Facilitating Health Behavior Change among Morbidly Obese Adolescents

促进病态肥胖青少年健康行为的改变

• 批准号: 8204774
• 负责人: Robyn Jennifer Sysko
• 金额: $ 18.61万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-01 至 2014-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8204774
• 关键词: Address; Adherence; Adolescence; Adolescent; Adult; Affect; Aftercare; Age; Applications Grants; Appointment; Behavior Therapy; Behavioral; Body Weight; Body Weight decreased; Body mass index; Child; Chronic; Chronically Ill; Clinical; Cognitive; Data; Development; Disease; Eating; Effectiveness; Enrollment; Evaluation; Health; Health behavior change; Hypertension; Intervention; K-Series Research Career Programs; Life; Measurement; Measures; Medical; Mental Health; Mentored Patient-Oriented Research Career Development Award; Mentors; Methods; Moods; Morbid Obesity; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Operative Surgical Procedures; Outcome; Outcomes Research; Ovarian; Overweight; Parents; Patients; Pattern; Phenotype; Population; Prevalence; Psychological Factors; Psychopathology; Public Health; Recommendation; Reporting; Research; Research Personnel; Research Training; Risk; Schedule; Sleep; Symptoms; Syndrome; Telemedicine; Testing; Time; Training; Treatment outcome; United States; Visit; Weight; Youth; bariatric surgery; clinically significant; compliance behavior; depressive symptoms; eating pathology; experience; follow-up; mortality; novel; obesity in children; patient oriented; physical conditioning; programs; prospective; psychologic; public health relevance; success

DESCRIPTION (provided by applicant): With increasing rates of overweight and obesity among children and adolescents in the United States, there is an urgent need for effective weight loss treatments for younger patients. Recently, bariatric surgery has been considered as a treatment for seriously overweight adolescents because of the potential for substantial decreases in weight and subsequent improvements in physical health. The broad aim of this Mentored Patient- Oriented Career Development Award (K23) is to examine the interaction of psychological factors and serious overweight to determine if particular patterns of observable psychological symptoms (psychological phenotypes) are helpful in predicting outcomes of bariatric surgery. This project represents a crucial first step in a program of research to understand and address the interaction between mental and physical health among severely obese adolescents seeking bariatric surgery. This K23 application describes a plan of training and research for the candidate to become an independent clinical researcher with expertise in measuring relationships between mental and physical health over time and developing and validating novel treatments for eating and weight disorders in adolescence. The research plan involves: (1) the longitudinal prospective measurement of psychopathology among severely obese adolescents enrolled in a bariatric surgery program, and (2) the development and pilot testing of a treatment intervention delivered via telemedicine. Secondary aims of this application include evaluating the effect of psychiatric symptoms and the treatment intervention on compliance with post-surgery follow-up appointments and weight loss. The proposed research will require the candidate to obtain additional training in the treatment of obese adolescents, the provision of remote treatment (telemedicine), and longitudinal and treatment outcome research. Data from the proposed study will be broadly applicable to the study of interactions between psychological factors and compliance with treatment for youth with chronic health conditions. The results of the proposed K23 award will also be used in the development of a R-level grant application to conduct a larger trial evaluating the efficacy of the telemedicine treatment intervention. PUBLIC HEALTH RELEVANCE: The prevalence of overweight among children and adolescents is a national public health crisis. As more adolescents and their parents consider bariatric surgery for the treatment of severe obesity, additional research is needed to examine factors influencing compliance with surgical recommendations and the interaction of physical and mental health among seriously overweight adolescents.

描述（由申请人提供）：随着美国儿童和青少年超重和肥胖率的增加，迫切需要针对年轻患者的有效减肥治疗。最近，减肥手术被认为是严重超重青少年的一种治疗方法，因为它有可能大幅减轻体重并随后改善身体健康。该指导性患者导向职业发展奖（K23）的主要目标是检查心理因素与严重超重之间的相互作用，以确定可观察到的心理症状（心理表型）的特定模式是否有助于预测减肥手术的结果。该项目是了解和解决寻求减肥手术的严重肥胖青少年心理和身体健康之间相互作用的研究计划的关键第一步。该 K23 申请描述了一项培训和研究计划，旨在使候选人成为一名独立的临床研究人员，具有衡量心理和身体健康之间随时间变化的关系以及开发和验证青春期饮食和体重障碍的新疗法的专业知识。该研究计划包括：（1）对参加减肥手术计划的严重肥胖青少年的精神病理学进行纵向前瞻性测量，以及（2）通过远程医疗提供的治疗干预措施的开发和试点测试。该应用程序的次要目的包括评估精神症状的影响以及治疗干预对术后随访预约和体重减轻的依从性。拟议的研究将要求候选人获得肥胖青少年治疗、提供远程治疗（远程医疗）以及纵向和治疗结果研究方面的额外培训。拟议研究的数据将广泛适用于研究心理因素与患有慢性疾病的青少年的治疗依从性之间的相互作用。拟议的 K23 奖项的结果还将用于开发 R 级拨款申请，以进行更大规模的试验，评估远程医疗治疗干预的功效。 公共卫生相关性：儿童和青少年超重的流行是一场全国性的公共卫生危机。随着越来越多的青少年及其父母考虑通过减肥手术来治疗严重肥胖，需要进行更多研究来检查影响手术建议依从性的因素以及严重超重青少年身心健康的相互作用。