Training in Lung Science

肺科学培训

基本信息

批准号：
10704525
负责人：
R. Adams Dudley
金额：
$ 32.4万
依托单位：
UNIVERSITY OF MINNESOTA
依托单位国家：
美国
项目类别：
财政年份：
1994
资助国家：
美国
起止时间：
1994-07-15 至 2024-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10704525
关键词：
Lung Science Training

项目摘要

ABSTRACT: This proposal is the fifth competing renewal of the University of Minnesota Training Grant in Lung Science requesting funding of 4 pre-doctoral and 6 postdoctoral training positions (currently 4 and 8). Since year 10, this Training Grant has provided more than 70 trainees with the opportunity to develop strong foundations in lung science. In this period 47 post-doctoral (21 MD, 23 PhD, 3 MD-PhD) and 19 pre-doctoral (15 PhD graduate students and 3 MD–PhD students) trainees completed T32 support. The major aim of our Training Program is to provide rigorous scientific, leadership, and team science training to launch careers in lung- related research. Multidisciplinary advisory teams guide career development using Individualized Development Plans enabling: physician-scientists to become independent investigators examining scientific questions related to human lung disease; PhD scientists to gain knowledge of lung biology, promoting long term careers in basic and translational lung research; and graduate students from the MD-PhD program and other established degree-granting programs to nurture their interest and develop their skills in lung research. MD trainees are strongly encouraged to do formal coursework and/or obtain advanced degrees to optimize their opportunities for successful investigative careers. Training is focused in 3 major curricular areas: (1) Cell & Molecular Biology; (2) Clinical Research & Public Health; and (3) Systems Biology, Bioengineering; & Bio-Informatics. The curriculum provides formal training and degree opportunities for PhD degrees in a broad range of disciplines, Masters degrees in Public Health or Clinical Research, and Certificate Programs in Clinical Research. The Training Faculty is drawn from 5 Academic Health Center colleges and the College of Science & Engineering, providing broad expertise, clustered in thematic domains related to lung diseases. New faculty added with this renewal deepen the expertise in bioinformatics, health services research, bio-engineering, clinical trials and chronic disease outcomes. PhD trainees receive systematic exposure to the fundamentals of lung disease and have the opportunity to join faculty in relevant clinical settings. Comprehensive resources and stable research funding in each area continue to provide an outstanding training environment.

抽象的：该提案是明尼苏达大学肺科学培训补助金的第五次竞争更新请求资助 4 个博士前培训职位和 6 个博士后培训职位（目前为 4 个和 8 个）。这项培训补助金为 70 多名学员提供了在以下方面打下坚实基础的机会在此期间，有 47 名博士后（21 名医学博士、23 名博士、3 名医学博士-博士）和 19 名博士前人员（15 名博士）。研究生和 3 名医学博士-博士生) 受训人员完成了 T32 支持我们培训的主要目标。该计划旨在提供严格的科学、领导力和团队科学培训，以开启肺部职业生涯相关研究。多学科咨询团队利用个性化发展指导职业发展。计划使：医师科学家成为研究科学问题的独立研究者与人类肺部疾病相关的博士科学家获得肺部生物学知识，促进长期职业生涯基础和转化肺研究；以及医学博士项目和其他项目的研究生建立了学位授予计划，以培养他们对肺部研究的兴趣并发展他们的技能。强烈鼓励学员完成正式课程和/或获得高级学位以优化他们的能力成功调查生涯的机会。培训主要集中在 3 个主要课程领域：(1) 细胞与分子生物学；(2) 临床研究与公共；健康；（3）系统生物学、生物工程和生物信息学。以及获得广泛学科博士学位、公共卫生硕士学位或学位的机会临床研究和临床研究证书课程的培训教师来自 5 名。学术健康中心学院和科学与工程学院提供广泛的专业知识，集中在与肺部疾病相关的主题领域，此次更新增加了新的教师，加深了这一领域的研究。生物信息学、卫生服务研究、生物工程、临床试验和慢性病方面的专业知识博士生能够系统地了解肺部疾病的基础知识，并获得以下成果：有机会加入相关临床环境的教师队伍全面的资源和稳定的研究经费。每个领域都继续提供出色的培训环境。

项目成果

期刊论文数量（104）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Respiratory viruses and chronic rejection in lung transplant recipients.

呼吸道病毒和肺移植受者的慢性排斥反应。

DOI：
发表时间：
2002-05
期刊：
影响因子：
0
作者：
Billings, Joanne L;Hertz, Marshall I;Savik, Kay;Wendt, Christine H
通讯作者：
Wendt, Christine H

Hepatocyte growth factor stimulates migration of type II alveolar epithelial cells on the provisional matrix proteins fibronectin and fibrinogen.

肝细胞生长因子刺激 II 型肺泡上皮细胞在临时基质蛋白纤连蛋白和纤维蛋白原上迁移。

DOI：
发表时间：
1999-07
期刊：
影响因子：
9.6
作者：
Kim, H J;Sammak, P J;Ingbar, D H
通讯作者：
Ingbar, D H

Targeted overexpression of Bcl-XL in B-lymphoid cells results in lymphoproliferative disease and plasma cell malignancies.

B 淋巴细胞中 Bcl-XL 的靶向过度表达会导致淋巴组织增生性疾病和浆细胞恶性肿瘤。

DOI：
发表时间：
2004-04-01
期刊：
影响因子：
20.3
作者：
Linden, Michael;Kirchhof, Nicole;Carlson, Cathy;Van Ness, Brian
通讯作者：
Van Ness, Brian

Evidence and Role for Bacterial Mucin Degradation in Cystic Fibrosis Airway Disease.

细菌粘蛋白降解在囊性纤维化气道疾病中的证据和作用。

DOI：
发表时间：
2016
期刊：
影响因子：
6.7
作者：
Flynn, Jeffrey M;Niccum, David;Dunitz, Jordan M;Hunter, Ryan C
通讯作者：
Hunter, Ryan C

Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs.

翻译后修饰的黄体酮受体指导乳腺癌干细胞相关基因程序的配体特异性表达。

DOI：
发表时间：
2017-04-17
期刊：
影响因子：
0
作者：
Knutson, Todd P;Truong, Thu H;Ma, Shihong;Brady, Nicholas J;Sullivan, Megan E;Raj, Ganesh;Schwertfeger, Kathryn L;Lange, Carol A
通讯作者：
Lange, Carol A