DATA MANAGEMENT FOR CANCER DIAGNOSIS PROGRAM ACTIVITIES

癌症诊断计划活动的数据管理

基本信息

批准号：
10849595
负责人：
DAVE ANNETTE
金额：
$ 84.25万
依托单位：
INFORMATION MANAGEMENT SERVICES, INC.
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-08-01 至 2024-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10849595
关键词：
2019-nCoV Address Adopted Biological Biological Assay Biological Markers Biometry Blood COVID-19 Cancer Control Cancer Patient Characteristics Clinical Clinical Data Clinical Management Clinical Trials Clinical Trials Network Collaborations Communication Computers Consult Consultations Contractor Custom Data Data Analyses Data Collection Data Commons Data Element Data Files Data Security Data Set Databases Detection Development Diagnosis Disease Division of Cancer Treatment and Diagnosis Documentation Effectiveness Electronic Mail Electronics Enrollment Ensure Event Excision Extramural Activities Failure Frequencies Generations Genomics Grant Group Meetings Human Resources Image Immune response Individual Institution Laboratories Laboratory Study Length Link Logic Logistics Manuals Master of Science Medidata Methods Mission Modification Molecular Analysis Monitor Names National Cancer Institute National Cancer Program Natural History Online Systems Outcome Patients Performance Positive Test Result Preparation Prevention Process Production Quality Control Radiation Oncology Recurrence Reporting Research Research Personnel Resources Secure Serology Services Shipping Specific qualifier value Specimen Statistical Data Interpretation Structure Support Contracts System Techniques Telephone Text Time United States Dept. of Health and Human Services United States National Institutes of Health United States Public Health Service Update Virus anticancer research application programming interface biobank cancer diagnosis cancer palliative treatment cancer rehabilitation clinical database clinical research site data acquisition data de-identification data exchange data management data repository design experience falls follow-up individual responsibility meetings member programs sample collection statistics success symposium timeline working group

项目摘要

The National Cancer Institute (NCI) is an institute within the National Institutes of Health (NIH), one of eight agencies that compose the Public Health Service (PHS), Department of Health and Human Services (DHHS). The mission of the NCI is to plan, conduct, and coordinate the National Cancer program and involves (a) research on the causes, detection, diagnosis, prevention, treatment, and palliative care of cancers and on rehabilitation of the cancer patient and (b) demonstration of the effectiveness of cancer control methods and techniques. II. Background The Division of Cancer Treatment and Diagnosis (DCTD) of the NCI has initiated a natural history study, NCI COVID-19 in Cancer Patients Study (NCCAPS): A Longitudinal Natural History Study to investigate the course of disease in cancer patients with positive test results for SARS-CoV-2, the virus that causes the disease COVID-19. Across the NCI’s clinical trials networks, patients who enroll will have clinical data, imaging data and longitudinal blood or other biospecimens collected over a two-year period for laboratory analysis. NCI will use its existing Medidata Rave system to acquire and manage the clinical data and the Imaging and Radiation Oncology Core (IROC) to manage the imaging data. Several different kinds of laboratory analyses are planned to investigate biological aspects of the disease, including but not limited to genomics, serology, and immune response, and to examine associations of biological features with clinical variables and outcomes. Laboratory studies will take place at multiple institutions, both at NCI-Frederick and at several non-government academic and commercial laboratories. The data analysis effort will be led by the Biometric Research Program (BRP) in DCTD, in collaboration with the participating laboratories and other members of the study team.