Eunice Kennedy Shriver NICHD Maternal Fetal Medicine Units Network (U10)

尤尼斯·肯尼迪·施赖弗 (Eunice Kennedy Shriver) NICHD 母胎医学单位网络 (U10)

• 批准号: 8442911
• 负责人: BRIAN M CASEY
• 金额: $ 29.73万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-05-05 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8442911
• 关键词: Birth; Caring; Clinical Protocols; Collaborations; Commit; Databases; Diagnosis; Discipline of obstetrics; Faculty; Hospitals; Hypothyroidism; Manuscripts; Medical center; Mission; National Institute of Child Health and Human Development; Patients; Perinatal; Physicians; Population; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Premature Birth; Preparation; Productivity; Protocols documentation; Research; Specific qualifier value; Texas; Thyroxine; Time; Universities; Woman; computerized; control trial; experience; fetal medicine; high risk; interest; patient population; randomized trial

DESCRIPTION (provided by applicant): This application describes the qualifications and experience of the maternal-fetal medicine faculty and research team at the University of Texas Southwestern (UT Southwestern) Medical Center and Parkland Hospital and the facilities and patient population available to carry out clinical protocols sponsored by the NICHD Maternal-Fetal Medicine Units (MFMU) Network. UT Southwestern's Division of Maternal-Fetal Medicine includes 16 full-time faculty physicians certified in maternal-fetal medicine. In 2009, there were 14,275 obstetrical patients delivered at Parkland Hospital and approximately 49% were high-risk. Pregnancy complications of particular interest to the MFMU Network, for example, preterm birth and preeclampsia, are well represented in the obstetrics population at Parkland Hospital. A computerized perinatal database for births at Parkland Hospital, operational since 1982, continues to be a centerpiece in our center's academic productivity as well as an important component of our center's successful participation in the MFMU Network. Indeed, for the past 15 years, UT Southwestern's MFMU Network center has frequently been the first or second leading recruiter for Network protocols. In this last 5 year cycle, our center led the implementation of the randomized trial of thyroxine therapy for subclinical hypothyroidism or hypothyroxinemia diagnosed during pregnancy (TSH) study which successfully screened more than 97,000 women in 3 years. Our center alone screened 18,296 of these women. We have been active in all aspects of the MFMU Network, including concept proposal, subcommittee participation, and manuscript preparation importantly, the maternal-fetal medicine physicians at UT Southwestern are philosophically dedicated to rigorous controlled trials intended to objectively evaluate principles of obstetrical care consistent with the mission of the MFMU Network. The perinatal research team described has been actively involved with and committed to the MFMU Network for the past 15 years and seeks to continue this collaboration.

描述（由申请人提供）：本申请描述了德克萨斯大学西南大学（UT Southwestern）医疗中心和Parkland Hospital的孕产妇医学教师和研究团队的资格和经验，以及可通过NICHD MAITNAL-FET-FET-FET-FET-FET-FET MEDICATION（MFMU）发起的临床方案的设施和患者人群。 UT Southwestern的孕产妇医学部包括16位获得母亲医学认证的全日制教职员工。 2009年，帕克兰医院（Parkland Hospital）分娩了14,275例产科患者，高风险大约有49％。 MFMU网络特别感兴趣的怀孕并发症，例如早产和子痫前期，在Parkland医院的妇产基群体中很好地代表了。自1982年以来开始运作的Parkland Hospital的计算机围产期数据库继续是我们中心学术生产力的核心，也是我们中心成功参与MFMU网络的重要组成部分。确实，在过去的15年中，UT西南的MFMU网络中心经常成为网络协议的第一或第二领先招聘人员。在过去的5年周期中，我们的中心领导了甲状腺素治疗在怀孕期间诊断出的亚临床甲状腺功能减退症或亚甲状腺素血症（TSH）研究的随机试验，该试验在三年内成功筛查了97,000多名女性。仅我们的中心就筛选了其中18,296名这些妇女。我们一直活跃于MFMU网络的各个方面，包括概念建议，小组委员会的参与和手稿准备，重要的是，UT西南部的母亲及其医学医生是哲学上专门针对严格的对照试验，该试验旨在客观地评估与MFMU网络一致的产科护理的原则。过去15年来，围产期研究团队一直积极参与并致力于MFMU网络，并寻求继续进行这项合作。