Human Tumor Atlas Network: Data Coordinating Center Extension

人类肿瘤图谱网络：数据协调中心扩展

基本信息

批准号：
10818705
负责人：
Ethan Cerami
金额：
$ 200.72万
依托单位：
DANA-FARBER CANCER INST
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-04-04 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10818705
关键词：
Acceleration Archives Atlases Cells Clinical Cloud Computing Collaborations Communities Coupled Dana-Farber Cancer Institute Data Data Analyses Data Commons Data Coordinating Center Data Scientist Development Documentation Education and Outreach Educational Materials Ensure Evolution Fostering Funding Genomics Human Image Immunogenomics Individual Institution Intuition Location Malignant Neoplasms Memorial Sloan-Kettering Cancer Center Molecular Patients Performance Prevention strategy Procedures Research Research Personnel Research Support Resistance development Resources Services Slide Synapses Systems Biology Technology Translational Research Visualization Work anticancer research application programming interface cBioPortal cancer genomics cancer therapy centralized portal cloud based cloud platform community building community involvement data acquisition data dissemination data hub data management data portal data resource data standards data submission data visualization digital human genome sequencing improved large scale data novel open source operation outreach program pathology imaging radiological imaging shared database software development success tool treatment strategy tumor tumor progression tumorigenesis web portal working group

项目摘要

Project Summary/Abstract We propose to continue managing the operations of the data coordinating center (DCC) for the Human Tumor Atlas Network (HTAN) with responsibilities for managing, curating, and disseminating the data and resources generated through this network. We have provided, and will continue to provide, key services to organize and support the Research Centers that comprise the network, and foster a community based on collaboration, transparency, and sharing. Our primary scientific objective is to accelerate the discovery of mechanisms governing tumorigenesis, progression, and evolution, which will lead to improved prevention and treatment strategies for patients. We aim to achieve this by providing technology services coupled with best practices to expedite data acquisition and dissemination to HTAN researchers, as well as the broader scientific community. HTAN data is now available via the HTAN Data Portal, the Synapse platform, Minerva, CellXGene, cBioPortal, Google BigQuery, the NCI Cancer Research Data Service (CDS) and the NCI Image Data Commons (IDC). We will continue to release HTAN data to the wider scientific community and further develop visualization, annotation, and analysis tools in order to meet the needs of HTAN and the diverse cancer research community – including data scientists and statisticians to biologists and clinicians – as new types of data are generated.

项目概要/摘要我们建议继续管理数据协调中心（DCC）的运营人类肿瘤图谱网络 (HTAN) 负责管理、策划和传播我们提供的数据和资源，以及将继续提供关键服务来组织和支持研究中心组成网络，并培育一个基于协作、透明和我们的主要科学目标是加速发现治理机制。肿瘤的发生、进展和进化，这将导致预防和治疗的改进我们的目标是通过提供技术服务和帮助患者实现这一目标。加速数据采集和向 HTAN 研究人员传播的最佳实践，以及更广泛的科学界现在可以通过 HTAN 数据门户获取 HTAN 数据。 Synapse 平台、Minerva、CellXGene、cBioPortal、Google BigQuery、NCI 癌症研究数据服务（CDS）和NCI图像数据共享（IDC）我们将继续发布。将 HTAN 数据提供给更广泛的科学界，并进一步开发可视化、注释和分析工具以满足 HTAN 和多样化癌症研究界的需求 – 包括数据科学家和统计学家、生物学家和信徒——因为新型数据正在出现生成的。