Interpersonal Stress, Social Media, and Risk for Adolescent Suicidal Thoughts and Behaviors

人际压力、社交媒体以及青少年自杀想法和行为的风险

基本信息

批准号：
10815112
负责人：
RANDY PATRICK AUERBACH
金额：
$ 95.72万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-14 至 2028-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10815112
关键词：
17 year old Address Adolescent Age Amygdaloid structure Anterior Biological Biological Markers Biological Process Buffers Cause of Death Characteristics Chronic Clinical Clinical assessments Coupling Data Development Emergency department visit Enrollment Evaluation Event Exhibits Exposure to Feedback Feeling suicidal Functional Magnetic Resonance Imaging Future Generations Goals Hair Hate Hospitalization Hydrocortisone Insula of Reil Interruption Interview Lead Life Link Measures Mediating Mental disorders Methods Natural Language Processing Pathway interactions Patient Self-Report Persons Physiological Physiological Processes Predisposition Process Public Health Recording of previous events Reporting Research Risk Risk Behaviors Risk Factors Sampling Severities Social Environment Social Network Social Processes Social support Speech Stress Suicide Suicide attempt Testing Time Victimization Violence Youth adolescent suicide digital experience follow up assessment high risk hypothalamic-pituitary-adrenal axis ideation innovation neural neural correlate neural network novel peer preventive intervention recruit response social social capital social media suicidal suicidal adolescent suicidal behavior suicidal risk suicide rate temporal measurement theories

项目摘要

Project Summary Over the past 15 years, suicide rates among adolescents have increased ~60%. Recently, problematic social media use has been linked to the emergence of suicidal thoughts and behaviors (STB), perhaps reflecting greater interpersonal stress exposure. Understanding the type, timing, and severity of interpersonal stress exposure is critical to understand STB risk, which requires carefully characterizing exposures present in their digital lives through a deep interrogation of real-time interactions within social media. In line with the Stress Generation Framework, adolescents experiencing psychiatric disorders possess characteristics that increase the occurrence of interpersonal stress, which may include negative social media exposures. Accordingly, this project will identify social neural susceptibilities that may increase the occurrence of negative social media exposures and examine physiological processes that are impacted by negative social media exposures over time. Our study will include adolescents ages 14-17 (N=300), which will be oversampled for youth at high risk for suicide (n=200), defined as STB in the past 3 months and/or a past-year suicide attempt. Additionally, we will recruit adolescents with psychiatric disorders but without a lifetime history of STB (n=100), providing an opportunity to identify biological markers and temporally refined social media exposures that characterize risk for STB as opposed to identifying risk factors that associate with psychiatric disorders more broadly. Comprehensive clinical assessments will be completed at baseline, and additionally, we will probe past-year user-generated content to assess dynamic changes in negative exposures to characterize core interpersonal processes across social media platforms, including: (a) online victimization (e.g., harassment, hate speech), (b) reduced social capital (e.g., reduced social network size), and (c) reduced social support (e.g., reduced engagement, reciprocity of messaging). We also will collect baseline fMRI neural responses characterizing social processes and assess chronic HPA axis activity. At the 2-, 4-, and 6-month follow-up assessments, interviews, social media data, HPA axis activity, and self-reports will be re-assessed. The overarching goals is to examine the relationship between biological processes and social media exposures, particularly with regards to elucidating suicide risk. First, we will test whether social neural network alterations increase susceptibility to negative social media exposures. Second, we will test whether negative social media exposures negatively impact HPA axis activity. Last, we will test whether negative social media exposures, social neural alterations, HPA axis activity, and their interactions lead to the emergence of suicide events (i.e., actual, interrupted, or aborted attempts; active suicidal ideation with method, intent, or plan; emergency department visits or psychiatric hospitalizations for STB). Through this comprehensive approach, we will address a critical public health initiative by identifying those who are susceptible to negative social media exposures, and providing actionable markers to reduce the needless loss of life among young people.

项目概要过去 15 年中，青少年自杀率增加了约 60%。最近有问题社交媒体的使用与自杀念头和行为（STB）的出现有关，这或许反映了更大的人际压力暴露。了解人际压力的类型、时间和严重程度暴露对于了解 STB 风险至关重要，这需要仔细描述其存在的暴露特征通过对社交媒体内实时交互的深入探究来实现数字生活。与压力相符一代框架，经历精神疾病的青少年具有增加的特征人际压力的发生，其中可能包括负面的社交媒体曝光。据此，这该项目将识别可能增加负面社交媒体发生率的社交神经敏感性暴露并检查受负面社交媒体暴露影响的生理过程时间。我们的研究将包括 14-17 岁的青少年 (N=300)，将对高危青少年进行过抽样自杀 (n=200)，定义为过去 3 个月内有 STB 和/或过去一年有自杀企图。此外，我们将招募患有精神疾病但无 STB 终生病史的青少年 (n=100)，提供有机会识别表征风险的生物标记和临时改进的社交媒体曝光针对 STB，而不是确定与更广泛的精神疾病相关的危险因素。全面的临床评估将在基线时完成，此外，我们将调查过去一年的情况用户生成的内容，用于评估负面暴露的动态变化，以表征核心人际关系跨社交媒体平台的流程，包括：(a) 在线受害（例如骚扰、仇恨言论），(b) 社会资本减少（例如，社交网络规模缩小），以及 (c) 社会支持减少（例如，社会支持减少）参与、消息互惠）。我们还将收集表征社交特征的基线功能磁共振成像神经反应处理和评估慢性 HPA 轴活动。在 2、4 和 6 个月的后续评估、访谈中，社交媒体数据、HPA 轴活动和自我报告将被重新评估。总体目标是检查生物过程和社交媒体曝光之间的关系，特别是在阐明自杀风险。首先，我们将测试社交神经网络的改变是否会增加对负面的社交媒体曝光。其次，我们将测试负面的社交媒体曝光是否会产生负面影响影响 HPA 轴活性。最后，我们将测试负面的社交媒体曝光、社交神经改变、 HPA 轴活动及其相互作用导致自杀事件的出现（即实际的、中断的或失败的尝试；有方法、意图或计划的主动自杀意念；急诊科就诊或精神科因 STB 住院）。通过这种综合方法，我们将解决一项重要的公共卫生举措通过识别那些容易受到社交媒体负面曝光影响的人，并提供可操作的标记减少年轻人不必要的生命损失。