Hispanic Stroke Prevention Intervention Research Program

西班牙裔中风预防干预研究计划

• 批准号: 8732055
• 负责人: Ralph L. Sacco
• 金额: $ 7.48万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8732055
• 关键词: Address; Adherence; Aging; Biological; Blood Pressure; Caribbean region; Chronic Disease; Communities; Data; Disease Management; Effectiveness; Ethnic Origin; Family member; Florida; Future; Guidelines; Health; Healthcare Systems; Hispanics; Hospitals; Information Technology; Intervention Studies; Knowledge; Lead; Mexican Americans; Minority; Minority Groups; Minority-Serving Institution; Modeling; Patients; Pharmacists; Population; Preventive Intervention; Puerto Rico; Race; Registries; Research; Research Personnel; Risk; Risk Factors; Secondary to; Stroke; Stroke prevention; Subgroup; Training and Education; Universities; acute stroke; blood glucose regulation; data management; design; health care delivery; high risk; improved; innovation; intervention program; multidisciplinary; novel; programs; psychosocial; randomized trial; rapid growth; statistics

DESCRIPTION (provided by applicant): Hispanics are the largest minority group and by 2050 will be constitute 30% of the US population. Although Mexican Americans are the largest subgroup, Caribbean Hispanics are the second largest subgroup in the U.S. The aging and rapid growth of the Hispanic population will lead to increases in the impact of stroke. Innovative strategies are needed to reduce stroke risk and eliminate disparities among Hispanics. Our Hispanic Stroke Prevention Intervention Research Program is a collaborative application from the University of Miami and the University of Puerto Rico aimed at reducing stroke disparities in the Hispanic community. The central theme of our program is risk factor control among Hispanics at risk of stroke. In project I, we will assess in a randomized trial the effectiveness o an innovative secondary stroke prevention intervention program to improve the control of risk factors, uses a health care delivery model that has been successful for chronic disease management in minority communities, integrates pharmacists in the enhancement of adherence, and state of the art mobile information technology. In project II, we will systematically evaluate the determinants of blood pressure variability and glucose control among high-risk Hispanic family members of stroke patients. We will assess novel psychosocial, sociocultural, healthcare system, and biological variables as part of a conceptual model that incorporates psychosocial adversities, reserve capacity, and cumulative vulnerabilities as determinants of 24hour blood pressure variability. In project III we will create the Florida Puerto Rico Stroke Registry by collating data from 140 hospitals that are currently collecting Get With the Guidelines-Stroke data to help identify stroke disparities by race, ethnicity, and region and educate stakeholders in approaches to improve stroke quality regarding stroke disparities. Our program includes three cores: administrative core, the research/education training core, and the data management and statistics core. Our multidisciplinary program unites investigators across two minority-serving institutions, addresses significant gaps in our knowledge of stroke risk in Hispanics, and will provide results that can have an immediate impact on future primary and secondary stroke prevention efforts.

描述（由申请人提供）：西班牙裔是最大的少数群体，到2050年将占美国人口的30％。尽管墨西哥裔美国人是最大的亚组，但加勒比西班牙裔是美国的第二大亚组，但西班牙裔人口的衰老和快速增长将导致中风的影响增加。需要创新的策略来降低中风风险并消除西班牙裔的差异。我们的西班牙裔中风预防干预研究计划是迈阿密大学和波多黎各大学的合作应用程序，旨在减少西班牙裔社区的中风差异。我们计划的中心主题是在西班牙裔风险中控制风险的风险因素。在项目I中，我们将在一项随机试验中评估有效性o创新的二级预防干预计划以改善风险因素的控制，使用一种医疗保健提供模型，该模型已成功地为少数民族社区的慢性疾病管理而成功，将药剂师纳入依从性和艺术移动信息技术的依从性和状态。在项目II中，我们将系统地评估中风患者的高风险西班牙裔家庭成员的血压变异性和葡萄糖控制的决定因素。我们将评估新颖的社会心理，社会文化，医疗保健系统和生物学变量，作为概念模型的一部分，该模型融合了社会心理逆境，预备役能力和累积脆弱性作为24小时血压变异性的决定因素。在第三项目中，我们将创建波多黎各佛罗里达州 RICO中风注册中心通过将目前正在收集的140家医院的数据与指南中风数据进行整理，以帮助确定种族，种族和地区的中风差异，并在提高中风差异方面的中风质量的方法中教育利益相关者。我们的计划包括三个核心：行政核心，研究/教育培训核心以及数据管理和统计核心。我们的多学科计划将两个少数派服务机构的调查人员团结在一起，解决了我们对西班牙裔中风风险的了解的巨大差距，并将提供可能对未来的初级和次级预防工作产生直接影响的结果。