MassHEAL - Reducing overdose deaths by 40% (2019-2023)

MassHEAL%20-%20减少%20过量%20死亡%20by%2040%%20(2019-2023)

• 批准号: 10891912
• 负责人: JEFFREY H. SAMET
• 金额: $ 79.98万
• 依托单位: BOSTON MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-15 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10891912
• 关键词: Achievement; Acute; Address; Adoption; Age; Attention; Awareness; Black Populations; COVID-19 pandemic; Collaborations; Communities; Comparison arm; Continuity of Patient Care; Data; Data Analyses; Data Sources; Death Rate; Decision Making; Disparity; Equity; Ethnic Origin; Evidence based practice; Frequencies; Gender; Goals; Grant; Health; Health Services Accessibility; Homelessness; Individual; Infrastructure; Infusion procedures; Intervention; Kentucky; Learning; Legal system; Manuscripts; Massachusetts; Measures; Methods; Minority Groups; Naloxone; National Institute of Drug Abuse; Nature; New York; Not Hispanic or Latino; Ohio; Outcome; Outcome Study; Overdose reduction; Parents; Persons; Pharmaceutical Preparations; Policies; Population; Prevention education; Prevention strategy; Process; Protocols documentation; Publications; Race; Randomized; Reach, Effectiveness, Adoption, Implementation, and Maintenance; Reporting; Research Personnel; Resources; Site; Special Population; Surveys; Time; Training; Underserved Population; United States Substance Abuse and Mental Health Services Administration; Waiting Lists; Work; arm; black men; comparison intervention; contextual factors; demographics; design; disparity reduction; ethnic disparity; ethnic minority; ethnic minority population; healing; health equity; implementation strategy; insight; medication for opioid use disorder; meetings; member; minority communities; novel; opioid mortality; opioid overdose; opioid use disorder; overdose death; overdose education; overdose prevention; racial disparity; racial minority; racial minority population; response; satisfaction; sex; shared decision making; social health determinants; social stigma; sociodemographics; treatment as usual; trend

Project Summary/Abstract This supplement aims to explore the impact of the infusion of health equity principles on overdose prevention strategies during implementation of the Communities That Heal (CTH) intervention as part of the HEALing Communities Study (HCS). The HCS is a multi-site, parallel arm, cluster randomized, wait-list controlled trial evaluating the impact of the CTH intervention compared with usual care in wait-list communities, on overdose deaths. The overall goal of the HCS is to reduce opioid overdose deaths by 40% in 67 HCS communities across four states. Communities form coalitions to make shared decisions about what overdose prevention strategies to implement and how best to implement them, particularly strategies that promote Overdose Prevention Education and Naloxone Distribution (OEND) and Medications for Opioid Use Disorder (MOUD). While it is known that minoritized communities (whether due to race, ethnicity, gender, or LGBTQIA+ status) have less and poorer access to treatment for Opioid Use Disorder (OUD) and associated disparities in outcomes, at its outset, HCS did not explicitly aim to reduce disparities or measure the effect of centering equity on overdose prevention. This approach changed in 2020 with acute awareness of the racial and ethnic disparities within the COVID epidemic and the racial awakening in response to the George Floyd killing. This supplement will leverage the existing infrastructure and study stuff of its parent study to analyze survey and other qualitative data already collected. The primary data sources will include surveys of coalition members, completed at four time points during the study period; the Opioid-Overdose Reduction Continuum of Care Approach Tracker (ORCCAT), completed monthly by study staff, that includes overdose prevention information by strategy, sector, venue, population served, coalition approval date, implementation plan developed, date started, number of partners/practices associated with strategy, and mode of delivery; and REACH data, completed by study staff monthly once each strategy is implemented that includes information on number of persons reached and demographics of those reached (e.g., race, ethnicity, sex, age). Data analysis will include both quantitative analysis looking at associations between survey answers regarding health equity topics and incorporation of equity into strategies, as well as qualitative analysis examining how coalitions discussed and prioritized equity topics. This study will be guided by the parent study’s PRISM/RE-AIM(S) conceptual framework with a novel health equity lens to examine how diversifying coalitions and infusing opioid overdose prevention strategies with health equity principles may help reach minoritized communities and how these contextual factors and processes may interact to promote or impede health equity. Results from this study may be used to inform policies, strategies, and practices for incorporating health equity principles when implementing overdose prevention strategies.

