Capacity Building for Neurodevelopmental Research on Maya Children’s Language Environment

玛雅儿童语言环境神经发育研究的能力建设

• 批准号: 10688270
• 负责人: Laura M. Justice
• 金额: $ 16.43万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-23 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10688270
• 关键词: 3 year old; Address; Adult; Area; Brain; Brain region; Buffers; Caregiver well-being; Caregivers; Child; Child Development; Child Language; Chronic; Competence; Comprehensive Health Care; Country; Data; Data Analyses; Database Management Systems; Development; Disease; Educational workshop; Enrollment; Environment; Exposure to; Family; Fostering; Foundations; Funding; Growth; Health; Home; Home environment; Household; Income; Indigenous; Intervention; Language; Language Development; Language Disorders; Lead; Longevity; Longitudinal Studies; Maintenance; Malnutrition; Measures; Methods; Mexico; Modeling; Monitor; Nature; Neurodevelopmental Disorder; Parent-Child Relations; Patient Recruitments; Personal Satisfaction; Pilot Projects; Population; Poverty; Prevalence; Questionnaires; Reporting; Research; Research Activity; Research Design; Research Ethics; Research Project Grants; Risk; Role; Rural; Structure; Testing; Time; Training; Work; behavior measurement; caregiving; design; educational atmosphere; experience; human subject protection; improved; indexing; interest; literacy; member; nervous system disorder; neurodevelopment; prevent; programs; screening; skills; tool

Project Summary This Exploratory/Developmental Research Grant will provide support for `global brain and nervous system disorders research across the lifespan' via two foci: (1) developing foundations for sustainable neuro- health research capacity in Mexico's Yucatán state focused on the early years of brain development for Yucatec Maya children, and (2) improving understanding of influences on Yucatec Maya children's early language trajectories. Specific Aim 1 is to improve local research capacity at the Mexico-based Solyluna A.C. to plan, conduct, and disseminate research on language-specific neurodevelopmental function and disorders among Yucatec Maya children. Specific Aim 2 is to conduct a pilot longitudinal study of the home environment and its influence on Yucatec Maya children's early language trajectories. For the latter, we use behavioral measures of Spanish and Mayan language skill, which serve to approximate the cortical structure and function of language-supporting brain regions. To address Aim 1, we engage in two-years of activities designed to develop the research capabilities of the Solyluna-based team in eight areas: (1) research ethics and human-subject protections, (2) participant recruitment, screening, enrollment, and maintenance; (3) implementation of child language assessments in Mayan and Spanish with integrity, (4) development, piloting, and implementation of caregiver questionnaires, (5) implementation of observational tools to measure the home environment, (6) data-entry, cleaning, and database management, (7) data analyses and interpretation, and (8) dissemination. These competencies will be explicitly addressed in six capacity-building workshops and aligned data-analysis working sessions. The OSU-based team and expert consultants have expertise in all eight areas and also bring substantive experience aligned to the longitudinal pilot study. To address Aim 2, we design, implement, and disseminate a longitudinal pilot study involving 100 3- year-old Yucatec Maya children and their caregivers. Dyads will participate in study activities over an 18-month period. Tentatively, we expect to collect a comprehensive caregiver questionnaire at baseline and child language assessments and home observations at 4 time-points with roughly 4- to 5-month intervals. Home observations include activities designed to measure caregiver well-being, household hardship, parent-child interaction quality, and exposure to child-directed talk. Multilevel growth-curve models will be used to investigate the language trajectories for children captured at four time-points and to examine the contribution of the home-environment indices to these trajectories.

项目概要 这项探索性/发展性研究补助金将为“全球大脑和神经系统”提供支持 整个生命周期的系统疾病研究通过两个重点：（1）为可持续的神经系统疾病奠定基础 墨西哥尤卡坦州的健康研究能力重点关注儿童早期大脑发育 尤卡坦玛雅儿童，以及（2）提高对尤卡坦玛雅儿童早期影响的理解 具体目标 1 是提高墨西哥 Solyluna A.C. 的本地研究能力。 计划、开展和传播有关语言特定神经发育功能和障碍的研究 具体目标 2 是对尤卡坦玛雅儿童进行家庭环境试点纵向研究。 及其对尤卡坦玛雅儿童早期语言轨迹的影响 对于后者，我们使用行为学。 测量西班牙语和玛雅语言技能，用于近似皮质结构和功能 支持语言的大脑区域。 为了实现目标 1，我们开展了为期两年的活动，旨在培养以下人员的研究能力： Solyluna 团队在八个领域：(1) 研究伦理和受试者保护，(2) 参与者 (3) 儿童语言评估的实施； 诚信的玛雅语和西班牙语，(4) 开发、试点和实施护理人员调查问卷， (5) 使用观察工具来测量家庭环境，(6) 数据输入、清理和 数据库管理，(7) 数据分析和解释，以及 (8) 传播。 六次能力建设研讨会和统一的数据分析工作会议明确讨论这一问题。 俄勒冈州立大学的团队和专家顾问拥有所有八个领域的专业知识，并带来了实质性的成果 与纵向试点研究相一致的经验。 为了实现目标 2，我们设计、实施和传播了一项纵向试点研究，涉及 100 3- 7 岁的尤卡坦玛雅儿童及其照顾者将参加为期 18 个月的学习活动。 暂时，我们希望收集一份关于基线和儿童的全面的照顾者调查问卷。 大约每隔 4 至 5 个月在 4 个时间点进行语言评估和家庭观察。 观察包括旨在衡量照顾者福祉、家庭困难、亲子关系的活动 互动质量和接触儿童导向的谈话将被用来 调查在四个时间点捕获的儿童的语言轨迹，并检查 这些轨迹的家庭环境指数。