Hispanic Stroke Prevention Intervention Research Program

西班牙裔中风预防干预研究计划

• 批准号: 8732055
• 负责人: Ralph L. Sacco
• 金额: $ 7.48万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8732055
• 关键词: Address; Adherence; Aging; Biological; Blood Pressure; Caribbean region; Chronic Disease; Communities; Data; Disease Management; Effectiveness; Ethnic Origin; Family member; Florida; Future; Guidelines; Health; Healthcare Systems; Hispanics; Hospitals; Information Technology; Intervention Studies; Knowledge; Lead; Mexican Americans; Minority; Minority Groups; Minority-Serving Institution; Modeling; Patients; Pharmacists; Population; Preventive Intervention; Puerto Rico; Race; Registries; Research; Research Personnel; Risk; Risk Factors; Secondary to; Stroke; Stroke prevention; Subgroup; Training and Education; Universities; acute stroke; blood glucose regulation; data management; design; health care delivery; high risk; improved; innovation; intervention program; multidisciplinary; novel; programs; psychosocial; randomized trial; rapid growth; statistics

DESCRIPTION (provided by applicant): Hispanics are the largest minority group and by 2050 will be constitute 30% of the US population. Although Mexican Americans are the largest subgroup, Caribbean Hispanics are the second largest subgroup in the U.S. The aging and rapid growth of the Hispanic population will lead to increases in the impact of stroke. Innovative strategies are needed to reduce stroke risk and eliminate disparities among Hispanics. Our Hispanic Stroke Prevention Intervention Research Program is a collaborative application from the University of Miami and the University of Puerto Rico aimed at reducing stroke disparities in the Hispanic community. The central theme of our program is risk factor control among Hispanics at risk of stroke. In project I, we will assess in a randomized trial the effectiveness o an innovative secondary stroke prevention intervention program to improve the control of risk factors, uses a health care delivery model that has been successful for chronic disease management in minority communities, integrates pharmacists in the enhancement of adherence, and state of the art mobile information technology. In project II, we will systematically evaluate the determinants of blood pressure variability and glucose control among high-risk Hispanic family members of stroke patients. We will assess novel psychosocial, sociocultural, healthcare system, and biological variables as part of a conceptual model that incorporates psychosocial adversities, reserve capacity, and cumulative vulnerabilities as determinants of 24hour blood pressure variability. In project III we will create the Florida Puerto Rico Stroke Registry by collating data from 140 hospitals that are currently collecting Get With the Guidelines-Stroke data to help identify stroke disparities by race, ethnicity, and region and educate stakeholders in approaches to improve stroke quality regarding stroke disparities. Our program includes three cores: administrative core, the research/education training core, and the data management and statistics core. Our multidisciplinary program unites investigators across two minority-serving institutions, addresses significant gaps in our knowledge of stroke risk in Hispanics, and will provide results that can have an immediate impact on future primary and secondary stroke prevention efforts.

描述（由申请人提供）：西班牙裔是最大的少数族裔，到 2050 年将占美国人口的 30%。虽然墨西哥裔美国人是最大的亚群，但加勒比裔西班牙裔是美国第二大亚裔群体。西班牙裔人口的老龄化和快速增长将导致中风影响的增加。需要创新策略来降低中风风险并消除西班牙裔之间的差异。我们的西班牙裔中风预防干预研究计划是迈阿密大学和波多黎各大学的合作应用，旨在减少西班牙裔社区的中风差异。我们计划的中心主题是控制有中风风险的西班牙裔人的危险因素。在项目一中，我们将通过一项随机试验评估创新的二级中风预防干预计划的有效性，以改善对危险因素的控制，使用在少数族裔社区慢性病管理方面取得成功的医疗保健提供模式，将药剂师纳入增强依从性和最先进的移动信息技术。在项目二中，我们将系统评估中风患者高危西班牙裔家庭成员血压变异性和血糖控制的决定因素。我们将评估新的心理社会、社会文化、医疗保健系统和生物变量，作为概念模型的一部分，该概念模型将心理社会逆境、储备能力和累积脆弱性作为 24 小时血压变异性的决定因素。在项目 III 中，我们将创建佛罗里达港 Rico 中风登记处通过整理来自 140 家医院的数据，这些医院目前正在收集中风指南数据，以帮助确定按种族、民族和地区划分的中风差异，并教育利益相关者如何提高中风差异方面的中风质量。我们的项目包括三个核心：行政核心、研究/教育培训核心、数据管理和统计核心。我们的多学科计划将两个少数族裔服务机构的研究人员联合起来，解决我们对西班牙裔中风风险知识的重大差距，并将提供对未来一级和二级中风预防工作产生直接影响的结果。