The Reproductive Aging Conference

生殖老龄化会议

• 批准号: 10683677
• 负责人: Jennifer L Garrison
• 金额: $ 4.9万
• 依托单位: BUCK INSTITUTE FOR RESEARCH ON AGING
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-15 至 2026-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10683677
• 关键词: Acceleration; Address; Affect; Age; Aging; Area; Attitude; Award; Biological Models; Biology; Biology of Aging; California; Cardiovascular system; Cell Aging; Clinical; Clinical Sciences; Collaborations; Communication; Creativeness; Data; Dedications; Development; Discipline; Education; Elderly; Emerging Technologies; Ensure; Environmental Risk Factor; Faculty; Feedback; Female; Fertility; Fostering; Funding; Future; Genetic; Germ Cells; Goals; Gonadal structure; Health; Human; International; Libido; Longevity; Metabolic; Modeling; Molecular; Morbidity - disease rate; Nature; Oral; Outcome; Participant; Performance; Physiological Processes; Postdoctoral Fellow; Property; Regulation; Reproduction; Reproductive Biology; Reproductive Sciences; Reproductive system; Request for Applications; Research; Research Personnel; Resort; Resource Sharing; Resources; Rest; Role; Scholarship; Science; Scientist; Senior Scientist; Shapes; Somatic Cell; Students; System; Therapeutic; Tissues; Travel; cancer type; career; healthspan; healthy aging; improved; interest; lectures; male; meetings; men; minority trainee; mortality; multidisciplinary; new technology; next generation; posters; reproductive; reproductive organ; reproductive senescence; reproductive tract; senescence; sexual dimorphism; skeletal; skills; symposium; synergism; training opportunity; undergraduate student

PROJECT SUMMARY We are requesting funds to support the Reproductive Aging Conference annually for 3 years, 2023 - 2025. The 2023 meeting will be held at the Omni Rancho Las Palmas Resort (Palm Springs, California, USA) on May 2 - 5, 2023. This will be the second meeting following the Inaugural conference in June 2022. Aging in the gonad dramatically affects aging in somatic tissues, yet we know little about the mechanisms regulating healthy aging in reproductive organs, nor how this crosstalk is achieved. The Reproductive Aging conference will focus on understanding mechanisms that regulate aging in reproductive tissues and their relationship to overall organismal healthspan and longevity. Funds are requested each year to help cover expenses of 1) invited speakers and 2) meritorious junior scientists (students, postdoctoral fellows and junior faculty) and minority trainees who will benefit from formal and informal interactions with senior scientists, to present their research findings, receive feedback from experts in the field, and exchange ideas for shaping the field. To our knowledge, this is the only international meeting dedicated entirely to the topic of reproductive aging. The goal of the Reproductive Aging conference is to showcase research and stimulate collaborations that bridge the disciplines of reproductive biology and aging research to help define new paradigms to accelerate progress. Our primary objective is to become the premier forum for coalescing the field and fostering the discussion of concepts and presentation of research at the forefront of discovery related to aging in the reproductive system and its connection to aging in the rest of the body. Reproductive aging research encompasses multiple fronts of interest: identification of the molecular and cellular mechanisms that regulate aging in reproductive organs that facilitate overall healthspan and longevity; mechanisms of germ cell and niche aging and how these might regulate systemic aging; and developing new models to study these interactions. The intersection of these historically separate areas, the basic biology of aging and aging in the reproductive tract, have begun to merge around common molecular principles. Invited speakers include established as well as outstanding early career scientists selected for the quality of their science and ability to stimulate debate. This conference will provide a forum for both formal and informal interactions between trainees and faculty at all stages to promote the exchange of ideas and collaborative synergies around reproductive aging. Poster and oral presentations will examine reproductive aging at the molecular, cellular and organismal level, including its molecular drivers, and the effects of genetic and environmental factors on relevant cellular/system properties and interactions across diverse model systems ranging from worms to humans. This unique conference will bring together scientists tackling this problem from fundamental to clinical angles to brainstorm creative ways to build and strengthen the field.

项目概要 我们每年请求资金支持生殖老龄化会议，为期 3 年，即 2023 年至 2025 年。 2023 年会议将于 5 月在 Omni Rancho Las Palmas Resort（美国加利福尼亚州棕榈泉）举行 2023 年 2 日至 5 日。这将是继 2022 年 6 月首次会议之后的第二次会议。 性腺极大地影响体组织的衰老，但我们对其调节机制知之甚少 生殖器官的健康老化，以及这种串扰是如何实现的。生殖老龄化会议 将重点了解调节生殖组织衰老的机制及其与生殖组织的关系 整体有机健康寿命和寿命。每年都会请求资金来帮助支付以下费用：1) 特邀演讲嘉宾和 2) 有功绩的青年科学家（学生、博士后研究员和青年教师）以及 少数族裔受训者将受益于与资深科学家的正式和非正式互动，展示他们的成果 研究成果，接收该领域专家的反馈，并交流塑造该领域的想法。致我们的 据了解，这是唯一一次完全致力于生殖衰老主题的国际会议。 生殖老龄化会议的目标是展示研究并促进合作， 连接生殖生物学和衰老研究的学科，帮助定义新的范式以加速 进步。我们的主要目标是成为联合该领域并促进发展的首要论坛 讨论与衰老相关的前沿研究的概念和介绍 生殖系统及其与身体其他部位衰老的关系。生殖衰老研究 涵盖多个感兴趣的领域：识别调节的分子和细胞机制 生殖器官的衰老有利于整体健康和长寿；生殖细胞的机制和 生态位衰老以及它们如何调节系统性衰老；并开发新模型来研究这些 互动。这些历史上独立的领域的交集，衰老的基本生物学和衰老的领域 生殖道，已经开始围绕共同的分子原理进行融合。受邀演讲者包括 因其科学质量和能力而被选拔的知名科学家和杰出的早期职业科学家 激发辩论。本次会议将为双方之间的正式和非正式互动提供一个论坛 各个阶段的学员和教师促进思想交流和协作协同 生殖衰老。海报和口头演讲将从分子、细胞角度研究生殖衰老 和有机体水平，包括其分子驱动因素，以及遗传和环境因素对 相关的细胞/系统特性和跨不同模型系统的相互作用，从蠕虫到 人类。这次独特的会议将汇集从基础到临床解决这一问题的科学家 集思广益，集思广益，建立和加强该领域的创造性方法。