who can continue to contribute to the leadership and training within a UM RCC and the overall network. The UM RCC has proposed and will continue to propose trials for conduct in the Network. One UM RCC proposed clinical trial has been approved for funding. The University of Michigan is already home to the NINDS-funded Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) National Clinical Coordinating Center (PI: Barsan) and its prior incarnation, the Neurological Emergencies Treatment Trials (NETT), and thus has tremendous experience with the design and conduct of clinical trials within networks. Equally as important to the successful conduct of clinical trials within a UM RCC, the UM Stroke Program has a proven track record for developing academic clinical researchers in stroke, as this is the primary mission of its fellowship program. Unique resources are available at UM for formal didactic training in clinical research through its nationally recognized School of Public Health and its Clinician Scholars Program. Trainees within a UM RCC also benefit tremendously from the mentorship of a highly integrated multidisciplinary faculty with significant expertise in stroke clinical trials and clinical stroke research. The initial years of the UM RCC have proven its success in clinical trial enrollment, early investigator training, multi-level network engagement, and clinical trial proposal development.

密歇根大学地区卒中协调中心 (UM RCC) 的目的是继续通过临床试验开发、注册和临床试验充分参与 NIH StrokeNet 临床试验网络实施以及中风研究早期研究人员的培训。密歇根大学有长期临床科学卓越记录、临床中风管理专业知识、卓越的创建中风护理系统、中风临床试验设计和实施方面的专业知识以及经过验证的招募受试者的能力。 UM RCC 包括在地理集中区域的附属辐条，其中密歇根大学有着合作的历史，并为大量不同的中风患者群体提供了接触机会。密歇根大学拥有用于进行临床试验的庞大基础设施，包括 CTSA 资助的密歇根研究所临床与健康研究以及临床试验支持单位，这两个单位都直接使 UM RCC 受益。此外，UM 急诊医学科和神经病学系全力支持 UM RCC 的延续。申请人是专门的多学科研究团队的一部分，他们在中风临床试验方面经验丰富，并热衷于继续在网络试验方面进行合作并向所有符合条件的患者提供登记。还包括世界一流的中风基础科学专家，他们可以继续为 UM RCC 和整个网络的领导和培训做出贡献。密西根大学 RCC 已提议并将继续提议在网络中进行试验。拟建一所 UM RCC 临床试验已获得资助。密歇根大学已经是 NINDS 资助的项目的所在地创新紧急护理临床试验网络 (SIREN) 国家临床协调中心的策略（PI：Barsan）及其前身，神经紧急情况治疗试验（NETT），因此具有在网络内设计和进行临床试验方面拥有丰富的经验。同样重要的是 UM 中风项目在 UM RCC 内成功进行了临床试验，在以下方面拥有良好的记录：培养中风学术临床研究人员，因为这是其奖学金计划的主要任务。 UM 拥有独特的资源，可通过其全国性的临床研究正式教学培训认可的公共卫生学院及其临床医生学者计划。 UM RCC 内的学员也受益这很大程度上得益于高度综合的多学科教师的指导，他们在中风临床试验和临床中风研究方面拥有丰富的专业知识。 UM RCC 的最初几年已经证明了其成功临床试验注册、早期研究者培训、多层次网络参与和临床试验提案制定。

项目成果

期刊论文数量（4）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Sleep disorders and the risk of stroke.

DOI：
10.1080/14737175.2018.1489239
发表时间：
2018-07
期刊：
Expert review of neurotherapeutics
影响因子：
4.3
作者：
McDermott M;Brown DL;Chervin RD
通讯作者：
Chervin RD

Reach Out Churches: A Community-Based Participatory Research Pilot Trial to Assess the Feasibility of a Mobile Health Technology Intervention to Reduce Blood Pressure Among African Americans.

DOI：
10.1177/1524839917710893
发表时间：
2018-07
期刊：
Health promotion practice
影响因子：
1.9
作者：
Skolarus LE;Cowdery J;Dome M;Bailey S;Baek J;Byrd JB;Hartley SE;Valley SC;Saberi S;Wheeler NC;McDermott M;Hughes R;Shanmugasundaram K;Morgenstern LB;Brown DL
通讯作者：
Brown DL