South Carolina Clinical & Translational Research Institute (SCTR)

南卡罗来纳州临床

基本信息

批准号：
10820346
负责人：
KATHLEEN T. BRADY
金额：
$ 72.49万
依托单位：
MEDICAL UNIVERSITY OF SOUTH CAROLINA
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-08-09 至 2025-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10820346
关键词：
Acceleration Address Administrative Supplement Affect Area Award Back Biomedical Research Biotechnology Businesses Caring Clinical Research Collaborations Country County Development Discipline Disclosure Dissemination and Implementation Diverse Workforce Economics Education Educational Curriculum Environment Fostering Foundations Funding Geographic Locations Grant Growth Health Health Priorities Health system Healthcare Healthcare Systems Heterogeneity Home Human Individual Informatics Intellectual Property Interdisciplinary Study Intervention Investments Learning Licensing Link Marketing Medical Medically Underserved Area Methodology Methods Mission Occupations Parents Pennsylvania Population Heterogeneity Positioning Attribute Process Productivity Public Health Recording of previous events Research Research Institute Research Personnel Research Training Resources Rural Science Secure Small Business Innovation Research Grant Small Business Technology Transfer Research Source South Carolina Structure Support System System Technology Therapeutic Training Training and Infrastructure Translating Translational Research Translations Universities Vision Work commercialization digital health experience flexibility health disparity improved innovation innovative technologies invention knowledge base medically underserved meetings method development new technology outreach parent grant patient population practice setting product development programs research and development rural underserved sabbatical social health determinants success technological innovation telehealth tool translational barrier translational therapeutics underserved community

项目摘要

PROJECT SUMMARY – SCTR INSTITUTE Parent Award UL1-TR001450 Since 2009, the South Carolina Clinical and Translational Research Institute (SCTR) has transformed the research environment across South Carolina (SC) by creating a Learning Health System that supports high- quality clinical and translational research (CTR) and fosters collaboration and innovation. Headquartered at the Medical University of South Carolina (MUSC), SCTR has engaged stakeholders and created statewide partnerships to improve care and address social determinants of health across SC. However, greater than 75% of SC is rural, and all 46 counties contain areas designated as medically underserved, so health disparities remain an issue. Over the next five years, SCTR will strengthen its outreach to these medically underserved areas through collaboration with the Clemson University Health Extension Program and the MUSC Telehealth Center of Excellence. With a focus on implementation and dissemination as well as discovery, we will develop and demonstrate innovative technologies and outreach to improve the health of our stakeholders. We will build on prior successes and introduce innovative approaches to expand CTR across SC through the following aims: Aim 1. Extend and enhance high-quality, innovative, flexible curricula and training experiences for all levels of the CTR workforce, with particular emphasis on enhancing workforce heterogeneity and team science. Aim 2. Engage a diverse group of stakeholders as active partners in CTR to address health care priorities while enhancing the scientific knowledge base about collaboration and engagement. Aim 3. Promote greater inclusion acrossthe full translational spectrumof research by engaging investigators from many disciplines and patient populations from diverse demographic backgrounds and geographic areas. Aim 4. Develop, demonstrate and disseminate innovative methods and processes to address barriers and accelerate the translation of research discoveries to improvements in human health that can be generalized to a variety of practice settings. Aim 5. Enhance the conduct of translational research through the development of secure and innovative informatics and digital health solutions, tools and methodologies that affect every aspect of CTR. SCTR’s vision is to be a major force in facilitating the translation of innovative science into practice to address the health priorities of the citizens of SC and beyond. To achieve this vision, SCTR’s mission is to catalyze the development of methods and technologies that lead to more efficient translation of biomedical discoveries into interventions that improve individual and public health. SCTR will serve as the statewide academic home for CTR, one that is well-integrated with SC’s healthcare systems and provides essential support for innovative, efficient, multidisciplinary research and research training. We will work within SCTR, with our partners across SC and with the CTSA Consortium to realize this vision.