项目概要/摘要 本增刊旨在探讨健康公平原则的注入对预防用药过量的影响 作为 HEALing 的一部分，实施“治愈社区”(CTH) 干预期间的策略 社区研究 (HCS) 是一项多中心、平行组、整群随机、等待名单对照试验。 评估 CTH 干预与候补社区常规护理相比对药物过量的影响 HCS 的总体目标是将 67 个 HCS 社区的阿片类药物过量死亡人数减少 40%。 四个州的社区组成联盟，就预防过量用药做出共同决定。 实施策略以及如何最好地实施它们，特别是促进过量用药的策略 预防教育和纳洛酮分配 (OEND) 以及阿片类药物使用障碍药物 (MOUD)。 虽然众所周知，少数群体（无论是由于种族、民族、性别还是 LGBTQIA+ 身份） 获得阿片类药物使用障碍 (OUD) 治疗的机会更少且更差，以及相关的差异 从一开始，HCS 并没有明确旨在减少差异或衡量中心化的效果 随着对种族和民族的敏锐认识，这种方法在 2020 年发生了变化 新冠疫情中的差异以及针对乔治·弗洛伊德之死的种族觉醒。 补充品将利用其母研究的现有基础设施和研究材料来分析调查和 已收集的其他定性数据主要数据来源将包括对联盟成员的调查， 在研究期间的四个时间点完成阿片类药物过量减少连续护理； 方法跟踪器 (ORCCAT)，由研究人员每月完成，其中包括过量预防信息 按战略、部门、地点、服务人口、联盟批准日期、制定的实施计划、日期 已启动、与战略相关的合作伙伴/实践数量、交付方式以及 REACH 数据； 每项战略实施后，研究人员每月完成一次，其中包括有关数量的信息 所接触的人数和所接触的人口统计数据（例如种族、民族、性别、年龄）。 这两项分析都着眼于有关健康公平主题的调查答案之间的关联 将公平纳入战略，以及定性分析检查联盟如何讨论和 本研究将以母研究的 PRISM/RE-AIM(S) 概念为指导。 具有新颖的健康公平视角的框架，以研究如何使联盟多样化并注入阿片类药物过量 符合健康公平原则的预防策略可能有助于覆盖少数群体社区，以及这些策略如何 背景因素和过程可能相互作用，促进或阻碍健康公平。本研究的结果可能会发生。 用于为纳入健康公平原则的政策、战略和实践提供信息 实施过量预防策略。

项目成果

Impacts of the New York State COVID-19 disaster emergency orders on prescription dispensing for opioids and medication for opioid use disorder.

纽约州 COVID-19 灾难紧急命令对阿片类药物处方配发和阿片类药物使用障碍药物的影响。

• 发表时间: 2023-04
• 作者: Suri, Abhinav;Feaster, Daniel J;Balise, Raymond R;Quinn, James;Nunes, Edward V;Gilbert, Louisa;El;Rundle, Andrew G
• 通讯作者: Rundle, Andrew G

Feasibility of paying people who use drugs cash to distribute naloxone within their networks.

向吸毒者支付现金以在其网络内分发纳洛酮的可行性。

• 发表时间: 2024-02-16
• 影响因子: 4.4
• 作者: Lewis, Nikki M;Smeltzer, Rebecca P;Baker, Trevor J;Sahovey, Andrea C;Baez, Justine;Hensel, Erika;Poole, Brandon;Stewart, Cecelia;Cogan, Allyson G;Bullard, Mackenzie;Taylor, Jessica L
• 通讯作者: Taylor, Jessica L

Corrigendum to "Model and approach for assessing implementation context and fidelity in the HEALing Communities Study" [Drug Alcohol Depend. 217 (2020) 108330].

“评估治愈社区研究中实施背景和保真度的模型和方法”的勘误[药物酒精依赖。

• 发表时间: 2021-07-01
• 影响因子: 4.2
• 作者: Knudsen, Hannah K;Drainoni, Mari;Gilbert, Louisa;Huerta, Timothy R;Oser, Carrie B;Aldrich, Alison M;Campbell, Aimee N C;Crable, Erika L;Garner, Bryan R;Glasgow, LaShawn M;Goddard;Marks, Katherine R;McAlearney, Ann Scheck;Og
• 通讯作者: Og

The role of health plans in addressing the opioid crisis: A qualitative study.

健康计划在解决阿片类药物危机中的作用：一项定性研究。

• 发表时间: 2023-06
• 作者: Davis, Margot Trotter;Bohler, Robert;Hodgkin, Dominic;Hamilton, Greer;Horgan, Constance
• 通讯作者: Horgan, Constance

Applied risk mapping and spatial analysis of address-level decedent data to inform opioid overdose interventions: The Massachusetts HEALing Communities Study.

应用地址级死者数据的风险绘图和空间分析来为阿片类药物过量干预提供信息：马萨诸塞州治愈社区研究。

• 发表时间: 2023-10-01
• 影响因子: 4.2
• 作者: Pustz, Jennifer;Srinivasan, Sumeeta;Shrestha, Shikhar;Larochelle, Marc R;Walley, Alexander Y;Samet, Jeffrey H;Babakhanlou;Carpenter, Jane F;Stopka, Thomas J
• 通讯作者: Stopka, Thomas J