项目摘要 – SCTR 研究所家长奖 UL1-TR001450 自 2009 年以来，南卡罗来纳州临床和转化研究所 (SCTR) 改变了通过创建支持高水平的学习健康系统，在整个南卡罗来纳州 (SC) 建立研究环境高质量的临床和转化研究（CTR）并促进合作和创新。南卡罗来纳医科大学 (MUSC)、SCTR 与利益相关者合作并创建了联邦改善护理并解决整个南卡罗来纳州健康问题社会决定因素的伙伴关系。 SC 75% 是农村地区，所有 46 个县都包含被指定为医疗服务不足的地区，因此卫生未来五年，差异仍然是一个问题，SCTR 将加强对这些医疗领域的推广。通过与克莱姆森大学健康推广计划和 MUSC 远程医疗卓越中心专注于实施和传播以及发现，我们将开发和展示创新技术和推广活动，以改善人们的健康我们将在之前的成功基础上引入创新方法来提高点击率。整个 SC 通过以下目标：目标 1. 扩展和加强各级高质量、创新、灵活的课程和培训经验的 CTR 员工队伍，特别强调增强员工队伍的异质性和团队科学。目标 2. 让不同的利益相关者群体成为 CTR 的积极合作伙伴，以解决医疗保健优先事项同时增强有关协作和参与的科学知识库。目标 3. 通过吸引研究者参与，促进整个转化研究领域的更大包容性来自许多学科和来自不同人口背景和地理的患者群体地区。目标 4. 开发、展示和传播创新方法和流程，以解决障碍和加速将研究发现转化为可推广的人类健康改善到各种练习环境。目标 5. 通过开发安全和创新的技术来加强转化研究的开展影响点击率各个方面的信息学和数字健康解决方案、工具和方法。 SCTR 的愿景是成为促进创新科学转化为实践的主要力量解决 SC 及其他地区公民的健康优先事项为了实现这一愿景，SCTR 的使命是：促进方法和技术的发展，从而更有效地转化生物医学 SCTR 将作为囚犯发现改善个人和公共健康的干预措施。 CTR 的学术中心，与 SC 的医疗保健系统完美集成，并提供必要的我们将在 SCTR 内开展工作，支持创新、高效、多学科的研究和研究培训。与我们整个 SC 的合作伙伴以及 CTSA 联盟一起实现这一愿景。

项目成果

期刊论文数量（617）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Implementation of free-draft text messaging to enhance care retention and satisfaction for persons living with HIV infection

实施自由草稿短信，以提高艾滋病毒感染者的护理保留率和满意度

DOI：
10.1080/09540121.2023.2208320
发表时间：
2023-05-03
期刊：
AIDS Care
影响因子：
1.7
作者：
V. Fonner;T. Agostini;Rohan Desai;Peyton Hartzell;Lisa Martin;Eric G. Meissner
通讯作者：
Eric G. Meissner

Trends in Preterm Body Composition and Neurodevelopmental Outcomes after Discharge.

出院后早产儿身体成分和神经发育结果的趋势。

DOI：
发表时间：
2023
期刊：
影响因子：
2.5
作者：
Lach, Laura E;Chetta, Katherine E;Gregoski, Mathew J;Katikaneni, Lakshmi D
通讯作者：
Katikaneni, Lakshmi D

miR-145a Regulation of Pericyte Dysfunction in a Murine Model of Sepsis.

miR-145a 对败血症小鼠模型中周细胞功能障碍的调节。

DOI：
发表时间：
2020
期刊：
影响因子：
0
作者：
Wu, Yan;Li, Pengfei;Goodwin, Andrew J;Cook, James A;Halushka, Perry V;Zingarelli, Basilia;Fan, Hongkuan
通讯作者：
Fan, Hongkuan

The effect of oxytocin, gender, and ovarian hormones on stress reactivity in individuals with cocaine use disorder.

催产素、性别和卵巢激素对可卡因使用障碍个体应激反应的影响。